Sodium-calcium exchange tail current in atrial myocytes of the rabbit - An index of subsarcolemmal calcium concentrations?

Yung E. Earm, Won Kyung Ho, Insuk So, Chae Hun Leem

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In cardiac cells, sodium-calcium exchange is important in regulation of intracellular calcium concentration as a primary mechanism of calcium extrusion. Earm et al., [1, 2] recorded the inward current after short depolarizing pulses, and showed the inward current was a Na-Ca exchange current activated by intracellular calcium released from the sarcoplasmic reticulum (SR) and contributed to the generation of the late plateau phase of the action potential in rabbit atrial myocytes. Furthermore, by using fluorescence Ca indicator measurements, Lipp & Pott [3, 4] showed clearly that the inward current was activated by Ca release from the SR and is exclusively carried by a Na-Ca exchange mechanism.

Original languageEnglish
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 1992
EditorsJean Louis Coatrieux, Robert Plonsey, Jean Pierre Morucci, Swamy Laxminarayan
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages99-100
Number of pages2
ISBN (Electronic)0780307852
DOIs
StatePublished - 1992
Event14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 1992 - Paris, France
Duration: 29 Oct 19921 Nov 1992

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume1
ISSN (Print)1557-170X

Conference

Conference14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 1992
Country/TerritoryFrance
CityParis
Period29/10/921/11/92

Fingerprint

Dive into the research topics of 'Sodium-calcium exchange tail current in atrial myocytes of the rabbit - An index of subsarcolemmal calcium concentrations?'. Together they form a unique fingerprint.

Cite this