Focal hyperemia in Wernicke’s encephalopathy: a preliminary arterial spin labeling MRI study

Sang Bae Ko, Tae Jung Kim, Chul Ho Sohn

Research output: Contribution to journalArticle

Abstract

Although a perturbed cerebral blood flow (CBF) has been reported in patients with Wernicke’s encephalopathy (WE), its clinical meaning is still elusive. A retrospective analysis of 10 patients (male, 6; mean age, 57.7 years) with WE between October 2012 and May 2018 was performed. Brain imaging was performed using fluid-attenuated inversion recovery (FLAIR), diffusion-weighted imaging (DWI), arterial spin labeling (ASL) perfusion-weighted imaging (PWI), and contrasted enhanced T1-weighted imaging. All patients had symmetric high signal intensity lesions in the vulnerable areas on FLAIR or DWI with focal hyperintensity on ASL-PWI (100% sensitivity). CBFlesion was variable (from 70 mL/100 g/min to 190.0 mL/100 g/min). CBFlesion/CBFwhite matter was elevated, ranging from 2.5 to 5.5. Focal hyperintensity on ASL in the vulnerable areas can be a diagnostic clue for WE.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalNeuroradiology
Volume62
Issue number1
DOIs
StatePublished - 1 Jan 2020

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Wernicke Encephalopathy
Hyperemia
Perfusion Imaging
Cerebrovascular Circulation
Neuroimaging

Keywords

  • Arterial spin labeling
  • Hyperintensity
  • Hyperperfusion
  • Perfusion-weighted imaging
  • Wernicke’s encephalopathy

Cite this

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Focal hyperemia in Wernicke’s encephalopathy : a preliminary arterial spin labeling MRI study. / Ko, Sang Bae; Kim, Tae Jung; Sohn, Chul Ho.

In: Neuroradiology, Vol. 62, No. 1, 01.01.2020, p. 105-108.

Research output: Contribution to journalArticle

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