Protein Degradation

R. John Mayer, Aaron Ciechanover, Martin Rechsteiner

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

9 Citations (Scopus)

Abstract

The second volume in a new series dedicated to protein degradation, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway. Drawing on the combined knowledge of the world's leading protein degradation experts, this handy reference compiles information on the proteasome-mediated degradation steps of the ubiquitin pathway. In addition to proteasomal function and regulation, it also presents the latest results on novel members of the ubiquitin superfamily and their role in cellular regulation. Further volumes in the series cover the function of ubiquitin-protein ligases, and the roles of the ubiquitin pathway in regulating key cellular processes, as well as its pathophysiological disease states. Required reading for molecular biologists, cell biologists and physiologists with an interest in protein degradation.

Original languageEnglish
Title of host publicationThe Ubiquitin-Proteasome System
PublisherWiley-VCH
Pages1-286
Number of pages286
Volume2
ISBN (Print)3527311300, 9783527311309
DOIs
StatePublished - 10 Jan 2008

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Ubiquitin
Proteolysis
Degradation
Proteins
Ubiquitin-Protein Ligases
Proteasome Endopeptidase Complex
Reading

Cite this

Mayer, R. J., Ciechanover, A., & Rechsteiner, M. (2008). Protein Degradation. In The Ubiquitin-Proteasome System (Vol. 2, pp. 1-286). Wiley-VCH. https://doi.org/10.1002/9783527620210
Mayer, R. John ; Ciechanover, Aaron ; Rechsteiner, Martin. / Protein Degradation. The Ubiquitin-Proteasome System. Vol. 2 Wiley-VCH, 2008. pp. 1-286
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Mayer, RJ, Ciechanover, A & Rechsteiner, M 2008, Protein Degradation. in The Ubiquitin-Proteasome System. vol. 2, Wiley-VCH, pp. 1-286. https://doi.org/10.1002/9783527620210

Protein Degradation. / Mayer, R. John; Ciechanover, Aaron; Rechsteiner, Martin.

The Ubiquitin-Proteasome System. Vol. 2 Wiley-VCH, 2008. p. 1-286.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

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Mayer RJ, Ciechanover A, Rechsteiner M. Protein Degradation. In The Ubiquitin-Proteasome System. Vol. 2. Wiley-VCH. 2008. p. 1-286 https://doi.org/10.1002/9783527620210