Increasing prevalence of antimicrobial resistance in urinary tract infections of neurological patients, Seoul, South Korea, 2007–2016

Hye Rim Shin, Jangsup Moon, Han Sang Lee, Seon Jae Ahn, Tae Joon Kim, Jin Sun Jun, Jun Sang Sunwoo, Soon-Tae Lee, Kun-Hwa Jung, Kyung Il Park, Ki-Young Jung, Manho Kim, Sang Kun Lee, Kon Chu

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objectives: Urinary tract infection (UTI) is a common medical complication experienced by patients with neurologic diseases. In this study, we established the microbial etiologies of UTI, and resistances to antibiotics in UTI as well as determining which appropriate empirical antibiotics should be used to treat UTI in neurological patients. Designs and methods: We retrospectively reviewed microbial etiologies and antimicrobial resistance among patients experiencing UTI events in the neurology ward of Seoul National University Hospital from 2007 to 2016. Results: The total number of UTI events observed was 301, and Klebsiella pneumoniae was the most common pathogen observed in UTIs. But in catheter-associated UTI (CAUTI), Enterococcus species were the most prevalent pathogens. Susceptibility to commonly-prescribed antibiotics decreased over 10 years, indicating increased antibiotic resistance in pathogens associated with UTI. ESBL-producing K. pneumoniae increased significantly, while increases of MDR K. pneumoniae, ESBL-producing E. coli, and VRE were not observed. Conclusions: The worldwide trend of increasing drug-resistant pathogens should be considered, and further studies on antibiotics resistance in UTI are needed. These data will greatly assist physicians when they select antibiotics to treat UTIs in neurological patients.

Original languageEnglish
Pages (from-to)109-115
Number of pages7
JournalInternational Journal of Infectious Diseases
Volume84
DOIs
StatePublished - 1 Jul 2019

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Republic of Korea
Urinary Tract Infections
Klebsiella pneumoniae
Microbial Drug Resistance
Anti-Bacterial Agents
Seoul
Catheter-Related Infections
Enterococcus
Neurology
Nervous System Diseases
Escherichia coli
Physicians

Keywords

  • Anti-bacterial agents
  • Bacterial
  • Drug resistance
  • Microbiological phenomena
  • Urinary tract infections

Cite this

@article{34af92b4cbf44cb9b5f1dc21ad14e2cf,
title = "Increasing prevalence of antimicrobial resistance in urinary tract infections of neurological patients, Seoul, South Korea, 2007–2016",
abstract = "Objectives: Urinary tract infection (UTI) is a common medical complication experienced by patients with neurologic diseases. In this study, we established the microbial etiologies of UTI, and resistances to antibiotics in UTI as well as determining which appropriate empirical antibiotics should be used to treat UTI in neurological patients. Designs and methods: We retrospectively reviewed microbial etiologies and antimicrobial resistance among patients experiencing UTI events in the neurology ward of Seoul National University Hospital from 2007 to 2016. Results: The total number of UTI events observed was 301, and Klebsiella pneumoniae was the most common pathogen observed in UTIs. But in catheter-associated UTI (CAUTI), Enterococcus species were the most prevalent pathogens. Susceptibility to commonly-prescribed antibiotics decreased over 10 years, indicating increased antibiotic resistance in pathogens associated with UTI. ESBL-producing K. pneumoniae increased significantly, while increases of MDR K. pneumoniae, ESBL-producing E. coli, and VRE were not observed. Conclusions: The worldwide trend of increasing drug-resistant pathogens should be considered, and further studies on antibiotics resistance in UTI are needed. These data will greatly assist physicians when they select antibiotics to treat UTIs in neurological patients.",
keywords = "Anti-bacterial agents, Bacterial, Drug resistance, Microbiological phenomena, Urinary tract infections",
author = "Shin, {Hye Rim} and Jangsup Moon and Lee, {Han Sang} and Ahn, {Seon Jae} and Kim, {Tae Joon} and Jun, {Jin Sun} and Sunwoo, {Jun Sang} and Soon-Tae Lee and Kun-Hwa Jung and Park, {Kyung Il} and Ki-Young Jung and Manho Kim and Lee, {Sang Kun} and Kon Chu",
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Increasing prevalence of antimicrobial resistance in urinary tract infections of neurological patients, Seoul, South Korea, 2007–2016. / Shin, Hye Rim; Moon, Jangsup; Lee, Han Sang; Ahn, Seon Jae; Kim, Tae Joon; Jun, Jin Sun; Sunwoo, Jun Sang; Lee, Soon-Tae; Jung, Kun-Hwa; Park, Kyung Il; Jung, Ki-Young; Kim, Manho; Lee, Sang Kun; Chu, Kon.

