Repetitive transcranial magnetic stimulation for hemispatial neglect in patients after stroke: An open-label pilot study

Jong Youb Lim, Eun Kyoung Kang, Nam Jong Paik

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Objective: To test whether multiple sessions of inhibitory low-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the left parietal area can improve hemispatial neglect after stroke. Design: An open-label design. Patients: Seven consecutive patients with hemispatial neglect after right hemispheric stroke were compared with 7 retrospectively recruited control patients. Methods: Seven patients received a session of 1 Hz rTMS to the left parietal area immediately prior to occupational therapy for 10 days. Seven control patients received only behavioural therapy. Results: Baseline values of the line bisection test and the Albert test were comparable in the two groups. The stimulation group showed a greater improvement in the line bisection test than did the control group. However, no differences were found between the two groups according to the Albert test. Conclusion: In this pilot study, low-frequency rTMS application to the non-affected left parietal area was found to be safe and to improve line bisection test, which suggests that non-invasive cortical stimulation has a potential role as an adjuvant strategy during cognitive rehabilitation training in patients with hemispatial neglect. A prospective randomized, sham-controlled study is required to determine the beneficial role of non-invasive cortical stimulation on hemispatial neglect.

Original languageEnglish
Pages (from-to)447-452
Number of pages6
JournalJournal of Rehabilitation Medicine
Volume42
Issue number5
DOIs
StatePublished - 1 May 2010

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Perceptual Disorders
Transcranial Magnetic Stimulation
Stroke
Occupational Therapy
Rehabilitation
Control Groups

Keywords

  • Brain stimulation
  • Hemispatial neglect
  • Stroke
  • Transcranial magnetic stimulation

Cite this

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Repetitive transcranial magnetic stimulation for hemispatial neglect in patients after stroke : An open-label pilot study. / Lim, Jong Youb; Kang, Eun Kyoung; Paik, Nam Jong.

In: Journal of Rehabilitation Medicine, Vol. 42, No. 5, 01.05.2010, p. 447-452.

Research output: Contribution to journalArticle

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