Middle east respiratory syndrome: What we learned from the 2015 outbreak in the republic of Korea

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Abstract

Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERS-CoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERS-CoV.

Original languageEnglish
Pages (from-to)233-246
Number of pages14
JournalKorean Journal of Internal Medicine
Volume33
Issue number2
DOIs
StatePublished - Mar 2018

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Coronavirus Infections
Republic of Korea
Disease Outbreaks
Korea
Virology
Pneumonia
Epidemiology
Middle East Respiratory Syndrome Coronavirus

Keywords

  • Coronavirus
  • Coronavirus infections
  • Disease outbreaks
  • Korea
  • Middle East respiratory syndrome coronavirus

Cite this

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title = "Middle east respiratory syndrome: What we learned from the 2015 outbreak in the republic of Korea",
abstract = "Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERS-CoV involved 186 cases, including 38 fatalities. A total of 83{\%} of transmission events were due to five superspreaders, and 44{\%} of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERS-CoV.",
keywords = "Coronavirus, Coronavirus infections, Disease outbreaks, Korea, Middle East respiratory syndrome coronavirus",
author = "Oh, {Myoung Don} and Park, {Wan Beom} and Park, {Sang Won} and Choe, {Pyoeng Gyun} and Bang, {Ji Hwan} and Song, {Kyoung Ho} and Kim, {Eu Suk} and Kim, {Hong Bin} and Kim, {Nam Joong}",
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AU - Oh, Myoung Don

AU - Park, Wan Beom

AU - Park, Sang Won

AU - Choe, Pyoeng Gyun

AU - Bang, Ji Hwan

AU - Song, Kyoung Ho

AU - Kim, Eu Suk

AU - Kim, Hong Bin

AU - Kim, Nam Joong

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AB - Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERS-CoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERS-CoV.

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KW - Disease outbreaks

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