@inproceedings{9a31e91e5681429d927b6f309d629f48,
title = "Laminated cubic biodegradable polymer structures for bacteria-based, robotic drug delivery",
abstract = "Recently, a bacteria-based drug delivery system has been proposed to achieve effective and localized drug delivery. Researchers have shown that flagellated bacteria have a chemotactic property to tumor cells, and they can be used as an energy source for active drug delivery. Our previous results have reported that a circular droplet made by a biodegradable polymer can be used in this bacteria-based, robotic drug delivery. In this paper, using laminated cubic structures made of several layers of biodegradable polymers for bacteria-based microrobot is proposed. The structures are made by laminating polymer layers and then, micromachining them using a deep X-ray synchrotron radiation into 40 μm x 40 μm x 40 μm cubes. The cubic structure is more beneficial in attaching bacteria in only selective surface directions than a circular structure, and in controlling the volume of drugs to be encapsulated with the outer polymer layer.",
keywords = "Bacteria, Biodegradable polymer, Drug delivery system, Lamination, Microfabrication, X-ray synchrotron radiation",
author = "Yoo, {Hyung Jung} and Sangmin Lee and Ahn, {Jae Hyun} and Hong, {Seok Jun} and Minjae Lee and Seo, {Jong Mo} and Kim, {Tae You} and Kim, {Sung Jae} and Cho, {Dong Il Dan}",
year = "2012",
doi = "10.1117/12.2000219",
language = "English",
isbn = "9780819492920",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Nanosystems in Engineering and Medicine",
note = "Nanosystems in Engineering and Medicine ; Conference date: 10-09-2012 Through 12-09-2012",
}