GOChase: Correcting errors from Gene Ontology-based annotations for gene products

Yu Rang Park, Chan Hee Park, Ju Han Kim

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Summary: The Gene Ontology (GO) is a controlled biological vocabulary that provides three structured networks of terms to describe biological processes, cellular components and molecular functions. Many databases of gene products are annotated using the GO vocabularies. We found that some GO-updating operations are not easily traceable by the current biological databases and GO browsers. Consequently, numerous annotation errors arise and are propagated throughout biological databases and GO-based high-level analyses. GOChase is a set of web-based utilities to detect and correct the errors in GO-based annotations.

Original languageEnglish
Pages (from-to)829-831
Number of pages3
JournalBioinformatics
Volume21
Issue number6
DOIs
StatePublished - 15 Mar 2005

Bibliographical note

Funding Information:
This study was supported by a grant from Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea (0405-BC02-0604-0004).

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