Histotopographic distribution of placental inflammation: Analysis of 22 cases

Chong Jai Kim, Bo Hyun Yoon, Sun Hoo Park, Je G. Chi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Twenty-two placentas were investigated for the presence and patterns of inflammation by extensive examination, and divided into four groups: 1) term vaginal delivery [group I; n=6]; 2) term cesarean section delivery [group II; n=5]; 3) preterm vaginal delivery [group III; n=4], and 4) preterm cesarean section delivery [group IV; n=7]. In group I, all had deciduitis, and choriodeciduitis/ chorionitis was present in two cases (33.3%). In group II, four cases (80%) showed deciduitis and/or choriodeciduitis/chorionitis; three of these had intact membranes. In group III, three cases (75%) showed deciduitis, and two had chorionitis. In group IV, three cases (42.9%) showed no evidence of inflammation, three had deciduitis and one had deciduitis/chorioamnionitis. In all groups, membranitis was more severe, confined to the inner and mid segments in general, and deciduitis, choriodeciduitis/chorionitis and chorioamnionitis tended to overlap. The study newly demonstrates major characteristics of placental inflammation: higher prevalence and severity of inflammation in the inner segments of membrane and at the periphery of the placenta. Taking this histotopography into account, it is desirable to take sections from the placental margin, and the current concept of placental inflammation as a surrogate marker of intrauterine infection should be reevaluated.

Original languageEnglish
Pages (from-to)519-524
Number of pages6
JournalJournal of Korean Medical Science
Volume13
Issue number5
DOIs
StatePublished - Oct 1998

Fingerprint

Inflammation
Chorioamnionitis
Cesarean Section
Placenta
Membranes
Biomarkers
Infection

Keywords

  • Chorioamnionitis
  • Inflammation
  • Placenta

Cite this

Kim, Chong Jai ; Yoon, Bo Hyun ; Park, Sun Hoo ; Chi, Je G. / Histotopographic distribution of placental inflammation : Analysis of 22 cases. In: Journal of Korean Medical Science. 1998 ; Vol. 13, No. 5. pp. 519-524.
@article{9f2883552f7b453d8c72d51be6827a66,
title = "Histotopographic distribution of placental inflammation: Analysis of 22 cases",
abstract = "Twenty-two placentas were investigated for the presence and patterns of inflammation by extensive examination, and divided into four groups: 1) term vaginal delivery [group I; n=6]; 2) term cesarean section delivery [group II; n=5]; 3) preterm vaginal delivery [group III; n=4], and 4) preterm cesarean section delivery [group IV; n=7]. In group I, all had deciduitis, and choriodeciduitis/ chorionitis was present in two cases (33.3{\%}). In group II, four cases (80{\%}) showed deciduitis and/or choriodeciduitis/chorionitis; three of these had intact membranes. In group III, three cases (75{\%}) showed deciduitis, and two had chorionitis. In group IV, three cases (42.9{\%}) showed no evidence of inflammation, three had deciduitis and one had deciduitis/chorioamnionitis. In all groups, membranitis was more severe, confined to the inner and mid segments in general, and deciduitis, choriodeciduitis/chorionitis and chorioamnionitis tended to overlap. The study newly demonstrates major characteristics of placental inflammation: higher prevalence and severity of inflammation in the inner segments of membrane and at the periphery of the placenta. Taking this histotopography into account, it is desirable to take sections from the placental margin, and the current concept of placental inflammation as a surrogate marker of intrauterine infection should be reevaluated.",
keywords = "Chorioamnionitis, Inflammation, Placenta",
author = "Kim, {Chong Jai} and Yoon, {Bo Hyun} and Park, {Sun Hoo} and Chi, {Je G.}",
year = "1998",
month = "10",
doi = "10.3346/jkms.1998.13.5.519",
language = "English",
volume = "13",
pages = "519--524",
journal = "Journal of Korean medical science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "5",

}

Histotopographic distribution of placental inflammation : Analysis of 22 cases. / Kim, Chong Jai; Yoon, Bo Hyun; Park, Sun Hoo; Chi, Je G.

In: Journal of Korean Medical Science, Vol. 13, No. 5, 10.1998, p. 519-524.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Histotopographic distribution of placental inflammation

T2 - Analysis of 22 cases

AU - Kim, Chong Jai

AU - Yoon, Bo Hyun

AU - Park, Sun Hoo

AU - Chi, Je G.

PY - 1998/10

Y1 - 1998/10

N2 - Twenty-two placentas were investigated for the presence and patterns of inflammation by extensive examination, and divided into four groups: 1) term vaginal delivery [group I; n=6]; 2) term cesarean section delivery [group II; n=5]; 3) preterm vaginal delivery [group III; n=4], and 4) preterm cesarean section delivery [group IV; n=7]. In group I, all had deciduitis, and choriodeciduitis/ chorionitis was present in two cases (33.3%). In group II, four cases (80%) showed deciduitis and/or choriodeciduitis/chorionitis; three of these had intact membranes. In group III, three cases (75%) showed deciduitis, and two had chorionitis. In group IV, three cases (42.9%) showed no evidence of inflammation, three had deciduitis and one had deciduitis/chorioamnionitis. In all groups, membranitis was more severe, confined to the inner and mid segments in general, and deciduitis, choriodeciduitis/chorionitis and chorioamnionitis tended to overlap. The study newly demonstrates major characteristics of placental inflammation: higher prevalence and severity of inflammation in the inner segments of membrane and at the periphery of the placenta. Taking this histotopography into account, it is desirable to take sections from the placental margin, and the current concept of placental inflammation as a surrogate marker of intrauterine infection should be reevaluated.

AB - Twenty-two placentas were investigated for the presence and patterns of inflammation by extensive examination, and divided into four groups: 1) term vaginal delivery [group I; n=6]; 2) term cesarean section delivery [group II; n=5]; 3) preterm vaginal delivery [group III; n=4], and 4) preterm cesarean section delivery [group IV; n=7]. In group I, all had deciduitis, and choriodeciduitis/ chorionitis was present in two cases (33.3%). In group II, four cases (80%) showed deciduitis and/or choriodeciduitis/chorionitis; three of these had intact membranes. In group III, three cases (75%) showed deciduitis, and two had chorionitis. In group IV, three cases (42.9%) showed no evidence of inflammation, three had deciduitis and one had deciduitis/chorioamnionitis. In all groups, membranitis was more severe, confined to the inner and mid segments in general, and deciduitis, choriodeciduitis/chorionitis and chorioamnionitis tended to overlap. The study newly demonstrates major characteristics of placental inflammation: higher prevalence and severity of inflammation in the inner segments of membrane and at the periphery of the placenta. Taking this histotopography into account, it is desirable to take sections from the placental margin, and the current concept of placental inflammation as a surrogate marker of intrauterine infection should be reevaluated.

KW - Chorioamnionitis

KW - Inflammation

KW - Placenta

UR - http://www.scopus.com/inward/record.url?scp=0032175310&partnerID=8YFLogxK

U2 - 10.3346/jkms.1998.13.5.519

DO - 10.3346/jkms.1998.13.5.519

M3 - Article

C2 - 9811182

AN - SCOPUS:0032175310

VL - 13

SP - 519

EP - 524

JO - Journal of Korean medical science

JF - Journal of Korean medical science

SN - 1011-8934

IS - 5

ER -