Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease

Seon Young Ryu, Ahro Kim, Sang Yun Kim, Kyung Won Park, Kee Hyung Park, Young Chul Youn, Dong Woo Lee, Jun Young Lee, Jun Hong Lee, Jee Hyang Jeong, Seong Hye Choi, Hyun Jeong Han, Semi Kim, Seunghee Na, Misun Park, Hyeon Woo Yim, Dong Won Yang

Research output: Contribution to journalArticle

Abstract

Objectives: The present study examined self-reports and informant reports of cognitive function and discrepancies between the two reporting methods in healthy controls (HC), subjective cognitive decline (SCD), mild cognitive impairment (MCI), and very mild Alzheimer disease (AD) using three questionnaires. Methods: The study included a total of 300 individuals (mean age: 74.4 ± 5.7 y), including 130 HC, 70 SCD, 51 MCI, and 49 very mild AD patients. Self-ratings and informant ratings of cognitive function were assessed using the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C), AD8, and Subjective Memory Complaints Questionnaire (SMCQ). Awareness of cognitive functioning was measured on the basis of the discrepancy scores between self-reports and informant reports. Results: Group comparisons on questionnaire scores adjusting for age, education, and depressive symptoms showed that self-reports were lowest in HC than other groups, with no differences between SCD and MCI groups. Informant reports were lower in SCD than in MCI, while discrepancy scores were higher in SCD than in MCI (P <.001 for KDSQ-C and SMCQ; P =.076 for AD8). There were no differences in self-reports, informant reports, and discrepancy scores between MCI and AD groups. Conclusions: These results support the usefulness of informant-reported cognitive functioning to classify MCI among elderly with subjective cognitive complaints. In addition, discrepancies between self-reports and informant reports demonstrate that overestimation and underestimation of cognitive function may serve as a clinical indicator of SCD and MCI across the cognitive continuum, respectively.

Original languageEnglish
Pages (from-to)91-98
Number of pages8
JournalInternational Journal of Geriatric Psychiatry
Volume35
Issue number1
DOIs
StatePublished - 1 Jan 2020

Fingerprint

Alzheimer Disease
Self Report
Cognition
Cognitive Dysfunction
Dementia
Surveys and Questionnaires
Depression
Education
Control Groups

Keywords

  • Alzheimer disease
  • awareness
  • cognitive complaints
  • mild cognitive impairment
  • subjective cognitive decline

Cite this

Ryu, Seon Young ; Kim, Ahro ; Kim, Sang Yun ; Park, Kyung Won ; Park, Kee Hyung ; Youn, Young Chul ; Lee, Dong Woo ; Lee, Jun Young ; Lee, Jun Hong ; Jeong, Jee Hyang ; Choi, Seong Hye ; Han, Hyun Jeong ; Kim, Semi ; Na, Seunghee ; Park, Misun ; Yim, Hyeon Woo ; Yang, Dong Won. / Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease. In: International Journal of Geriatric Psychiatry. 2020 ; Vol. 35, No. 1. pp. 91-98.
@article{576cd6dcddcb481aaa6f1257f65bb38b,
title = "Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease",
abstract = "Objectives: The present study examined self-reports and informant reports of cognitive function and discrepancies between the two reporting methods in healthy controls (HC), subjective cognitive decline (SCD), mild cognitive impairment (MCI), and very mild Alzheimer disease (AD) using three questionnaires. Methods: The study included a total of 300 individuals (mean age: 74.4 ± 5.7 y), including 130 HC, 70 SCD, 51 MCI, and 49 very mild AD patients. Self-ratings and informant ratings of cognitive function were assessed using the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C), AD8, and Subjective Memory Complaints Questionnaire (SMCQ). Awareness of cognitive functioning was measured on the basis of the discrepancy scores between self-reports and informant reports. Results: Group comparisons on questionnaire scores adjusting for age, education, and depressive symptoms showed that self-reports were lowest in HC than other groups, with no differences between SCD and MCI groups. Informant reports were lower in SCD than in MCI, while discrepancy scores were higher in SCD than in MCI (P <.001 for KDSQ-C and SMCQ; P =.076 for AD8). There were no differences in self-reports, informant reports, and discrepancy scores between MCI and AD groups. Conclusions: These results support the usefulness of informant-reported cognitive functioning to classify MCI among elderly with subjective cognitive complaints. In addition, discrepancies between self-reports and informant reports demonstrate that overestimation and underestimation of cognitive function may serve as a clinical indicator of SCD and MCI across the cognitive continuum, respectively.",
keywords = "Alzheimer disease, awareness, cognitive complaints, mild cognitive impairment, subjective cognitive decline",
author = "Ryu, {Seon Young} and Ahro Kim and Kim, {Sang Yun} and Park, {Kyung Won} and Park, {Kee Hyung} and Youn, {Young Chul} and Lee, {Dong Woo} and Lee, {Jun Young} and Lee, {Jun Hong} and Jeong, {Jee Hyang} and Choi, {Seong Hye} and Han, {Hyun Jeong} and Semi Kim and Seunghee Na and Misun Park and Yim, {Hyeon Woo} and Yang, {Dong Won}",
year = "2020",
month = "1",
day = "1",
doi = "10.1002/gps.5224",
language = "English",
volume = "35",
pages = "91--98",
journal = "International Journal of Geriatric Psychiatry",
issn = "0885-6230",
publisher = "John Wiley and Sons Ltd",
number = "1",

