11 Citations (Scopus)

Abstract

Purpose. To investigate the value of additional transition zone (TZ) biopsies following 12-core biopsies in the detection and staging of prostate cancer. Methods. From October 2006 to March 2007, 199 transrectal sonographic (TRUS)-guided prostate biopsies (group 1) in 12 peripheral zones (PZ) were performed. Another 199 consecutive patients (group 2) underwent two TZ biopsies in addition to twelve PZ biopsies from March 2007 to July 2007. Mean prostate-specific antigen (PSA) level, prostate volume, Gleason score, and cancer detection rate of each group were compared. The anatomic distribution of prostate cancer in group 2 was also analyzed. Results. Prostate cancer was detected in 76 of 199 patients (38.2%) in group 1 and 71 out of 199 patients (35.3%) in group 2. The cancer detection rate, mean PSA level, prostate volume, and Gleason score were not statistically different in the 2 groups. Cancer was detected by additional TZ biopsies alone in just one out of 71 patients (1.4%). Conclusion. Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.

Original languageEnglish
Pages (from-to)281-284
Number of pages4
JournalJournal of Clinical Ultrasound
Volume37
Issue number5
DOIs
StatePublished - 1 Jun 2009

Fingerprint

Prostate
Biopsy
Prostatic Neoplasms
Neoplasm Grading
Prostate-Specific Antigen
Neoplasms

Keywords

  • Biopsy
  • Cancer
  • Prostate
  • Transition zone
  • Transrectal sonography

Cite this

@article{6a2c82d791b04048a883bbfc2671c985,
title = "Should transition zone biopsies be added to 12-core systematic biopsies of the prostate?",
abstract = "Purpose. To investigate the value of additional transition zone (TZ) biopsies following 12-core biopsies in the detection and staging of prostate cancer. Methods. From October 2006 to March 2007, 199 transrectal sonographic (TRUS)-guided prostate biopsies (group 1) in 12 peripheral zones (PZ) were performed. Another 199 consecutive patients (group 2) underwent two TZ biopsies in addition to twelve PZ biopsies from March 2007 to July 2007. Mean prostate-specific antigen (PSA) level, prostate volume, Gleason score, and cancer detection rate of each group were compared. The anatomic distribution of prostate cancer in group 2 was also analyzed. Results. Prostate cancer was detected in 76 of 199 patients (38.2{\%}) in group 1 and 71 out of 199 patients (35.3{\%}) in group 2. The cancer detection rate, mean PSA level, prostate volume, and Gleason score were not statistically different in the 2 groups. Cancer was detected by additional TZ biopsies alone in just one out of 71 patients (1.4{\%}). Conclusion. Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.",
keywords = "Biopsy, Cancer, Prostate, Transition zone, Transrectal sonography",
author = "Sung, {Il Hwang} and Lee, {Hak Jong} and Jeong, {Yeon Cho} and Seung, {Hyup Kim} and Sang, {Eun Lee} and Byun, {Seok Soo} and Sung, {Kyu Hong} and Ghee, {Young Choe}",
year = "2009",
month = "6",
day = "1",
doi = "10.1002/jcu.20565",
language = "English",
volume = "37",
pages = "281--284",
journal = "Journal of Clinical Ultrasound",
issn = "0091-2751",
publisher = "John Wiley and Sons Inc.",
number = "5",

}

TY - JOUR

T1 - Should transition zone biopsies be added to 12-core systematic biopsies of the prostate?

AU - Sung, Il Hwang

AU - Lee, Hak Jong

AU - Jeong, Yeon Cho

AU - Seung, Hyup Kim

AU - Sang, Eun Lee

AU - Byun, Seok Soo

AU - Sung, Kyu Hong

AU - Ghee, Young Choe

PY - 2009/6/1

Y1 - 2009/6/1

N2 - Purpose. To investigate the value of additional transition zone (TZ) biopsies following 12-core biopsies in the detection and staging of prostate cancer. Methods. From October 2006 to March 2007, 199 transrectal sonographic (TRUS)-guided prostate biopsies (group 1) in 12 peripheral zones (PZ) were performed. Another 199 consecutive patients (group 2) underwent two TZ biopsies in addition to twelve PZ biopsies from March 2007 to July 2007. Mean prostate-specific antigen (PSA) level, prostate volume, Gleason score, and cancer detection rate of each group were compared. The anatomic distribution of prostate cancer in group 2 was also analyzed. Results. Prostate cancer was detected in 76 of 199 patients (38.2%) in group 1 and 71 out of 199 patients (35.3%) in group 2. The cancer detection rate, mean PSA level, prostate volume, and Gleason score were not statistically different in the 2 groups. Cancer was detected by additional TZ biopsies alone in just one out of 71 patients (1.4%). Conclusion. Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.

AB - Purpose. To investigate the value of additional transition zone (TZ) biopsies following 12-core biopsies in the detection and staging of prostate cancer. Methods. From October 2006 to March 2007, 199 transrectal sonographic (TRUS)-guided prostate biopsies (group 1) in 12 peripheral zones (PZ) were performed. Another 199 consecutive patients (group 2) underwent two TZ biopsies in addition to twelve PZ biopsies from March 2007 to July 2007. Mean prostate-specific antigen (PSA) level, prostate volume, Gleason score, and cancer detection rate of each group were compared. The anatomic distribution of prostate cancer in group 2 was also analyzed. Results. Prostate cancer was detected in 76 of 199 patients (38.2%) in group 1 and 71 out of 199 patients (35.3%) in group 2. The cancer detection rate, mean PSA level, prostate volume, and Gleason score were not statistically different in the 2 groups. Cancer was detected by additional TZ biopsies alone in just one out of 71 patients (1.4%). Conclusion. Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.

KW - Biopsy

KW - Cancer

KW - Prostate

KW - Transition zone

KW - Transrectal sonography

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