Dual-source, dual-energy multidetector CT for the evaluation of pancreatic tumours

A. J. Chu, Jeong Min Lee, Y. J. Lee, S. K. Moon, J. K. Han, B. I. Choi

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Objective: To investigate the potential diagnostic value of dual-energy CT (DECT) with virtual non-enhanced (VNE) and iodine-only images, and to determine the optimal mixed ratio of blended images for evaluation of pancreatic diseases. Methods: Multiphasic DECT was performed in 44 patients with focal pancreatic disease. DECT was used during the pancreatic and hepatic venous phases, and a peak kilovoltage of 120 kVp was used for both non-contrast phases. For qualitative analysis of the CT images, two radiologists assessed three image sets (VNE, iodine-only and blended images) in order to determine the acceptability of VNE in replacing true non-enhanced (TNE) images, the added value of iodine-only images and the preferred blending ratio. For quantitative analyses, the CT numbers and image noise of the pancreatic parenchyma, lesions, aorta and psoas muscle were measured. The contrast-to-noise ratio of the lesion was calculated on the pancreatic phase images. The effective radiation dose for DECT and TNE images was calculated. Statistical comparisons were made using the Friedman test, the Wilcoxon test, the paired t-test and repeated measures of analysis of variation with Bonferroni correction for multiple comparisons. Results: The level of acceptance of the VNE images in replacing TNE images was 90.9%. Regarding the iodine-only images, 50% of the cases were found to have an added value. The linear-blended images with a weighting factor of 0.5 were preferred. Conclusions: DECT was able to provide high-quality VNE images that could replace TNE images and iodine-only images showing an added value. Blended images with a weighting factor of 0.5 were preferred by the reviewers.

Original languageEnglish
JournalBritish Journal of Radiology
Volume85
Issue number1018
DOIs
StatePublished - 1 Oct 2012

Fingerprint

Iodine
Pancreatic Diseases
Neoplasms
Psoas Muscles
Aorta
Noise
Radiation
Liver

Cite this

@article{3b9c402b8d244457bcab85f870f90bc7,
title = "Dual-source, dual-energy multidetector CT for the evaluation of pancreatic tumours",
abstract = "Objective: To investigate the potential diagnostic value of dual-energy CT (DECT) with virtual non-enhanced (VNE) and iodine-only images, and to determine the optimal mixed ratio of blended images for evaluation of pancreatic diseases. Methods: Multiphasic DECT was performed in 44 patients with focal pancreatic disease. DECT was used during the pancreatic and hepatic venous phases, and a peak kilovoltage of 120 kVp was used for both non-contrast phases. For qualitative analysis of the CT images, two radiologists assessed three image sets (VNE, iodine-only and blended images) in order to determine the acceptability of VNE in replacing true non-enhanced (TNE) images, the added value of iodine-only images and the preferred blending ratio. For quantitative analyses, the CT numbers and image noise of the pancreatic parenchyma, lesions, aorta and psoas muscle were measured. The contrast-to-noise ratio of the lesion was calculated on the pancreatic phase images. The effective radiation dose for DECT and TNE images was calculated. Statistical comparisons were made using the Friedman test, the Wilcoxon test, the paired t-test and repeated measures of analysis of variation with Bonferroni correction for multiple comparisons. Results: The level of acceptance of the VNE images in replacing TNE images was 90.9{\%}. Regarding the iodine-only images, 50{\%} of the cases were found to have an added value. The linear-blended images with a weighting factor of 0.5 were preferred. Conclusions: DECT was able to provide high-quality VNE images that could replace TNE images and iodine-only images showing an added value. Blended images with a weighting factor of 0.5 were preferred by the reviewers.",
author = "Chu, {A. J.} and Lee, {Jeong Min} and Lee, {Y. J.} and Moon, {S. K.} and Han, {J. K.} and Choi, {B. I.}",
year = "2012",
month = "10",
day = "1",
doi = "10.1259/bjr/26129418",
language = "English",
volume = "85",
journal = "British Journal of Radiology",
issn = "0007-1285",
publisher = "British Institute of Radiology",
number = "1018",

}

Dual-source, dual-energy multidetector CT for the evaluation of pancreatic tumours. / Chu, A. J.; Lee, Jeong Min; Lee, Y. J.; Moon, S. K.; Han, J. K.; Choi, B. I.

