Waist circumference is the key risk factor for diabetes in Korean women with history of gestational diabetes

Nam H. Cho, Hak Chul Jang, Hae K. Park, Yong W. Cho

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

This study investigated relationships between various obesity indices and an onset of type 2 diabetes mellitus (TY2DM) in Korean women with history of gestational diabetes mellitus (GDM). A total of 909 women with history of GDM were enrolled from the four major hospitals, and the first postpartum follow-up examination was made at 6 weeks, and annually thereafter. During postpartum follow-up period, mean 2.13 ± 1.75 years, we conducted 2 h 75 g OGTT and measured glucose, insulin, c-peptide, lipid profiles, lifestyle and dietary evaluation. For obesity parameters, we measured body weight, body mass index (BMI), waist and hip circumference, subcutaneous fat thickness, body fat percent and weight using bioelectrical impedance tests. Diabetes incidence for 6 years was 12.8% and all the obesity indices were significantly higher in subjects with diabetes or glucose intolerance than those with normal glucose tolerance (p < 0.001). When obesity indices were compared between <25th versus >75th percentile, the waist circumference presented with the strongest relationship (odds ratio = 5.8, 95% CI 2.8-11.8). This relationship persisted, OR = 3.86 (95% CI 1.8-8.2), even after adjusting for the potential confounders. This prospective study revealed that waist circumference is one of the key risk factors for the onset of diabetes in Korean women with history of GDM.

Original languageEnglish
Pages (from-to)177-183
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume71
Issue number2
DOIs
StatePublished - 1 Feb 2006

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Gestational Diabetes
Waist Circumference
Obesity
Postpartum Period
Body Weight
Glucose
Glucose Intolerance
Subcutaneous Fat
Glucose Tolerance Test
Electric Impedance
Type 2 Diabetes Mellitus
Adipose Tissue
Life Style
Hip
Body Mass Index
Odds Ratio
Prospective Studies
Insulin
Lipids
Peptides

Keywords

  • Abdominal obesity
  • Diabetes
  • Epidemiology
  • GDM
  • Risk factors

Cite this

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abstract = "This study investigated relationships between various obesity indices and an onset of type 2 diabetes mellitus (TY2DM) in Korean women with history of gestational diabetes mellitus (GDM). A total of 909 women with history of GDM were enrolled from the four major hospitals, and the first postpartum follow-up examination was made at 6 weeks, and annually thereafter. During postpartum follow-up period, mean 2.13 ± 1.75 years, we conducted 2 h 75 g OGTT and measured glucose, insulin, c-peptide, lipid profiles, lifestyle and dietary evaluation. For obesity parameters, we measured body weight, body mass index (BMI), waist and hip circumference, subcutaneous fat thickness, body fat percent and weight using bioelectrical impedance tests. Diabetes incidence for 6 years was 12.8{\%} and all the obesity indices were significantly higher in subjects with diabetes or glucose intolerance than those with normal glucose tolerance (p < 0.001). When obesity indices were compared between <25th versus >75th percentile, the waist circumference presented with the strongest relationship (odds ratio = 5.8, 95{\%} CI 2.8-11.8). This relationship persisted, OR = 3.86 (95{\%} CI 1.8-8.2), even after adjusting for the potential confounders. This prospective study revealed that waist circumference is one of the key risk factors for the onset of diabetes in Korean women with history of GDM.",
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Waist circumference is the key risk factor for diabetes in Korean women with history of gestational diabetes. / Cho, Nam H.; Jang, Hak Chul; Park, Hae K.; Cho, Yong W.

In: Diabetes Research and Clinical Practice, Vol. 71, No. 2, 01.02.2006, p. 177-183.

Research output: Contribution to journalArticle

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