Nanoelectrokinetic Selective Preconcentration Based on Ion Concentration Polarization

Jihye Choi; Seongho Baek; Hee Chan Kim; Jong Hee Chae; Youngil Koh; Sang Woo Seo; Hyomin Lee; Sung Jae Kim

doi:10.1007/s13206-020-4109-3

Nanoelectrokinetic Selective Preconcentration Based on Ion Concentration Polarization

Jihye Choi, Seongho Baek, Hee Chan Kim, Jong Hee Chae, Youngil Koh, Sang Woo Seo, Hyomin Lee, Sung Jae Kim

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Nanoscale electrokinetic phenomenon called ion concentration polarization (ICP) has opened a new era in bio- and chemical-analysis platform due to its high efficiency and easy sample handling. In this review, the most recent advancements of selective preconcentration process using ICP were introduced. The flux balances of charged analytes were theoretically analyzed so that the behavior and the shape of preconcentrated plug were categorized into stacking/propagating and dumbbell/plug, respectively. The experimental demonstrations of these features were also given to verify the modeling. Furthermore, promising applications based on the analysis were described in this review. Lastly, future research direction would be suggested by elucidating pros and cons of ICP process.

Original language	English
Pages (from-to)	100-109
Number of pages	10
Journal	Biochip Journal
Volume	14
Issue number	1
DOIs	https://doi.org/10.1007/s13206-020-4109-3
State	Published - 1 Mar 2020

Bibliographical note

Publisher Copyright:
© 2020, The Korean BioChip Society and Springer.

Keywords

Biomolecules
Critical mobility
Driftless preconcentration
Ion concentration polarization
Nanoelectrokinetics
Perm-selective ion transportation
Selective preconcentration

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10.1007/s13206-020-4109-3

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title = "Nanoelectrokinetic Selective Preconcentration Based on Ion Concentration Polarization",

abstract = "Nanoscale electrokinetic phenomenon called ion concentration polarization (ICP) has opened a new era in bio- and chemical-analysis platform due to its high efficiency and easy sample handling. In this review, the most recent advancements of selective preconcentration process using ICP were introduced. The flux balances of charged analytes were theoretically analyzed so that the behavior and the shape of preconcentrated plug were categorized into stacking/propagating and dumbbell/plug, respectively. The experimental demonstrations of these features were also given to verify the modeling. Furthermore, promising applications based on the analysis were described in this review. Lastly, future research direction would be suggested by elucidating pros and cons of ICP process.",

keywords = "Biomolecules, Critical mobility, Driftless preconcentration, Ion concentration polarization, Nanoelectrokinetics, Perm-selective ion transportation, Selective preconcentration",

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AU - Choi, Jihye

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AU - Chae, Jong Hee

AU - Koh, Youngil

AU - Seo, Sang Woo

AU - Lee, Hyomin

AU - Kim, Sung Jae

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KW - Biomolecules

KW - Critical mobility

KW - Driftless preconcentration

KW - Ion concentration polarization

KW - Nanoelectrokinetics

KW - Perm-selective ion transportation

KW - Selective preconcentration

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Nanoelectrokinetic Selective Preconcentration Based on Ion Concentration Polarization

Abstract

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Keywords

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