In: International Journal of Infectious Diseases, Vol. 84, 01.07.2019, p. 109-115.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Increasing prevalence of antimicrobial resistance in urinary tract infections of neurological patients, Seoul, South Korea, 2007–2016

AU - Shin, Hye Rim

AU - Moon, Jangsup

AU - Lee, Han Sang

AU - Ahn, Seon Jae

AU - Kim, Tae Joon

AU - Jun, Jin Sun

AU - Sunwoo, Jun Sang

AU - Lee, Soon-Tae

AU - Jung, Kun-Hwa

AU - Park, Kyung Il

AU - Jung, Ki-Young

AU - Kim, Manho

AU - Lee, Sang Kun

AU - Chu, Kon

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Objectives: Urinary tract infection (UTI) is a common medical complication experienced by patients with neurologic diseases. In this study, we established the microbial etiologies of UTI, and resistances to antibiotics in UTI as well as determining which appropriate empirical antibiotics should be used to treat UTI in neurological patients. Designs and methods: We retrospectively reviewed microbial etiologies and antimicrobial resistance among patients experiencing UTI events in the neurology ward of Seoul National University Hospital from 2007 to 2016. Results: The total number of UTI events observed was 301, and Klebsiella pneumoniae was the most common pathogen observed in UTIs. But in catheter-associated UTI (CAUTI), Enterococcus species were the most prevalent pathogens. Susceptibility to commonly-prescribed antibiotics decreased over 10 years, indicating increased antibiotic resistance in pathogens associated with UTI. ESBL-producing K. pneumoniae increased significantly, while increases of MDR K. pneumoniae, ESBL-producing E. coli, and VRE were not observed. Conclusions: The worldwide trend of increasing drug-resistant pathogens should be considered, and further studies on antibiotics resistance in UTI are needed. These data will greatly assist physicians when they select antibiotics to treat UTIs in neurological patients.

AB - Objectives: Urinary tract infection (UTI) is a common medical complication experienced by patients with neurologic diseases. In this study, we established the microbial etiologies of UTI, and resistances to antibiotics in UTI as well as determining which appropriate empirical antibiotics should be used to treat UTI in neurological patients. Designs and methods: We retrospectively reviewed microbial etiologies and antimicrobial resistance among patients experiencing UTI events in the neurology ward of Seoul National University Hospital from 2007 to 2016. Results: The total number of UTI events observed was 301, and Klebsiella pneumoniae was the most common pathogen observed in UTIs. But in catheter-associated UTI (CAUTI), Enterococcus species were the most prevalent pathogens. Susceptibility to commonly-prescribed antibiotics decreased over 10 years, indicating increased antibiotic resistance in pathogens associated with UTI. ESBL-producing K. pneumoniae increased significantly, while increases of MDR K. pneumoniae, ESBL-producing E. coli, and VRE were not observed. Conclusions: The worldwide trend of increasing drug-resistant pathogens should be considered, and further studies on antibiotics resistance in UTI are needed. These data will greatly assist physicians when they select antibiotics to treat UTIs in neurological patients.

KW - Anti-bacterial agents

KW - Bacterial

KW - Drug resistance

KW - Microbiological phenomena

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