Stellate ganglion block increases blood flow into the optic nerve head and the peripapillary retina in human

Hyeong Gon Yu, Hum Chung, Tae Gyoon Yoon, Kwang Won Yum, Hyun Jeong Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The effects of stellate ganglion block (SGB) on the blood flow of the optic nerve head (ONH) and the peripapillary retina, which plays an important role in the pathogenesis of a major blinding disease, e.g. glaucoma, are unclear. The aim of this study was to evaluate the effects of a sympathetic block on the blood flow of the ONH and the peripapillary retina. Heidelberg Retinal Flowmetry, which is a system incorporating a noninvasive confocal scanning laser Doppler flow meter, was used to measure the retinal blood flow. A unilateral stellate ganglion block was performed in 11 healthy subjects. The retinal blood flows were measured before, 30 and 120 min after SGB. On each occasion, three scans were obtained and the blood flow was analyzed. The systemic blood pressure (BP) and the intraocular pressure (IOP) were also measured at the set time points. The blood flow of the ONH and the peripapillary retina of the ipsilateral retina was significantly increased (P=0.001) by 106.8% and 98.7%, respectively, 30 min after SGB without accompanying significant changes in BP and IOP when compared to their baseline values; while those of the contralateral eyes did not change. The effect of SGB on blood flow in these areas disappeared 120 min after SGB. In conclusion, SGB may have a beneficial effect on ocular diseases associated with ischemia of the ONH and the peripapillary retina, e.g. glaucoma.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalAutonomic Neuroscience: Basic and Clinical
Volume109
Issue number1-2
DOIs
StatePublished - 28 Nov 2003

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Stellate Ganglion
Optic Disk
Retina
Intraocular Pressure
Glaucoma
Blood Pressure
Eye Diseases
Rheology
Healthy Volunteers
Lasers
Ischemia

Keywords

  • Autonomic nerve block
  • Human
  • Laser Doppler flowmetry
  • Retinal blood flow
  • Stellate ganglion

Cite this

Yu, Hyeong Gon ; Chung, Hum ; Yoon, Tae Gyoon ; Yum, Kwang Won ; Kim, Hyun Jeong. / Stellate ganglion block increases blood flow into the optic nerve head and the peripapillary retina in human. In: Autonomic Neuroscience: Basic and Clinical. 2003 ; Vol. 109, No. 1-2. pp. 53-57.
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Stellate ganglion block increases blood flow into the optic nerve head and the peripapillary retina in human. / Yu, Hyeong Gon; Chung, Hum; Yoon, Tae Gyoon; Yum, Kwang Won; Kim, Hyun Jeong.

In: Autonomic Neuroscience: Basic and Clinical, Vol. 109, No. 1-2, 28.11.2003, p. 53-57.

Research output: Contribution to journalArticle

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