Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones

Wan Seo Dong Wan Seo, Hwan Kim Myung Hwan Kim, Koo Lee Sung Koo Lee, Jae Myung Seung Jae Myung, Gyeonghoon Kang, Kwon Ha Hyun Kwon Ha, D. J. Suh, Il Min Young Il Min

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Abstract

Background: Intrahepatic duct strictures are usually caused by intrahepatic duct stones and cholangitis. However, focal strictures of the intrahepatic duct unrelated to intrahepatic stones often pose diagnostic problems. This study was undertaken to prospectively evaluate the usefulness of percutaneous transhepatic cholangioscopy in patients with focal intrahepatic duct stricture and no evidence of a stone. Methods: Seventeen patients with focal strictures of the intrahepatic duct without any evidence of a stone were included. Percutaneous transhepatic cholangioscopic examination including procurement of biopsy specimens was performed after percutaneous transhepatic biliary drainage. Results: A histopathologic diagnosis was obtained in all patients (9 adenocarcinomas, 1 squamous cell carcinoma, 2 hepatocellular carcinomas, 2 adenomas, and 3 benign strictures). Of the 9 patients with bile duct adenocarcinoma, 8 underwent surgery and a curative resection was possible in 7 patients (88%). Five patients (63%) had early-stage bile duct cancer in which cancer invasion was limited to the mucosa or fibromuscular layer and there was no evidence of lymph node metastasis. Conclusions: Percutaneous transhepatic cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to choledocholithiasis is useful for diagnosis including the detection of early bile duct cancer.

Original languageEnglish
Pages (from-to)204-209
Number of pages6
JournalGastrointestinal Endoscopy
Volume49
Issue number2
DOIs
StatePublished - 1 Jan 1999

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Pathologic Constriction
Bile Duct Neoplasms
Adenocarcinoma
Choledocholithiasis
Cholangitis
Bile Ducts
Adenoma
Drainage
Hepatocellular Carcinoma
Squamous Cell Carcinoma
Mucous Membrane
Lymph Nodes
Neoplasm Metastasis
Biopsy
Neoplasms

Cite this

Dong Wan Seo, W. S., Myung Hwan Kim, H. K., Sung Koo Lee, K. L., Seung Jae Myung, J. M., Kang, G., Hyun Kwon Ha, K. H., ... Young Il Min, I. M. (1999). Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones. Gastrointestinal Endoscopy, 49(2), 204-209. https://doi.org/10.1016/S0016-5107(99)70487-6
Dong Wan Seo, Wan Seo ; Myung Hwan Kim, Hwan Kim ; Sung Koo Lee, Koo Lee ; Seung Jae Myung, Jae Myung ; Kang, Gyeonghoon ; Hyun Kwon Ha, Kwon Ha ; Suh, D. J. ; Young Il Min, Il Min. / Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones. In: Gastrointestinal Endoscopy. 1999 ; Vol. 49, No. 2. pp. 204-209.
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abstract = "Background: Intrahepatic duct strictures are usually caused by intrahepatic duct stones and cholangitis. However, focal strictures of the intrahepatic duct unrelated to intrahepatic stones often pose diagnostic problems. This study was undertaken to prospectively evaluate the usefulness of percutaneous transhepatic cholangioscopy in patients with focal intrahepatic duct stricture and no evidence of a stone. Methods: Seventeen patients with focal strictures of the intrahepatic duct without any evidence of a stone were included. Percutaneous transhepatic cholangioscopic examination including procurement of biopsy specimens was performed after percutaneous transhepatic biliary drainage. Results: A histopathologic diagnosis was obtained in all patients (9 adenocarcinomas, 1 squamous cell carcinoma, 2 hepatocellular carcinomas, 2 adenomas, and 3 benign strictures). Of the 9 patients with bile duct adenocarcinoma, 8 underwent surgery and a curative resection was possible in 7 patients (88{\%}). Five patients (63{\%}) had early-stage bile duct cancer in which cancer invasion was limited to the mucosa or fibromuscular layer and there was no evidence of lymph node metastasis. Conclusions: Percutaneous transhepatic cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to choledocholithiasis is useful for diagnosis including the detection of early bile duct cancer.",
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Dong Wan Seo, WS, Myung Hwan Kim, HK, Sung Koo Lee, KL, Seung Jae Myung, JM, Kang, G, Hyun Kwon Ha, KH, Suh, DJ & Young Il Min, IM 1999, 'Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones', Gastrointestinal Endoscopy, vol. 49, no. 2, pp. 204-209. https://doi.org/10.1016/S0016-5107(99)70487-6

Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones. / Dong Wan Seo, Wan Seo; Myung Hwan Kim, Hwan Kim; Sung Koo Lee, Koo Lee; Seung Jae Myung, Jae Myung; Kang, Gyeonghoon; Hyun Kwon Ha, Kwon Ha; Suh, D. J.; Young Il Min, Il Min.

In: Gastrointestinal Endoscopy, Vol. 49, No. 2, 01.01.1999, p. 204-209.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Usefulness of cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to intrahepatic stones

AU - Dong Wan Seo, Wan Seo

AU - Myung Hwan Kim, Hwan Kim

AU - Sung Koo Lee, Koo Lee

AU - Seung Jae Myung, Jae Myung

AU - Kang, Gyeonghoon

AU - Hyun Kwon Ha, Kwon Ha

AU - Suh, D. J.

AU - Young Il Min, Il Min

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Background: Intrahepatic duct strictures are usually caused by intrahepatic duct stones and cholangitis. However, focal strictures of the intrahepatic duct unrelated to intrahepatic stones often pose diagnostic problems. This study was undertaken to prospectively evaluate the usefulness of percutaneous transhepatic cholangioscopy in patients with focal intrahepatic duct stricture and no evidence of a stone. Methods: Seventeen patients with focal strictures of the intrahepatic duct without any evidence of a stone were included. Percutaneous transhepatic cholangioscopic examination including procurement of biopsy specimens was performed after percutaneous transhepatic biliary drainage. Results: A histopathologic diagnosis was obtained in all patients (9 adenocarcinomas, 1 squamous cell carcinoma, 2 hepatocellular carcinomas, 2 adenomas, and 3 benign strictures). Of the 9 patients with bile duct adenocarcinoma, 8 underwent surgery and a curative resection was possible in 7 patients (88%). Five patients (63%) had early-stage bile duct cancer in which cancer invasion was limited to the mucosa or fibromuscular layer and there was no evidence of lymph node metastasis. Conclusions: Percutaneous transhepatic cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to choledocholithiasis is useful for diagnosis including the detection of early bile duct cancer.

AB - Background: Intrahepatic duct strictures are usually caused by intrahepatic duct stones and cholangitis. However, focal strictures of the intrahepatic duct unrelated to intrahepatic stones often pose diagnostic problems. This study was undertaken to prospectively evaluate the usefulness of percutaneous transhepatic cholangioscopy in patients with focal intrahepatic duct stricture and no evidence of a stone. Methods: Seventeen patients with focal strictures of the intrahepatic duct without any evidence of a stone were included. Percutaneous transhepatic cholangioscopic examination including procurement of biopsy specimens was performed after percutaneous transhepatic biliary drainage. Results: A histopathologic diagnosis was obtained in all patients (9 adenocarcinomas, 1 squamous cell carcinoma, 2 hepatocellular carcinomas, 2 adenomas, and 3 benign strictures). Of the 9 patients with bile duct adenocarcinoma, 8 underwent surgery and a curative resection was possible in 7 patients (88%). Five patients (63%) had early-stage bile duct cancer in which cancer invasion was limited to the mucosa or fibromuscular layer and there was no evidence of lymph node metastasis. Conclusions: Percutaneous transhepatic cholangioscopy in patients with focal stricture of the intrahepatic duct unrelated to choledocholithiasis is useful for diagnosis including the detection of early bile duct cancer.

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U2 - 10.1016/S0016-5107(99)70487-6

DO - 10.1016/S0016-5107(99)70487-6

M3 - Article

VL - 49

SP - 204

EP - 209

JO - Gastrointestinal endoscopy

JF - Gastrointestinal endoscopy

SN - 0016-5107

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ER -