Robot-assisted rehabilitation for total knee or hip replacement surgery patients: A systematic review and meta-analysis

Jun Il Yoo, Min Kyun Oh, Shi Uk Lee, Chang Han Lee

Research output: Contribution to journalArticlepeer-review


Background: This study was performed to update the current evidence and evaluate the effects of robot-assisted rehabilitation (RAR) in comparison with conventional rehabilitation (CR) in patients following total knee (TKR) or hip replacements (THR). Methods: PubMed Central, OVID Medline, Cochrane Collaboration Library, and EMBASE for a comprehensive search for all relevant studies, from database inception to July 2022. The following inclusion criteria were used to determine eligibility for studies: randomized and matched controlled trials recruiting men and women who underwent TKR and THR; and studies examining the effect of RAR on outcome measures of physical function and pain. Results: A total of 9 studies (230 patients) were included in this review and 4 were included in the meta-analysis. The meta-analysis of 2 studies showed that Hybrid Assistive Limb (HAL) training for 5 days, significantly improved pain measured on a visual analogue scale, compared to CR in patients following TKR (SMD = 1.05, 95% confidence interval [Cl] 0.39-1.71). Heterogeneity for I2value was lower than moderate (tau2= 0.0121; I2= 5%; P = .30). There were 2 studies that assessed self-selected walking speed. The meta-analysis of these studies showed that HAL training was significantly superior to CR in patients following TKR (SMD = 48.70, 95% Cl-50.53 to 147.94) at 2 months. A high heterogeneity was detected (P < .01; I2= 97%). Conclusion: The result of this systematic review and meta-analysis suggest that RAR may be an effective treatment in TKR and THR patients. However, high-quality studies are needed to verify the long-term effect on their recovery.

Original languageEnglish
Article number00088
JournalMedicine (United States)
Issue number40
StatePublished - 7 Oct 2022


  • meta-analysis
  • rehabilitation
  • robot
  • systematic review
  • total hip replacement
  • total knee replacement


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