In: British Journal of Radiology, Vol. 85, No. 1018, 01.10.2012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Dual-source, dual-energy multidetector CT for the evaluation of pancreatic tumours

AU - Chu, A. J.

AU - Lee, Jeong Min

AU - Lee, Y. J.

AU - Moon, S. K.

AU - Han, J. K.

AU - Choi, B. I.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - Objective: To investigate the potential diagnostic value of dual-energy CT (DECT) with virtual non-enhanced (VNE) and iodine-only images, and to determine the optimal mixed ratio of blended images for evaluation of pancreatic diseases. Methods: Multiphasic DECT was performed in 44 patients with focal pancreatic disease. DECT was used during the pancreatic and hepatic venous phases, and a peak kilovoltage of 120 kVp was used for both non-contrast phases. For qualitative analysis of the CT images, two radiologists assessed three image sets (VNE, iodine-only and blended images) in order to determine the acceptability of VNE in replacing true non-enhanced (TNE) images, the added value of iodine-only images and the preferred blending ratio. For quantitative analyses, the CT numbers and image noise of the pancreatic parenchyma, lesions, aorta and psoas muscle were measured. The contrast-to-noise ratio of the lesion was calculated on the pancreatic phase images. The effective radiation dose for DECT and TNE images was calculated. Statistical comparisons were made using the Friedman test, the Wilcoxon test, the paired t-test and repeated measures of analysis of variation with Bonferroni correction for multiple comparisons. Results: The level of acceptance of the VNE images in replacing TNE images was 90.9%. Regarding the iodine-only images, 50% of the cases were found to have an added value. The linear-blended images with a weighting factor of 0.5 were preferred. Conclusions: DECT was able to provide high-quality VNE images that could replace TNE images and iodine-only images showing an added value. Blended images with a weighting factor of 0.5 were preferred by the reviewers.

AB - Objective: To investigate the potential diagnostic value of dual-energy CT (DECT) with virtual non-enhanced (VNE) and iodine-only images, and to determine the optimal mixed ratio of blended images for evaluation of pancreatic diseases. Methods: Multiphasic DECT was performed in 44 patients with focal pancreatic disease. DECT was used during the pancreatic and hepatic venous phases, and a peak kilovoltage of 120 kVp was used for both non-contrast phases. For qualitative analysis of the CT images, two radiologists assessed three image sets (VNE, iodine-only and blended images) in order to determine the acceptability of VNE in replacing true non-enhanced (TNE) images, the added value of iodine-only images and the preferred blending ratio. For quantitative analyses, the CT numbers and image noise of the pancreatic parenchyma, lesions, aorta and psoas muscle were measured. The contrast-to-noise ratio of the lesion was calculated on the pancreatic phase images. The effective radiation dose for DECT and TNE images was calculated. Statistical comparisons were made using the Friedman test, the Wilcoxon test, the paired t-test and repeated measures of analysis of variation with Bonferroni correction for multiple comparisons. Results: The level of acceptance of the VNE images in replacing TNE images was 90.9%. Regarding the iodine-only images, 50% of the cases were found to have an added value. The linear-blended images with a weighting factor of 0.5 were preferred. Conclusions: DECT was able to provide high-quality VNE images that could replace TNE images and iodine-only images showing an added value. Blended images with a weighting factor of 0.5 were preferred by the reviewers.

UR - http://www.scopus.com/inward/record.url?scp=84866851060&partnerID=8YFLogxK

U2 - 10.1259/bjr/26129418

DO - 10.1259/bjr/26129418

M3 - Article

C2 - 22972978

AN - SCOPUS:84866851060

VL - 85

JO - British Journal of Radiology

JF - British Journal of Radiology

SN - 0007-1285

IS - 1018

ER -