[18F]FDOPA PET/CT in Solid Pseudopapillary Tumor of the Pancreas: a Recurred Tumor Mimicking Splenosis

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Abstract

Solid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [18F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions such as splenosis. A 55-year-old woman underwent distal pancreatectomy and splenectomy for histologically confirmed SPT. She was also initially diagnosed with splenosis. During follow-up, sizes of multiple nodular lesions were increased, raising the possibility of peritoneal seeding of SPT. For diagnosis, a spleen scan and SPECT/CT were performed using 99mTc-labeled damaged red blood cells, which showed no uptake in the peritoneal nodules. Subsequent [18F]FDOPA PET/CT revealed [18F]FDOPA-avidity of the nodules. The patient underwent tumor resection surgery, and the nodules were pathologically confirmed as SPT.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalNuclear Medicine and Molecular Imaging
Volume58
Issue number2
DOIs
StatePublished - Apr 2024

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Korean Society of Nuclear Medicine 2023.

Keywords

  • PET/CT
  • Peritoneal seeding
  • Solid pseudopapillary tumor
  • Spleen scan
  • Splenosis
  • [F]FDOPA

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