Neuronavigation-guided repetitive transcranial magnetic stimulation for aphasia

Woo Jin Kim, Soo Jung Hahn, Won Seok Kim, Nam Jong Paik

Research output: Contribution to journalArticle

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is widely used for several neurological conditions, as it has gained acknowledgement for its potential therapeutic effects. Brain excitability is non-invasively modulated by rTMS, and rTMS to the language areas has proved its potential effects on treatment of aphasia. In our protocol, we aim to artificially induce virtual aphasia in healthy subjects by inhibiting Brodmann area 44 and 45 using neuronavigational TMS (nTMS), and F3 of the International 10-20 EEG system for conventional TMS (cTMS). To measure the degree of aphasia, changes in reaction time to a picture naming task pre- and post-stimulation are measured and compare the delay in reaction time between nTMS and cTMS. Accuracy of the two TMS stimulation methods is compared by averaging the Talairach coordinates of the target and the actual stimulation. Consistency of stimulation is demonstrated by the error range from the target. The purpose of this study is to demonstrate use of nTMS and to describe the benefits and limitations of the nTMS compared to those of cTMS.

Original languageEnglish
Article numbere53345
JournalJournal of Visualized Experiments
Volume2016
Issue number111
DOIs
StatePublished - 6 May 2016

Fingerprint

Neuronavigation
Transcranial Magnetic Stimulation
Aphasia
Electroencephalography
Brain
Therapeutic Uses
Healthy Volunteers
Language
Therapeutics

Keywords

  • Aphasia
  • Behavior
  • Broca
  • Issue 111
  • Neuromodulation
  • Neuronavigation
  • Stroke
  • Transcranial magnetic stimulation

Cite this

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Neuronavigation-guided repetitive transcranial magnetic stimulation for aphasia. / Kim, Woo Jin; Hahn, Soo Jung; Kim, Won Seok; Paik, Nam Jong.

In: Journal of Visualized Experiments, Vol. 2016, No. 111, e53345, 06.05.2016.

Research output: Contribution to journalArticle

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