Maternal and fetal exposure to bisphenol A in Korea

Young Joo Lee, Heui Young Ryu, Hyun Kyung Kim, Chung Sik Min, Jin Hee Lee, Eunhee Kim, Bong Hyun Nam, Joo Hong Park, Jin Young Jung, Dong Deuk Jang, Eun Young Park, Kwan Hee Lee, Jin Young Ma, Hey Sung Won, Moon Whan Im, Jong Han Leem, Yun Chul Hong, Hae Seong Yoon

Research output: Contribution to journalArticle

135 Citations (Scopus)

Abstract

Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 μg/L in pregnant women and from non-detectable to 8.86 μg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p < 0.05).

Original languageEnglish
Pages (from-to)413-419
Number of pages7
JournalReproductive Toxicology
Volume25
Issue number4
DOIs
StatePublished - 1 Aug 2008

Fingerprint

Maternal Exposure
Korea
Pregnant Women
Blood
Umbilical Cord
Endocrine disrupters
Mothers
bisphenol A
Fetal Blood
Fetus
Pregnancy

Keywords

  • Biomonitoring
  • Bisphenol A
  • Fetus
  • Human exposure
  • Korea
  • Maternal serum
  • Pregnant woman
  • Umbilical cord blood

Cite this

Lee, Y. J., Ryu, H. Y., Kim, H. K., Min, C. S., Lee, J. H., Kim, E., ... Yoon, H. S. (2008). Maternal and fetal exposure to bisphenol A in Korea. Reproductive Toxicology, 25(4), 413-419. https://doi.org/10.1016/j.reprotox.2008.05.058
Lee, Young Joo ; Ryu, Heui Young ; Kim, Hyun Kyung ; Min, Chung Sik ; Lee, Jin Hee ; Kim, Eunhee ; Nam, Bong Hyun ; Park, Joo Hong ; Jung, Jin Young ; Jang, Dong Deuk ; Park, Eun Young ; Lee, Kwan Hee ; Ma, Jin Young ; Won, Hey Sung ; Im, Moon Whan ; Leem, Jong Han ; Hong, Yun Chul ; Yoon, Hae Seong. / Maternal and fetal exposure to bisphenol A in Korea. In: Reproductive Toxicology. 2008 ; Vol. 25, No. 4. pp. 413-419.
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abstract = "Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 μg/L in pregnant women and from non-detectable to 8.86 μg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p < 0.05).",
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Lee, YJ, Ryu, HY, Kim, HK, Min, CS, Lee, JH, Kim, E, Nam, BH, Park, JH, Jung, JY, Jang, DD, Park, EY, Lee, KH, Ma, JY, Won, HS, Im, MW, Leem, JH, Hong, YC & Yoon, HS 2008, 'Maternal and fetal exposure to bisphenol A in Korea', Reproductive Toxicology, vol. 25, no. 4, pp. 413-419. https://doi.org/10.1016/j.reprotox.2008.05.058

Maternal and fetal exposure to bisphenol A in Korea. / Lee, Young Joo; Ryu, Heui Young; Kim, Hyun Kyung; Min, Chung Sik; Lee, Jin Hee; Kim, Eunhee; Nam, Bong Hyun; Park, Joo Hong; Jung, Jin Young; Jang, Dong Deuk; Park, Eun Young; Lee, Kwan Hee; Ma, Jin Young; Won, Hey Sung; Im, Moon Whan; Leem, Jong Han; Hong, Yun Chul; Yoon, Hae Seong.

In: Reproductive Toxicology, Vol. 25, No. 4, 01.08.2008, p. 413-419.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Maternal and fetal exposure to bisphenol A in Korea

AU - Lee, Young Joo

AU - Ryu, Heui Young

AU - Kim, Hyun Kyung

AU - Min, Chung Sik

AU - Lee, Jin Hee

AU - Kim, Eunhee

AU - Nam, Bong Hyun

AU - Park, Joo Hong

AU - Jung, Jin Young

AU - Jang, Dong Deuk

AU - Park, Eun Young

AU - Lee, Kwan Hee

AU - Ma, Jin Young

AU - Won, Hey Sung

AU - Im, Moon Whan

AU - Leem, Jong Han

AU - Hong, Yun Chul

AU - Yoon, Hae Seong

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AB - Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 μg/L in pregnant women and from non-detectable to 8.86 μg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p < 0.05).

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KW - Bisphenol A

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KW - Pregnant woman

KW - Umbilical cord blood

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U2 - 10.1016/j.reprotox.2008.05.058

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M3 - Article

C2 - 18577445

AN - SCOPUS:47249103294

VL - 25

SP - 413

EP - 419

JO - Reproductive Toxicology

JF - Reproductive Toxicology

SN - 0890-6238

IS - 4

ER -

Lee YJ, Ryu HY, Kim HK, Min CS, Lee JH, Kim E et al. Maternal and fetal exposure to bisphenol A in Korea. Reproductive Toxicology. 2008 Aug 1;25(4):413-419. https://doi.org/10.1016/j.reprotox.2008.05.058