Intranodal palisaded myofibroblastoma with desmin expression - A brief case report

Dong Chul Kim, Tae Hoon Kang, Min Ah Kim, Yoon Kyung Jeon

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.

Original languageEnglish
Pages (from-to)263-265
Number of pages3
JournalKorean Journal of Pathology
Volume43
Issue number3
DOIs
StatePublished - 1 Jun 2009

Fingerprint

Muscle Tissue Neoplasms
Desmin
Neoplasms
Lymph Nodes
Hemorrhage
Republic of Korea
S100 Proteins
Groin
Vimentin
Smooth Muscle
Actins
Cell Proliferation

Keywords

  • Lymph node
  • Mesenchyme
  • Myofibroblastoma

Cite this

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title = "Intranodal palisaded myofibroblastoma with desmin expression - A brief case report",
abstract = "Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.",
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Intranodal palisaded myofibroblastoma with desmin expression - A brief case report. / Kim, Dong Chul; Kang, Tae Hoon; Kim, Min Ah; Jeon, Yoon Kyung.

In: Korean Journal of Pathology, Vol. 43, No. 3, 01.06.2009, p. 263-265.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Intranodal palisaded myofibroblastoma with desmin expression - A brief case report

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AU - Kang, Tae Hoon

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AU - Jeon, Yoon Kyung

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AB - Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.

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