The immediate and sustained positive effects of meditation on resilience are mediated by changes in the resting brain

Seoyeon Kwak, Tae Young Lee, Wi Hoon Jung, Ji Won Hur, Dahye Bae, Wu Jeong Hwang, Kang Ik K. Cho, Kyung Ok Lim, So Yeon Kim, Hye Yoon Park, Jun Soo Kwon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

While recent studies have explored the maintenance of the effect of meditation on stress resilience, the underlying neural mechanisms have not yet been investigated. The present study conducted a highly controlled residential study of a 4-day meditation intervention to investigate the brain functional changes and long-term effects of meditation on mindfulness and resilience. Thirty participants in meditation practice and 17 participants in a relaxation retreat (control group) underwent magnetic resonance imaging scans at baseline and post-intervention and completed the Cognitive and Affective Mindfulness Scale (CAMS) and Resilience Quotient Test (RQT) at baseline, post-intervention, and the 3-month follow-up. All participants showed increased CAMS and RQT scores post-intervention, but only the meditation group sustained the enhancement after 3 months. Resting-state functional connectivity (rsFC) between the left rostral anterior cingulate cortex (rACC) and the dorsomedial prefrontal cortex (dmPFC), precuneus, and angular gyrus was significantly increased post-intervention in the meditation group compared with the relaxation group. The changes in rACC-dmPFC rsFC mediated the relationship between the changes in the CAMS and RQT scores and correlated with the changes in the RQT score both immediately and at 3 months post-intervention. Our findings suggest that increased rACC-dmPFC rsFC via meditation causes an immediate enhancement in resilience that is sustained. Since resilience is known to be associated with the preventative effect of various psychiatric disorders, the improvement in stress-related neural mechanisms may be beneficial to individuals at high clinical risk.

Original languageEnglish
JournalFrontiers in Human Neuroscience
Volume13
DOIs
StatePublished - 1 Feb 2019

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Meditation
Mindfulness
Brain
Gyrus Cinguli
Prefrontal Cortex
Parietal Lobe
Psychiatry
Maintenance
Magnetic Resonance Imaging
Control Groups

Keywords

  • Meditation
  • Mindfulness training
  • Resilience
  • Resting-state functional connectivity
  • Templestay

Cite this

Kwak, Seoyeon ; Lee, Tae Young ; Jung, Wi Hoon ; Hur, Ji Won ; Bae, Dahye ; Hwang, Wu Jeong ; Cho, Kang Ik K. ; Lim, Kyung Ok ; Kim, So Yeon ; Park, Hye Yoon ; Kwon, Jun Soo. / The immediate and sustained positive effects of meditation on resilience are mediated by changes in the resting brain. In: Frontiers in Human Neuroscience. 2019 ; Vol. 13.
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The immediate and sustained positive effects of meditation on resilience are mediated by changes in the resting brain. / Kwak, Seoyeon; Lee, Tae Young; Jung, Wi Hoon; Hur, Ji Won; Bae, Dahye; Hwang, Wu Jeong; Cho, Kang Ik K.; Lim, Kyung Ok; Kim, So Yeon; Park, Hye Yoon; Kwon, Jun Soo.

In: Frontiers in Human Neuroscience, Vol. 13, 01.02.2019.

Research output: Contribution to journalArticle

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