Lesion characterization using vessel permeability map to new blood pool contrast agent calculated from dynamic magnetic resonance images

Soojeong Kim, Jong Hyo Kim, Woo Kyung Moon, Byoung Goo Min

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations

Abstract

Use of contrast enhancement in conjunction with magnetic resonance (MR) imaging provides a means to evaluate tissue function, as well as morphology. Moreover, physiologic properties derived from kinetic analysis of dynamic contrast-enhanced data can improve the specificity of MR examinations. In this study, quantitative analysis of microvascular characteristics based on dynamic MR imaging were performed both for malignant and benign lesions using two types of contrast agents (CAs). A new MR macromolecular contrast medium (MMCM), 24 gadolinium-tetraazacyclododecanetetraacetic acid (DOTA)-dendrimer, was found to have a greater ability to distinguish benign from malignant lesions. When a blood pool agent was used, permeability differences in the two types of lesions were the most significant findings among all parameters considered.

Original languageEnglish
Pages (from-to)193-195
Number of pages3
JournalJournal of Digital Imaging
Volume13
Issue number2 SUPPL. 1
DOIs
StatePublished - May 2000
EventSCAR 2000 - 17th Symposium for Computer Applications in Radiology 'The Electronic Practice: Radiology and the Enterprise' - Philadelphia, PA, USA
Duration: 3 Jun 20006 Jun 2000

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