Abstract
Radical cystectomy and urinary diversion have been the standard treatment for muscle-invasive bladder cancer. However, radical cystectomy is complicated, and simultaneous surgery involves the genitourinary tract, gastrointestinal tract, and pelvic organs. Consequently, surgery-related complications frequently occur. However, the morbidity and mortality after radical cystectomy varies widely according to the reports. Therefore, organized systematic reporting system is necessary for comparing data from different hospitals and surgical techniques or from different patients. Today, the most common complications after radical cystectomy are bowel obstruction followed by infection such as acute pyelonephritis. Meanwhile, the main causes of mortality involved acute cardiopulmonary events, such as myocardial infarction or pulmonary embolism. Sepsis following an infectious condition, originating from intestinal anastomotic or urinary leakage, was also associated with mortality. Survival after radical cystectomy is mainly determined by postoperative features. Postoperative pathological tumor stage, lymph node status, and margin status are the most valuable predictors of survival outcomes following cystectomy. Additional variables that are associated with cancer-specific survival are actively investigated.
Original language | English |
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Title of host publication | Bladder Cancer |
Publisher | Elsevier Inc. |
Pages | 439-449 |
Number of pages | 11 |
ISBN (Electronic) | 9780128099407 |
ISBN (Print) | 9780128099391 |
DOIs | |
State | Published - 1 Jan 2018 |
Keywords
- Bladder cancer
- Morbidity
- Mortality
- Radical cystectomy
- Survival