Placental deposition of C-reactive protein is a common feature of human pregnancy

E. N. Kim, Bohyun Yoon, E. J. Jeon, J. B. Lee, Joon Seok Hong, J. Y. Lee, D. Hwang, K. C. Kim, J. S. Kim, C. J. Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study examined the occurrence of placental C-reactive protein (CRP) in normal pregnancy with term delivery, spontaneous preterm delivery (sPTD), preeclampsia, and miscarriage. CRP immunoreactivity was detected in the syncytiotrophoblast. The immunopositive rate was significantly higher in sPTD than preeclampsia. The CRP immunopositive rate was also higher in acute chorioamnionitis than those without and showed a good correlation with the maternal serum CRP concentration. CRP mRNA expression was not detected in human and mouse placentas or choriocarcinoma cells. CRP may play a role in the pathological and physiological states of pregnancy.

Original languageEnglish
Pages (from-to)704-707
Number of pages4
JournalPlacenta
Volume36
Issue number6
DOIs
StatePublished - 1 Jun 2015

Fingerprint

C-Reactive Protein
Pregnancy
Pre-Eclampsia
Pregnancy Proteins
Chorioamnionitis
Choriocarcinoma
Trophoblasts
Spontaneous Abortion
Placenta
Blood Proteins
Mothers
Messenger RNA

Keywords

  • C-reactive protein
  • Immunohistochemistry
  • Placenta
  • Trophoblast

Cite this

Kim, E. N. ; Yoon, Bohyun ; Jeon, E. J. ; Lee, J. B. ; Hong, Joon Seok ; Lee, J. Y. ; Hwang, D. ; Kim, K. C. ; Kim, J. S. ; Kim, C. J. / Placental deposition of C-reactive protein is a common feature of human pregnancy. In: Placenta. 2015 ; Vol. 36, No. 6. pp. 704-707.
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author = "Kim, {E. N.} and Bohyun Yoon and Jeon, {E. J.} and Lee, {J. B.} and Hong, {Joon Seok} and Lee, {J. Y.} and D. Hwang and Kim, {K. C.} and Kim, {J. S.} and Kim, {C. J.}",
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Kim, EN, Yoon, B, Jeon, EJ, Lee, JB, Hong, JS, Lee, JY, Hwang, D, Kim, KC, Kim, JS & Kim, CJ 2015, 'Placental deposition of C-reactive protein is a common feature of human pregnancy', Placenta, vol. 36, no. 6, pp. 704-707. https://doi.org/10.1016/j.placenta.2015.03.006

Placental deposition of C-reactive protein is a common feature of human pregnancy. / Kim, E. N.; Yoon, Bohyun; Jeon, E. J.; Lee, J. B.; Hong, Joon Seok; Lee, J. Y.; Hwang, D.; Kim, K. C.; Kim, J. S.; Kim, C. J.

In: Placenta, Vol. 36, No. 6, 01.06.2015, p. 704-707.

Research output: Contribution to journalArticle

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T1 - Placental deposition of C-reactive protein is a common feature of human pregnancy

AU - Kim, E. N.

AU - Yoon, Bohyun

AU - Jeon, E. J.

AU - Lee, J. B.

AU - Hong, Joon Seok

AU - Lee, J. Y.

AU - Hwang, D.

AU - Kim, K. C.

AU - Kim, J. S.

AU - Kim, C. J.

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