Maternal exposure to particulate matter during pregnancy and adverse birth outcomes in the Republic of Korea

Yu Jin Kim, In Gyu Song, Kyoung Nam Kim, Min Sun Kim, Sung Hoon Chung, Yong Sung Choi, Chong Woo Bae

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Air pollution has become a global concern due to its association with numerous health effects. We aimed to assess associations between birth outcomes in Korea, such as preterm births and birth weight in term infants, and particulate matter < 10 µm (PM 10 ). Records from 1,742,183 single births in 2010-2013 were evaluated. Mean PM 10 concentrations during pregnancy were calculated and matched to birth data by registered regions. We analyzed the frequency of birth outcomes between groups using WHO criteria for PM 10 concentrations with effect sizes estimated using multivariate logistic regression. Women exposed to PM 10 > 70 µg/m 3 during pregnancy had a higher rate of preterm births than women exposed to PM 10 ≤ 70 µg/m 3 (7.4% vs. 4.7%, P < 0.001; adjusted odds ratio (aOR) 1.570; 95% confidence interval (CI): 1.487-1.656). The rate of low birth weight in term infants increased when women were exposed to PM 10 > 70 µg/m 3 (1.9% vs. 1.7%, P = 0.278), but this difference was not statistically significant (aOR 1.060, 95% CI: 0.953-1.178). In conclusion, PM 10 exposure > 70 µg/m 3 was associated with preterm births. Further studies are needed to explore the pathophysiologic mechanisms and guide policy development to prevent future adverse effects on birth outcomes.

Original languageEnglish
Article number633
JournalInternational journal of environmental research and public health
Volume16
Issue number4
DOIs
StatePublished - 2 Feb 2019

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Maternal Exposure
Republic of Korea
Particulate Matter
Premature Birth
Parturition
Pregnancy
Policy Making
Air Pollution
Korea
Birth Weight
Health

Keywords

  • Maternal exposure
  • Particulate matter
  • Preterm birth

Cite this

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title = "Maternal exposure to particulate matter during pregnancy and adverse birth outcomes in the Republic of Korea",
abstract = "Air pollution has become a global concern due to its association with numerous health effects. We aimed to assess associations between birth outcomes in Korea, such as preterm births and birth weight in term infants, and particulate matter < 10 µm (PM 10 ). Records from 1,742,183 single births in 2010-2013 were evaluated. Mean PM 10 concentrations during pregnancy were calculated and matched to birth data by registered regions. We analyzed the frequency of birth outcomes between groups using WHO criteria for PM 10 concentrations with effect sizes estimated using multivariate logistic regression. Women exposed to PM 10 > 70 µg/m 3 during pregnancy had a higher rate of preterm births than women exposed to PM 10 ≤ 70 µg/m 3 (7.4{\%} vs. 4.7{\%}, P < 0.001; adjusted odds ratio (aOR) 1.570; 95{\%} confidence interval (CI): 1.487-1.656). The rate of low birth weight in term infants increased when women were exposed to PM 10 > 70 µg/m 3 (1.9{\%} vs. 1.7{\%}, P = 0.278), but this difference was not statistically significant (aOR 1.060, 95{\%} CI: 0.953-1.178). In conclusion, PM 10 exposure > 70 µg/m 3 was associated with preterm births. Further studies are needed to explore the pathophysiologic mechanisms and guide policy development to prevent future adverse effects on birth outcomes.",
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Maternal exposure to particulate matter during pregnancy and adverse birth outcomes in the Republic of Korea. / Kim, Yu Jin; Song, In Gyu; Kim, Kyoung Nam; Kim, Min Sun; Chung, Sung Hoon; Choi, Yong Sung; Bae, Chong Woo.

In: International journal of environmental research and public health, Vol. 16, No. 4, 633, 02.02.2019.

Research output: Contribution to journalArticle

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T1 - Maternal exposure to particulate matter during pregnancy and adverse birth outcomes in the Republic of Korea

AU - Kim, Yu Jin

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AU - Kim, Min Sun

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AU - Choi, Yong Sung

AU - Bae, Chong Woo

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