Spectrum of opportunistic infections and malignancies in patients with human immunodeficiency virus infection in South Korea

Myoung don Oh, Sang Won Park, Hong Bin Kim, Ui Seok Kim, Nam Joong Kim, Hee Jung Choi, Dong Hyeon Shin, Joo Shil Lee, Kangwon Choe

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43 Scopus citations

Abstract

To determine the frequency and types of major opportunistic diseases in patients with HIV infection in South Korea, we reviewed the medical records of 173 HIV-infected patients. The patients were seen from 1985 to 1998 at a referral hospital for AIDS in South Korea. Most patients (85%) were male, and 107 (62%) were infected by heterosexual contacts. CD4+ lymphocyte counts at presentation were <200/μL in 27% of the patients. Tuberculosis was the most frequent opportunistic infection (25% of patients), followed by candidiasis (21%), herpes zoster (20%), Pneumocystis carinii pneumonia (10%), cytomegalovirus disease (9.8%). There were no cases of toxoplasmosis. Kaposi's sarcoma developed in 3 patients (1.7%), and non-Hodgkin's lymphoma, in 2 (1.2%). Eleven patients (6.4%) developed peripheral neuropathy, and 8 (4.6%) had HIV encephalopathy. Tuberculosis was the single most important HIV-related infection in South Korean patients.

Original languageEnglish
Pages (from-to)1524-1528
Number of pages5
JournalClinical Infectious Diseases
Volume29
Issue number6
DOIs
StatePublished - 1 Dec 1999

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