}

Ryu, SY, Kim, A, Kim, SY, Park, KW, Park, KH, Youn, YC, Lee, DW, Lee, JY, Lee, JH, Jeong, JH, Choi, SH, Han, HJ, Kim, S, Na, S, Park, M, Yim, HW & Yang, DW 2020, 'Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease', International Journal of Geriatric Psychiatry, vol. 35, no. 1, pp. 91-98. https://doi.org/10.1002/gps.5224

Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease. / Ryu, Seon Young; Kim, Ahro; Kim, Sang Yun; Park, Kyung Won; Park, Kee Hyung; Youn, Young Chul; Lee, Dong Woo; Lee, Jun Young; Lee, Jun Hong; Jeong, Jee Hyang; Choi, Seong Hye; Han, Hyun Jeong; Kim, Semi; Na, Seunghee; Park, Misun; Yim, Hyeon Woo; Yang, Dong Won.

In: International Journal of Geriatric Psychiatry, Vol. 35, No. 1, 01.01.2020, p. 91-98.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Self- and informant-reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease

AU - Ryu, Seon Young

AU - Kim, Ahro

AU - Kim, Sang Yun

AU - Park, Kyung Won

AU - Park, Kee Hyung

AU - Youn, Young Chul

AU - Lee, Dong Woo

AU - Lee, Jun Young

AU - Lee, Jun Hong

AU - Jeong, Jee Hyang

AU - Choi, Seong Hye

AU - Han, Hyun Jeong

AU - Kim, Semi

AU - Na, Seunghee

AU - Park, Misun

AU - Yim, Hyeon Woo

AU - Yang, Dong Won

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Objectives: The present study examined self-reports and informant reports of cognitive function and discrepancies between the two reporting methods in healthy controls (HC), subjective cognitive decline (SCD), mild cognitive impairment (MCI), and very mild Alzheimer disease (AD) using three questionnaires. Methods: The study included a total of 300 individuals (mean age: 74.4 ± 5.7 y), including 130 HC, 70 SCD, 51 MCI, and 49 very mild AD patients. Self-ratings and informant ratings of cognitive function were assessed using the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C), AD8, and Subjective Memory Complaints Questionnaire (SMCQ). Awareness of cognitive functioning was measured on the basis of the discrepancy scores between self-reports and informant reports. Results: Group comparisons on questionnaire scores adjusting for age, education, and depressive symptoms showed that self-reports were lowest in HC than other groups, with no differences between SCD and MCI groups. Informant reports were lower in SCD than in MCI, while discrepancy scores were higher in SCD than in MCI (P <.001 for KDSQ-C and SMCQ; P =.076 for AD8). There were no differences in self-reports, informant reports, and discrepancy scores between MCI and AD groups. Conclusions: These results support the usefulness of informant-reported cognitive functioning to classify MCI among elderly with subjective cognitive complaints. In addition, discrepancies between self-reports and informant reports demonstrate that overestimation and underestimation of cognitive function may serve as a clinical indicator of SCD and MCI across the cognitive continuum, respectively.

AB - Objectives: The present study examined self-reports and informant reports of cognitive function and discrepancies between the two reporting methods in healthy controls (HC), subjective cognitive decline (SCD), mild cognitive impairment (MCI), and very mild Alzheimer disease (AD) using three questionnaires. Methods: The study included a total of 300 individuals (mean age: 74.4 ± 5.7 y), including 130 HC, 70 SCD, 51 MCI, and 49 very mild AD patients. Self-ratings and informant ratings of cognitive function were assessed using the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C), AD8, and Subjective Memory Complaints Questionnaire (SMCQ). Awareness of cognitive functioning was measured on the basis of the discrepancy scores between self-reports and informant reports. Results: Group comparisons on questionnaire scores adjusting for age, education, and depressive symptoms showed that self-reports were lowest in HC than other groups, with no differences between SCD and MCI groups. Informant reports were lower in SCD than in MCI, while discrepancy scores were higher in SCD than in MCI (P <.001 for KDSQ-C and SMCQ; P =.076 for AD8). There were no differences in self-reports, informant reports, and discrepancy scores between MCI and AD groups. Conclusions: These results support the usefulness of informant-reported cognitive functioning to classify MCI among elderly with subjective cognitive complaints. In addition, discrepancies between self-reports and informant reports demonstrate that overestimation and underestimation of cognitive function may serve as a clinical indicator of SCD and MCI across the cognitive continuum, respectively.

KW - Alzheimer disease

KW - awareness

KW - cognitive complaints

KW - mild cognitive impairment

KW - subjective cognitive decline

UR - http://www.scopus.com/inward/record.url?scp=85074721085&partnerID=8YFLogxK

U2 - 10.1002/gps.5224

DO - 10.1002/gps.5224

M3 - Article

C2 - 31650618

AN - SCOPUS:85074721085

VL - 35

SP - 91

EP - 98

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

SN - 0885-6230

IS - 1

ER -