Perivascular epithelioid cell tumor in the stomach

Sun Ah Shin, Jiwoon Choi, Kyung Chul Moon, Woo Ho Kim

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Perivascular epithelioid cell tumors or PEComas can arise in any location in the body. However, a limited number of cases of gastric PEComa have been reported. We present two cases of gastric PEComas. The first case involved a 62-year-old woman who presented with a 4.2 cm gastric subepithelial mass in the prepyloric antrum, and the second case involved a 67-year-old man with a 5.0 cm mass slightly below the gastroesophageal junction. Microscopic examination revealed that both tumors were composed of perivascular epithelioid cells that were immunoreactive for melanocytic and smooth muscle markers. Prior to surgery, the clinical impression of both tumors was gastrointestinal stromal tumor (GIST), and the second case was erroneously diagnosed as GIST even after microscopic examination. Although gastric PEComa is a very rare neoplasm, it should be considered in the differential diagnosis of gastric submucosal lesions.

Original languageEnglish
Pages (from-to)428-432
Number of pages5
JournalJournal of Pathology and Translational Medicine
Volume51
Issue number4
DOIs
StatePublished - 1 Jul 2017

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Perivascular Epithelioid Cell Neoplasms
Stomach
Gastrointestinal Stromal Tumors
Esophagogastric Junction
Epithelioid Cells
Neoplasms
Smooth Muscle
Differential Diagnosis

Keywords

  • Gastrointestinal stromal tumors
  • HMB-45 protein, human
  • MART-1 antigen
  • Perivascular epithelioid cell neoplasms
  • Stomach neoplasms

Cite this

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title = "Perivascular epithelioid cell tumor in the stomach",
abstract = "Perivascular epithelioid cell tumors or PEComas can arise in any location in the body. However, a limited number of cases of gastric PEComa have been reported. We present two cases of gastric PEComas. The first case involved a 62-year-old woman who presented with a 4.2 cm gastric subepithelial mass in the prepyloric antrum, and the second case involved a 67-year-old man with a 5.0 cm mass slightly below the gastroesophageal junction. Microscopic examination revealed that both tumors were composed of perivascular epithelioid cells that were immunoreactive for melanocytic and smooth muscle markers. Prior to surgery, the clinical impression of both tumors was gastrointestinal stromal tumor (GIST), and the second case was erroneously diagnosed as GIST even after microscopic examination. Although gastric PEComa is a very rare neoplasm, it should be considered in the differential diagnosis of gastric submucosal lesions.",
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Perivascular epithelioid cell tumor in the stomach. / Shin, Sun Ah; Choi, Jiwoon; Moon, Kyung Chul; Kim, Woo Ho.

In: Journal of Pathology and Translational Medicine, Vol. 51, No. 4, 01.07.2017, p. 428-432.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Shin, Sun Ah

AU - Choi, Jiwoon

AU - Moon, Kyung Chul

AU - Kim, Woo Ho

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N2 - Perivascular epithelioid cell tumors or PEComas can arise in any location in the body. However, a limited number of cases of gastric PEComa have been reported. We present two cases of gastric PEComas. The first case involved a 62-year-old woman who presented with a 4.2 cm gastric subepithelial mass in the prepyloric antrum, and the second case involved a 67-year-old man with a 5.0 cm mass slightly below the gastroesophageal junction. Microscopic examination revealed that both tumors were composed of perivascular epithelioid cells that were immunoreactive for melanocytic and smooth muscle markers. Prior to surgery, the clinical impression of both tumors was gastrointestinal stromal tumor (GIST), and the second case was erroneously diagnosed as GIST even after microscopic examination. Although gastric PEComa is a very rare neoplasm, it should be considered in the differential diagnosis of gastric submucosal lesions.

AB - Perivascular epithelioid cell tumors or PEComas can arise in any location in the body. However, a limited number of cases of gastric PEComa have been reported. We present two cases of gastric PEComas. The first case involved a 62-year-old woman who presented with a 4.2 cm gastric subepithelial mass in the prepyloric antrum, and the second case involved a 67-year-old man with a 5.0 cm mass slightly below the gastroesophageal junction. Microscopic examination revealed that both tumors were composed of perivascular epithelioid cells that were immunoreactive for melanocytic and smooth muscle markers. Prior to surgery, the clinical impression of both tumors was gastrointestinal stromal tumor (GIST), and the second case was erroneously diagnosed as GIST even after microscopic examination. Although gastric PEComa is a very rare neoplasm, it should be considered in the differential diagnosis of gastric submucosal lesions.

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