Endovascular Enterprise stent-assisted coil embolization for wide-necked unruptured intracranial aneurysms

Sung Kyun Hwang, Gyojun Hwang, Jae Seung Bang, Chang Wan Oh, O. Ki Kwon

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We evaluated the safety and efficacy of stent-assisted coil embolization for wide-necked unruptured intracranial aneurysms (UIA) based on the results observed in consecutive patients in a single center. This study included 116 patients (29 men, 87 women; mean age, 55.4 years) with 121 UIA which were treated by stent-assisted coil embolization from November 2008 to December 2010. A single stent type (Enterprise; Codman & Shurtleff, Raynham, MA, USA) was used. The clinical and radiological results were evaluated. Embolization was successful without complications in 94% of patients. Six patients had procedure-related thromboembolic events, resulting in neurologic symptoms in four patients, and transient angiographically-visible asymptomatic thromboembolism in two patients. Angiographic aneurysm occlusion was complete in 30.5% of patients, with a small neck remnant in 49.5%, and residual contrast filling in 19.8%. Dual antiplatelet agents were given for at least for 6 months. Thromboembolic stroke developed in three patients during follow-up; all occurred after discontinuation of clopidogrel and/or aspirin. Magnetic resonance angiography (MRA) follow-up was performed for at least 6 months. The mean follow-up was 13.4 months (range, 6-34 months). Eight patients (6.6%) demonstrated recanalization on MRA. Recoiling was performed in one patient (0.8%). The other seven patients with minor recanalization were conservatively followed. Enterprise stent-assisted coil embolization for the treatment of UIA appears to be effective and safe. Future studies including controlled prospective trials and careful follow-up are required to assess its indications and efficacy on a long term basis.

Original languageEnglish
Pages (from-to)1276-1279
Number of pages4
JournalJournal of Clinical Neuroscience
Volume20
Issue number9
DOIs
StatePublished - 1 Sep 2013

Fingerprint

Intracranial Aneurysm
Stents
Magnetic Resonance Angiography
clopidogrel
Platelet Aggregation Inhibitors
Thromboembolism
Neurologic Manifestations
Aspirin
Aneurysm
Neck
Stroke
Safety

Keywords

  • Efficacy
  • Enterprise stent
  • Safety
  • Stent-assisted coil embolization
  • Unruptured intracranial aneurysms

Cite this

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abstract = "We evaluated the safety and efficacy of stent-assisted coil embolization for wide-necked unruptured intracranial aneurysms (UIA) based on the results observed in consecutive patients in a single center. This study included 116 patients (29 men, 87 women; mean age, 55.4 years) with 121 UIA which were treated by stent-assisted coil embolization from November 2008 to December 2010. A single stent type (Enterprise; Codman & Shurtleff, Raynham, MA, USA) was used. The clinical and radiological results were evaluated. Embolization was successful without complications in 94{\%} of patients. Six patients had procedure-related thromboembolic events, resulting in neurologic symptoms in four patients, and transient angiographically-visible asymptomatic thromboembolism in two patients. Angiographic aneurysm occlusion was complete in 30.5{\%} of patients, with a small neck remnant in 49.5{\%}, and residual contrast filling in 19.8{\%}. Dual antiplatelet agents were given for at least for 6 months. Thromboembolic stroke developed in three patients during follow-up; all occurred after discontinuation of clopidogrel and/or aspirin. Magnetic resonance angiography (MRA) follow-up was performed for at least 6 months. The mean follow-up was 13.4 months (range, 6-34 months). Eight patients (6.6{\%}) demonstrated recanalization on MRA. Recoiling was performed in one patient (0.8{\%}). The other seven patients with minor recanalization were conservatively followed. Enterprise stent-assisted coil embolization for the treatment of UIA appears to be effective and safe. Future studies including controlled prospective trials and careful follow-up are required to assess its indications and efficacy on a long term basis.",
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Endovascular Enterprise stent-assisted coil embolization for wide-necked unruptured intracranial aneurysms. / Hwang, Sung Kyun; Hwang, Gyojun; Bang, Jae Seung; Oh, Chang Wan; Kwon, O. Ki.

In: Journal of Clinical Neuroscience, Vol. 20, No. 9, 01.09.2013, p. 1276-1279.

Research output: Contribution to journalArticle

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