TY - JOUR
T1 - Lipid Management in Korean People With Type 2 Diabetes Mellitus
T2 - Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
AU - Yang, Ye Seul
AU - Kim, Hack Lyoung
AU - Kim, Sang Hyun
AU - Moon, Min Kyong
N1 - Publisher Copyright:
© 2023 The Korean Society of Lipid and Atherosclerosis.
PY - 2023/1
Y1 - 2023/1
N2 - Dyslipidemia in patients with diabetes is an important treatment target as a modifiable risk factor for cardiovascular disease (CVD). Although the primary treatment goal for dyslipidemia is to control low-density lipoprotein cholesterol (LDL-C), achieving this goal remains suboptimal according to recent studies. It is important to set the target goal for LDL-C control based on an accurate risk assessment for CVD. Here, we summarize the latest evidence on lipid management in patients with diabetes and present a consensus of the Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis on the treatment goals of LDL-C according to the duration of diabetes, presence of CVD, target organ damage, or major cardiovascular risk factors. In patients with type 2 diabetes mellitus (T2DM) and CVD, an LDL-C goal of <55 mg/dL and a reduction in LDL-C level by 50% or more from the baseline is recommended. For the primary prevention of CVD in patients with T2DM with a duration of diabetes ≥10 years, major cardiovascular risk factors, or target organ damage, an LDL-C goal of <70 mg/dL is recommended. In patients with T2DM with a duration of diabetes <10 years and no major cardiovascular risk factors, an LDL-C goal of <100 mg/dL is recommended.
AB - Dyslipidemia in patients with diabetes is an important treatment target as a modifiable risk factor for cardiovascular disease (CVD). Although the primary treatment goal for dyslipidemia is to control low-density lipoprotein cholesterol (LDL-C), achieving this goal remains suboptimal according to recent studies. It is important to set the target goal for LDL-C control based on an accurate risk assessment for CVD. Here, we summarize the latest evidence on lipid management in patients with diabetes and present a consensus of the Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis on the treatment goals of LDL-C according to the duration of diabetes, presence of CVD, target organ damage, or major cardiovascular risk factors. In patients with type 2 diabetes mellitus (T2DM) and CVD, an LDL-C goal of <55 mg/dL and a reduction in LDL-C level by 50% or more from the baseline is recommended. For the primary prevention of CVD in patients with T2DM with a duration of diabetes ≥10 years, major cardiovascular risk factors, or target organ damage, an LDL-C goal of <70 mg/dL is recommended. In patients with T2DM with a duration of diabetes <10 years and no major cardiovascular risk factors, an LDL-C goal of <100 mg/dL is recommended.
KW - Cholesterol, LDL
KW - Diabetes mellitus, type 2
KW - Dyslipidemias
KW - Guideline
KW - Hydroxymethylglutaryl-CoA reductase inhibitors
UR - http://www.scopus.com/inward/record.url?scp=85147273340&partnerID=8YFLogxK
U2 - 10.12997/jla.2023.12.1.12
DO - 10.12997/jla.2023.12.1.12
M3 - Review article
AN - SCOPUS:85147273340
SN - 2287-2892
VL - 12
SP - 12
EP - 22
JO - Journal of Lipid and Atherosclerosis
JF - Journal of Lipid and Atherosclerosis
IS - 1
ER -