Abstract

Objective: To evaluate retrospectively the efficacy of the mandibular advancement device (MAD) in patients with obstructive sleep apnea in terms of positional dependency. Design: Retrospective analysis. Setting: Academic tertiary referral center. Patients: One hundred patients with obstructive sleep apnea treated with the MAD at the Department of Otorhinolaryngology sleep clinic were included from January 1, 2005, through December 31, 2010. Interventions: All patients underwent nocturnal fullnight polysomnography before and at least 3 months after intraoral MAD application. Main Outcome Measures: Treatment results and prognostic factors deciding the success of MAD application. Results: Of the 100 patients, 80 showed positional dependency and 20 showed nondependency. In the positiondependent obstructive sleep apnea group, the median (interquartile range) apnea-hypopnea index (AHI) decreased from 32.1 (24.4-41.9) to 8.6 (3.7-13.8) (P<.001); in the nondependent group, from 56.4 (26.2-71.5) to 15.7 (6.8-30.7) (P<.001). The success rate (AHI reduction ≥50% andAHI<10) was 57.5% and 30.0%in position-dependent and position-nondependent groups, respectively (P=.04). Conclusion: Identifying patients with obstructive sleep apnea as position dependent or nondependent may have important therapeutic implications in predicting the outcome of MAD treatment.

Original languageEnglish
Pages (from-to)479-483
Number of pages5
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume138
Issue number5
DOIs
StatePublished - 1 May 2012

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Mandibular Advancement
Obstructive Sleep Apnea
Equipment and Supplies
Apnea
Polysomnography
Otolaryngology
Tertiary Care Centers
Dependency (Psychology)
Sleep
Therapeutics
Outcome Assessment (Health Care)

Cite this

@article{405d8811faed48d8b5a19630752b9114,
title = "The effect of positional dependency on outcomes of treatment with a mandibular advancement device",
abstract = "Objective: To evaluate retrospectively the efficacy of the mandibular advancement device (MAD) in patients with obstructive sleep apnea in terms of positional dependency. Design: Retrospective analysis. Setting: Academic tertiary referral center. Patients: One hundred patients with obstructive sleep apnea treated with the MAD at the Department of Otorhinolaryngology sleep clinic were included from January 1, 2005, through December 31, 2010. Interventions: All patients underwent nocturnal fullnight polysomnography before and at least 3 months after intraoral MAD application. Main Outcome Measures: Treatment results and prognostic factors deciding the success of MAD application. Results: Of the 100 patients, 80 showed positional dependency and 20 showed nondependency. In the positiondependent obstructive sleep apnea group, the median (interquartile range) apnea-hypopnea index (AHI) decreased from 32.1 (24.4-41.9) to 8.6 (3.7-13.8) (P<.001); in the nondependent group, from 56.4 (26.2-71.5) to 15.7 (6.8-30.7) (P<.001). The success rate (AHI reduction ≥50{\%} andAHI<10) was 57.5{\%} and 30.0{\%}in position-dependent and position-nondependent groups, respectively (P=.04). Conclusion: Identifying patients with obstructive sleep apnea as position dependent or nondependent may have important therapeutic implications in predicting the outcome of MAD treatment.",
author = "Lee, {Chul Hee} and Jung, {Hahn Jin} and Lee, {Woo Hyun} and Rhee, {Chae Seo} and Yoon, {In Young} and Yun, {Pil Young} and Kim, {Jeong Whun}",
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The effect of positional dependency on outcomes of treatment with a mandibular advancement device. / Lee, Chul Hee; Jung, Hahn Jin; Lee, Woo Hyun; Rhee, Chae Seo; Yoon, In Young; Yun, Pil Young; Kim, Jeong Whun.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 138, No. 5, 01.05.2012, p. 479-483.

Research output: Contribution to journalArticle

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T1 - The effect of positional dependency on outcomes of treatment with a mandibular advancement device

AU - Lee, Chul Hee

AU - Jung, Hahn Jin

AU - Lee, Woo Hyun

AU - Rhee, Chae Seo

AU - Yoon, In Young

AU - Yun, Pil Young

AU - Kim, Jeong Whun

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Objective: To evaluate retrospectively the efficacy of the mandibular advancement device (MAD) in patients with obstructive sleep apnea in terms of positional dependency. Design: Retrospective analysis. Setting: Academic tertiary referral center. Patients: One hundred patients with obstructive sleep apnea treated with the MAD at the Department of Otorhinolaryngology sleep clinic were included from January 1, 2005, through December 31, 2010. Interventions: All patients underwent nocturnal fullnight polysomnography before and at least 3 months after intraoral MAD application. Main Outcome Measures: Treatment results and prognostic factors deciding the success of MAD application. Results: Of the 100 patients, 80 showed positional dependency and 20 showed nondependency. In the positiondependent obstructive sleep apnea group, the median (interquartile range) apnea-hypopnea index (AHI) decreased from 32.1 (24.4-41.9) to 8.6 (3.7-13.8) (P<.001); in the nondependent group, from 56.4 (26.2-71.5) to 15.7 (6.8-30.7) (P<.001). The success rate (AHI reduction ≥50% andAHI<10) was 57.5% and 30.0%in position-dependent and position-nondependent groups, respectively (P=.04). Conclusion: Identifying patients with obstructive sleep apnea as position dependent or nondependent may have important therapeutic implications in predicting the outcome of MAD treatment.

AB - Objective: To evaluate retrospectively the efficacy of the mandibular advancement device (MAD) in patients with obstructive sleep apnea in terms of positional dependency. Design: Retrospective analysis. Setting: Academic tertiary referral center. Patients: One hundred patients with obstructive sleep apnea treated with the MAD at the Department of Otorhinolaryngology sleep clinic were included from January 1, 2005, through December 31, 2010. Interventions: All patients underwent nocturnal fullnight polysomnography before and at least 3 months after intraoral MAD application. Main Outcome Measures: Treatment results and prognostic factors deciding the success of MAD application. Results: Of the 100 patients, 80 showed positional dependency and 20 showed nondependency. In the positiondependent obstructive sleep apnea group, the median (interquartile range) apnea-hypopnea index (AHI) decreased from 32.1 (24.4-41.9) to 8.6 (3.7-13.8) (P<.001); in the nondependent group, from 56.4 (26.2-71.5) to 15.7 (6.8-30.7) (P<.001). The success rate (AHI reduction ≥50% andAHI<10) was 57.5% and 30.0%in position-dependent and position-nondependent groups, respectively (P=.04). Conclusion: Identifying patients with obstructive sleep apnea as position dependent or nondependent may have important therapeutic implications in predicting the outcome of MAD treatment.

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