Epstein-Barr virus-associated vesiculopapular eruption on the face of a patient with natural killer T cell lymphoma

Ji Soo Lim, Tae Min Kim, Kwang Hyun Cho

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-associated vesiculopapular eruption on the face of a patient with natural killer (NK)/T cell lymphoma. A 32-year-old Korean man presented with a late adolescent-onset recurrent necrotic papulovesicles on his face. The patient was previously diagnosed with EBV-associated NK/T cell lymphoma of the oral cavity and also had childhood-onset hypersensitivity to mosquito bites. Biopsy of his facial skin showed EBV-associated vesiculopapular eruptions, though ultraviolet provocation did not reproduce the skin lesions. EBV viral load in his peripheral blood was detected but low. The patient was treated with systemic chemotherapy. The lymphoma went into remission, but the facial EBV-associated vesiculopapular eruption had a relapsing and remitting course. Vacciniforme-like eruption, Epstein-Barr virus-associated vesiculopapular eruption, hydroa vacciniforme, natural killer T cell lymphoma.

Original languageEnglish
Pages (from-to)618-620
Number of pages3
JournalAnnals of Dermatology
Volume29
Issue number5
DOIs
StatePublished - 1 Oct 2017

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Natural Killer T-Cells
T-Cell Lymphoma
Human Herpesvirus 4
Hydroa Vacciniforme
Lymphoma
Skin
Bites and Stings
Culicidae
Viral Load
Mouth
Hypersensitivity
Leukemia
T-Lymphocytes
Biopsy
Drug Therapy

Keywords

  • Epstein-Barr virus
  • Epstein-Barr virus-associated hydroa

Cite this

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abstract = "Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-associated vesiculopapular eruption on the face of a patient with natural killer (NK)/T cell lymphoma. A 32-year-old Korean man presented with a late adolescent-onset recurrent necrotic papulovesicles on his face. The patient was previously diagnosed with EBV-associated NK/T cell lymphoma of the oral cavity and also had childhood-onset hypersensitivity to mosquito bites. Biopsy of his facial skin showed EBV-associated vesiculopapular eruptions, though ultraviolet provocation did not reproduce the skin lesions. EBV viral load in his peripheral blood was detected but low. The patient was treated with systemic chemotherapy. The lymphoma went into remission, but the facial EBV-associated vesiculopapular eruption had a relapsing and remitting course. Vacciniforme-like eruption, Epstein-Barr virus-associated vesiculopapular eruption, hydroa vacciniforme, natural killer T cell lymphoma.",
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Epstein-Barr virus-associated vesiculopapular eruption on the face of a patient with natural killer T cell lymphoma. / Lim, Ji Soo; Kim, Tae Min; Cho, Kwang Hyun.

In: Annals of Dermatology, Vol. 29, No. 5, 01.10.2017, p. 618-620.

Research output: Contribution to journalArticle

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