Risk factor analysis for development of asymptomatic carotid stenosis in Koreans

Yun Jeong Lim, Young Wook Kim, Yeon Hyen Choe, Chang Seok Ki, Sue Kyung Park

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS ≥30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At sub-group analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalJournal of Korean Medical Science
Volume21
Issue number1
DOIs
StatePublished - Feb 2006

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Carotid Stenosis
Statistical Factor Analysis
Leukocyte Count
Hypertension
Hyperlipidemias
LDL Cholesterol
Smoking
Cerebrovascular Disorders
Internal Carotid Artery
Carotid Arteries
Aspirin
Myocardial Ischemia
Fasting
Ultrasonography
Atherosclerosis
Diabetes Mellitus
Multivariate Analysis
Retrospective Studies
Logistic Models
Cholesterol

Keywords

  • Atherosclerosis
  • Carotid stenosis
  • Risk factors

Cite this

Lim, Yun Jeong ; Kim, Young Wook ; Choe, Yeon Hyen ; Ki, Chang Seok ; Park, Sue Kyung. / Risk factor analysis for development of asymptomatic carotid stenosis in Koreans. In: Journal of Korean Medical Science. 2006 ; Vol. 21, No. 1. pp. 15-19.
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Risk factor analysis for development of asymptomatic carotid stenosis in Koreans. / Lim, Yun Jeong; Kim, Young Wook; Choe, Yeon Hyen; Ki, Chang Seok; Park, Sue Kyung.

In: Journal of Korean Medical Science, Vol. 21, No. 1, 02.2006, p. 15-19.

Research output: Contribution to journalArticle

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