What to do when it is not so clear what to do: New opportunities for studies

Neil D. Ryan, Jae Won Kim, Bennett L. Leventhal

Research output: Contribution to journalArticle

Abstract

Patience is never easy when we have patients who need treatment and the currently available therapies are not optimal. As a result, progress in clinical studies designed to improve treatment of child and adolescent psychiatric disorders often seems unnecessarily, and painfully, slow to both clinicians and clinical researchers. We are often left wondering whether these time lags are necessary or are the result of unnecessary bureaucracy or antiquated research methods. Many among us may eschew waiting for data and simply move forward with the "off-label" use of both pharmacological/psychotherapeutic and environment/psychosocial interventions. Are there alternatives to consider? There certainly are. While the future of treatment studies in child psychiatry will look very much like the past, many future studies will take advantage of newer statistical approaches and our more informed hypotheses about the underlying neural systems changes associated with psychiatric symptoms. And, once again, hopefully, we will see that even small additions or changes in our methods and data analyses will allow us to fill our therapeutic cup further and faster.

Original languageEnglish
Pages (from-to)463-465
Number of pages3
JournalJournal of Child and Adolescent Psychopharmacology
Volume22
Issue number6
DOIs
StatePublished - 1 Dec 2012

Fingerprint

Child Psychiatry
Adolescent Psychiatry
Off-Label Use
Therapeutics
Psychiatry
Research Personnel
Pharmacology
Research
Clinical Studies

Cite this

@article{8dbb2ddb61434cc0b2fb271af3f09055,
title = "What to do when it is not so clear what to do: New opportunities for studies",
abstract = "Patience is never easy when we have patients who need treatment and the currently available therapies are not optimal. As a result, progress in clinical studies designed to improve treatment of child and adolescent psychiatric disorders often seems unnecessarily, and painfully, slow to both clinicians and clinical researchers. We are often left wondering whether these time lags are necessary or are the result of unnecessary bureaucracy or antiquated research methods. Many among us may eschew waiting for data and simply move forward with the {"}off-label{"} use of both pharmacological/psychotherapeutic and environment/psychosocial interventions. Are there alternatives to consider? There certainly are. While the future of treatment studies in child psychiatry will look very much like the past, many future studies will take advantage of newer statistical approaches and our more informed hypotheses about the underlying neural systems changes associated with psychiatric symptoms. And, once again, hopefully, we will see that even small additions or changes in our methods and data analyses will allow us to fill our therapeutic cup further and faster.",
author = "Ryan, {Neil D.} and Kim, {Jae Won} and Leventhal, {Bennett L.}",
year = "2012",
month = "12",
day = "1",
doi = "10.1089/cap.2012.2262",
language = "English",
volume = "22",
pages = "463--465",
journal = "Journal of Child and Adolescent Psychopharmacology",
issn = "1044-5463",
publisher = "Mary Ann Liebert Inc.",
number = "6",

}

What to do when it is not so clear what to do : New opportunities for studies. / Ryan, Neil D.; Kim, Jae Won; Leventhal, Bennett L.

In: Journal of Child and Adolescent Psychopharmacology, Vol. 22, No. 6, 01.12.2012, p. 463-465.

Research output: Contribution to journalArticle

TY - JOUR

T1 - What to do when it is not so clear what to do

T2 - New opportunities for studies

AU - Ryan, Neil D.

AU - Kim, Jae Won

AU - Leventhal, Bennett L.

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Patience is never easy when we have patients who need treatment and the currently available therapies are not optimal. As a result, progress in clinical studies designed to improve treatment of child and adolescent psychiatric disorders often seems unnecessarily, and painfully, slow to both clinicians and clinical researchers. We are often left wondering whether these time lags are necessary or are the result of unnecessary bureaucracy or antiquated research methods. Many among us may eschew waiting for data and simply move forward with the "off-label" use of both pharmacological/psychotherapeutic and environment/psychosocial interventions. Are there alternatives to consider? There certainly are. While the future of treatment studies in child psychiatry will look very much like the past, many future studies will take advantage of newer statistical approaches and our more informed hypotheses about the underlying neural systems changes associated with psychiatric symptoms. And, once again, hopefully, we will see that even small additions or changes in our methods and data analyses will allow us to fill our therapeutic cup further and faster.

AB - Patience is never easy when we have patients who need treatment and the currently available therapies are not optimal. As a result, progress in clinical studies designed to improve treatment of child and adolescent psychiatric disorders often seems unnecessarily, and painfully, slow to both clinicians and clinical researchers. We are often left wondering whether these time lags are necessary or are the result of unnecessary bureaucracy or antiquated research methods. Many among us may eschew waiting for data and simply move forward with the "off-label" use of both pharmacological/psychotherapeutic and environment/psychosocial interventions. Are there alternatives to consider? There certainly are. While the future of treatment studies in child psychiatry will look very much like the past, many future studies will take advantage of newer statistical approaches and our more informed hypotheses about the underlying neural systems changes associated with psychiatric symptoms. And, once again, hopefully, we will see that even small additions or changes in our methods and data analyses will allow us to fill our therapeutic cup further and faster.

UR - http://www.scopus.com/inward/record.url?scp=84871222496&partnerID=8YFLogxK

U2 - 10.1089/cap.2012.2262

DO - 10.1089/cap.2012.2262

M3 - Article

C2 - 23234590

AN - SCOPUS:84871222496

VL - 22

SP - 463

EP - 465

JO - Journal of Child and Adolescent Psychopharmacology

JF - Journal of Child and Adolescent Psychopharmacology

SN - 1044-5463

IS - 6

ER -