East Asian specific asthma associated variants were discovered via exome-sequencing

Dankyu Yoon; Su Jin Baek; Kipoong Kim; Hye Ryun Kang; Jeom Kyu Lee

doi:10.1109/BIBM.2018.8621117

East Asian specific asthma associated variants were discovered via exome-sequencing

Dankyu Yoon, Su Jin Baek, Kipoong Kim, Hye Ryun Kang, Jeom Kyu Lee

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functional variants responsible for severe asthma in Korean population. We identified 10 variants of 6 candidate asthma genes (P< p>lt 10-5 comprising GPR88,AGTRAP,GTP2IRD1,KANK1,DNHD1, and DCUN1D2. Our study provides possible new therapeutic targets for asthma.

Original language	English
Title of host publication	Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018
Editors	Harald Schmidt, David Griol, Haiying Wang, Jan Baumbach, Huiru Zheng, Zoraida Callejas, Xiaohua Hu, Julie Dickerson, Le Zhang
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	2817-2819
Number of pages	3
ISBN (Electronic)	9781538654880
DOIs	https://doi.org/10.1109/BIBM.2018.8621117
State	Published - 21 Jan 2019
Event	2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 - Madrid, Spain Duration: 3 Dec 2018 → 6 Dec 2018

Publication series

Name	Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018

Conference

Conference	2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018
Country/Territory	Spain
City	Madrid
Period	3/12/18 → 6/12/18

Bibliographical note

Publisher Copyright:
© 2018 IEEE.

Keywords

Asthma
Exome-sequencing
GWAS
SNVs

Access to Document

10.1109/BIBM.2018.8621117

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Yoon, D., Baek, S. J., Kim, K., Kang, H. R., & Lee, J. K. (2019). East Asian specific asthma associated variants were discovered via exome-sequencing. In H. Schmidt, D. Griol, H. Wang, J. Baumbach, H. Zheng, Z. Callejas, X. Hu, J. Dickerson, & L. Zhang (Eds.), Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 (pp. 2817-2819). Article 8621117 (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIBM.2018.8621117

Yoon, Dankyu ; Baek, Su Jin ; Kim, Kipoong et al. / East Asian specific asthma associated variants were discovered via exome-sequencing. Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. editor / Harald Schmidt ; David Griol ; Haiying Wang ; Jan Baumbach ; Huiru Zheng ; Zoraida Callejas ; Xiaohua Hu ; Julie Dickerson ; Le Zhang. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 2817-2819 (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

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abstract = "Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functional variants responsible for severe asthma in Korean population. We identified 10 variants of 6 candidate asthma genes (P< p>lt 10-5 comprising GPR88,AGTRAP,GTP2IRD1,KANK1,DNHD1, and DCUN1D2. Our study provides possible new therapeutic targets for asthma.",

keywords = "Asthma, Exome-sequencing, GWAS, SNVs",

author = "Dankyu Yoon and Baek, {Su Jin} and Kipoong Kim and Kang, {Hye Ryun} and Lee, {Jeom Kyu}",

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doi = "10.1109/BIBM.2018.8621117",

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Yoon, D, Baek, SJ, Kim, K, Kang, HR & Lee, JK 2019, East Asian specific asthma associated variants were discovered via exome-sequencing. in H Schmidt, D Griol, H Wang, J Baumbach, H Zheng, Z Callejas, X Hu, J Dickerson & L Zhang (eds), Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018., 8621117, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018, Institute of Electrical and Electronics Engineers Inc., pp. 2817-2819, 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018, Madrid, Spain, 3/12/18. https://doi.org/10.1109/BIBM.2018.8621117

East Asian specific asthma associated variants were discovered via exome-sequencing. / Yoon, Dankyu; Baek, Su Jin; Kim, Kipoong et al.
Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. ed. / Harald Schmidt; David Griol; Haiying Wang; Jan Baumbach; Huiru Zheng; Zoraida Callejas; Xiaohua Hu; Julie Dickerson; Le Zhang. Institute of Electrical and Electronics Engineers Inc., 2019. p. 2817-2819 8621117 (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functional variants responsible for severe asthma in Korean population. We identified 10 variants of 6 candidate asthma genes (P< p>lt 10-5 comprising GPR88,AGTRAP,GTP2IRD1,KANK1,DNHD1, and DCUN1D2. Our study provides possible new therapeutic targets for asthma.

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Yoon D, Baek SJ, Kim K, Kang HR, Lee JK. East Asian specific asthma associated variants were discovered via exome-sequencing. In Schmidt H, Griol D, Wang H, Baumbach J, Zheng H, Callejas Z, Hu X, Dickerson J, Zhang L, editors, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Institute of Electrical and Electronics Engineers Inc. 2019. p. 2817-2819. 8621117. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018). doi: 10.1109/BIBM.2018.8621117

East Asian specific asthma associated variants were discovered via exome-sequencing

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Keywords

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