Rate of and risk factors for early recurrence in patients with febrile seizures

Jin Hee Jeong, Jin Hee Lee, Kyuseok Kim, You Hwan Jo, Joong Eui Rhee, Young Ho Kwak, Do Kyun Kim, Hyun Noh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: Patients with febrile seizures (FSs) are observed in emergency departments or admitted to hospitals because of the possibility of recurrence. There are no guidelines regarding the observation time for recurring FS. The aim of this study was to identify the rate, time, risk factors, and cumulative probability of early recurrence. Patients And Methods: This study was a retrospective chart review of patients visiting an emergency department with FS from January to December 2011. Early recurrence was defined as FS recurring within 7 days after the first episode. Patients were divided into 2 groups: early recurrence and nonearly recurrence. The 2 groups were compared in terms of demographics, clinical data, and laboratory findings to identify risk factors for early recurrence. The cumulative probability over time was determined. Results: In total, 228 patients were identified. The recurrence rate was 17.5% (40/228), and the median time to recurrence was 6.0 hours (interquartile range, 1.1-13.0 hours). The overall cumulative probability of early recurrence was 8.8% within 6 hours, 12.7% within 12 hours, and 15.8% within 24 hours. Most recurrences (90.0%) occurred within 24 hours of the first FS. Early recurrence occurred frequently in patients with nongeneralized-type seizures or seizures of 15-minute duration or longer. Conclusions: The majority of recurrent FSs occurred in the first 24 hours. The type and duration of seizures were significant risk factors for early recurrence.

Original languageEnglish
Pages (from-to)540-545
Number of pages6
JournalPediatric Emergency Care
Volume30
Issue number8
DOIs
StatePublished - 1 Jan 2014

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Febrile Seizures
Recurrence
Seizures
Hospital Emergency Service

Keywords

  • observation
  • recurrence
  • risk factors
  • seizure febrile

Cite this

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title = "Rate of and risk factors for early recurrence in patients with febrile seizures",
abstract = "Objective: Patients with febrile seizures (FSs) are observed in emergency departments or admitted to hospitals because of the possibility of recurrence. There are no guidelines regarding the observation time for recurring FS. The aim of this study was to identify the rate, time, risk factors, and cumulative probability of early recurrence. Patients And Methods: This study was a retrospective chart review of patients visiting an emergency department with FS from January to December 2011. Early recurrence was defined as FS recurring within 7 days after the first episode. Patients were divided into 2 groups: early recurrence and nonearly recurrence. The 2 groups were compared in terms of demographics, clinical data, and laboratory findings to identify risk factors for early recurrence. The cumulative probability over time was determined. Results: In total, 228 patients were identified. The recurrence rate was 17.5{\%} (40/228), and the median time to recurrence was 6.0 hours (interquartile range, 1.1-13.0 hours). The overall cumulative probability of early recurrence was 8.8{\%} within 6 hours, 12.7{\%} within 12 hours, and 15.8{\%} within 24 hours. Most recurrences (90.0{\%}) occurred within 24 hours of the first FS. Early recurrence occurred frequently in patients with nongeneralized-type seizures or seizures of 15-minute duration or longer. Conclusions: The majority of recurrent FSs occurred in the first 24 hours. The type and duration of seizures were significant risk factors for early recurrence.",
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Rate of and risk factors for early recurrence in patients with febrile seizures. / Jeong, Jin Hee; Lee, Jin Hee; Kim, Kyuseok; Jo, You Hwan; Rhee, Joong Eui; Kwak, Young Ho; Kim, Do Kyun; Noh, Hyun.

In: Pediatric Emergency Care, Vol. 30, No. 8, 01.01.2014, p. 540-545.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Rate of and risk factors for early recurrence in patients with febrile seizures

AU - Jeong, Jin Hee

AU - Lee, Jin Hee

AU - Kim, Kyuseok

AU - Jo, You Hwan

AU - Rhee, Joong Eui

AU - Kwak, Young Ho

AU - Kim, Do Kyun

AU - Noh, Hyun

PY - 2014/1/1

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N2 - Objective: Patients with febrile seizures (FSs) are observed in emergency departments or admitted to hospitals because of the possibility of recurrence. There are no guidelines regarding the observation time for recurring FS. The aim of this study was to identify the rate, time, risk factors, and cumulative probability of early recurrence. Patients And Methods: This study was a retrospective chart review of patients visiting an emergency department with FS from January to December 2011. Early recurrence was defined as FS recurring within 7 days after the first episode. Patients were divided into 2 groups: early recurrence and nonearly recurrence. The 2 groups were compared in terms of demographics, clinical data, and laboratory findings to identify risk factors for early recurrence. The cumulative probability over time was determined. Results: In total, 228 patients were identified. The recurrence rate was 17.5% (40/228), and the median time to recurrence was 6.0 hours (interquartile range, 1.1-13.0 hours). The overall cumulative probability of early recurrence was 8.8% within 6 hours, 12.7% within 12 hours, and 15.8% within 24 hours. Most recurrences (90.0%) occurred within 24 hours of the first FS. Early recurrence occurred frequently in patients with nongeneralized-type seizures or seizures of 15-minute duration or longer. Conclusions: The majority of recurrent FSs occurred in the first 24 hours. The type and duration of seizures were significant risk factors for early recurrence.

AB - Objective: Patients with febrile seizures (FSs) are observed in emergency departments or admitted to hospitals because of the possibility of recurrence. There are no guidelines regarding the observation time for recurring FS. The aim of this study was to identify the rate, time, risk factors, and cumulative probability of early recurrence. Patients And Methods: This study was a retrospective chart review of patients visiting an emergency department with FS from January to December 2011. Early recurrence was defined as FS recurring within 7 days after the first episode. Patients were divided into 2 groups: early recurrence and nonearly recurrence. The 2 groups were compared in terms of demographics, clinical data, and laboratory findings to identify risk factors for early recurrence. The cumulative probability over time was determined. Results: In total, 228 patients were identified. The recurrence rate was 17.5% (40/228), and the median time to recurrence was 6.0 hours (interquartile range, 1.1-13.0 hours). The overall cumulative probability of early recurrence was 8.8% within 6 hours, 12.7% within 12 hours, and 15.8% within 24 hours. Most recurrences (90.0%) occurred within 24 hours of the first FS. Early recurrence occurred frequently in patients with nongeneralized-type seizures or seizures of 15-minute duration or longer. Conclusions: The majority of recurrent FSs occurred in the first 24 hours. The type and duration of seizures were significant risk factors for early recurrence.

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