Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003

Jinho Yu, Young Yoo, Do Kyun Kim, Hee Kang, Yull Koh Young

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The aim of study was to describe Mycoplasma pneumoniae epidemics in a hospital-based population. Special attention was paid to the relationship between antibody titer to M. pneumoniae and sex, age, and atopy. During the eight 6-month periods between January 2000 and December 2003, serum samples were obtained from 1,319 Korean children who presented with respiratory symptoms, and were examined for antibodies to M. pneumoniae using the indirect particle agglutination test. Geometric mean antibody titers peaked in the second half of 2000 and then decreased gradually, a second peak occurred in the second half of 2003. Likewise, the frequency of high antibody titers (≥ 1:640) also peaked during these two periods. Antibody titers in children aged 0-3 yr were lower than in older children during both peak periods and for 2 yr after the first peak. Sex and atopy had no effect on antibody titers. During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr.

Original languageEnglish
Pages (from-to)542-547
Number of pages6
JournalJournal of Korean Medical Science
Volume20
Issue number4
DOIs
StatePublished - 1 Jan 2005

Fingerprint

Mycoplasma pneumoniae
Antibodies
Agglutination Tests
Infection
Serum

Keywords

  • Age
  • Atopy
  • Child
  • Disease Outbreaks
  • Korea
  • Mycoplasma pneumoniae
  • Serologic Tests
  • Sex

Cite this

Yu, Jinho ; Yoo, Young ; Kim, Do Kyun ; Kang, Hee ; Young, Yull Koh. / Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003. In: Journal of Korean Medical Science. 2005 ; Vol. 20, No. 4. pp. 542-547.
@article{82877429208640ab947ca5f0450cd00d,
title = "Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003",
abstract = "The aim of study was to describe Mycoplasma pneumoniae epidemics in a hospital-based population. Special attention was paid to the relationship between antibody titer to M. pneumoniae and sex, age, and atopy. During the eight 6-month periods between January 2000 and December 2003, serum samples were obtained from 1,319 Korean children who presented with respiratory symptoms, and were examined for antibodies to M. pneumoniae using the indirect particle agglutination test. Geometric mean antibody titers peaked in the second half of 2000 and then decreased gradually, a second peak occurred in the second half of 2003. Likewise, the frequency of high antibody titers (≥ 1:640) also peaked during these two periods. Antibody titers in children aged 0-3 yr were lower than in older children during both peak periods and for 2 yr after the first peak. Sex and atopy had no effect on antibody titers. During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr.",
keywords = "Age, Atopy, Child, Disease Outbreaks, Korea, Mycoplasma pneumoniae, Serologic Tests, Sex",
author = "Jinho Yu and Young Yoo and Kim, {Do Kyun} and Hee Kang and Young, {Yull Koh}",
year = "2005",
month = "1",
day = "1",
doi = "10.3346/jkms.2005.20.4.542",
language = "English",
volume = "20",
pages = "542--547",
journal = "Journal of Korean medical science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "4",

}

Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003. / Yu, Jinho; Yoo, Young; Kim, Do Kyun; Kang, Hee; Young, Yull Koh.

In: Journal of Korean Medical Science, Vol. 20, No. 4, 01.01.2005, p. 542-547.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003

AU - Yu, Jinho

AU - Yoo, Young

AU - Kim, Do Kyun

AU - Kang, Hee

AU - Young, Yull Koh

PY - 2005/1/1

Y1 - 2005/1/1

N2 - The aim of study was to describe Mycoplasma pneumoniae epidemics in a hospital-based population. Special attention was paid to the relationship between antibody titer to M. pneumoniae and sex, age, and atopy. During the eight 6-month periods between January 2000 and December 2003, serum samples were obtained from 1,319 Korean children who presented with respiratory symptoms, and were examined for antibodies to M. pneumoniae using the indirect particle agglutination test. Geometric mean antibody titers peaked in the second half of 2000 and then decreased gradually, a second peak occurred in the second half of 2003. Likewise, the frequency of high antibody titers (≥ 1:640) also peaked during these two periods. Antibody titers in children aged 0-3 yr were lower than in older children during both peak periods and for 2 yr after the first peak. Sex and atopy had no effect on antibody titers. During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr.

AB - The aim of study was to describe Mycoplasma pneumoniae epidemics in a hospital-based population. Special attention was paid to the relationship between antibody titer to M. pneumoniae and sex, age, and atopy. During the eight 6-month periods between January 2000 and December 2003, serum samples were obtained from 1,319 Korean children who presented with respiratory symptoms, and were examined for antibodies to M. pneumoniae using the indirect particle agglutination test. Geometric mean antibody titers peaked in the second half of 2000 and then decreased gradually, a second peak occurred in the second half of 2003. Likewise, the frequency of high antibody titers (≥ 1:640) also peaked during these two periods. Antibody titers in children aged 0-3 yr were lower than in older children during both peak periods and for 2 yr after the first peak. Sex and atopy had no effect on antibody titers. During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr.

KW - Age

KW - Atopy

KW - Child

KW - Disease Outbreaks

KW - Korea

KW - Mycoplasma pneumoniae

KW - Serologic Tests

KW - Sex

UR - http://www.scopus.com/inward/record.url?scp=24644444853&partnerID=8YFLogxK

U2 - 10.3346/jkms.2005.20.4.542

DO - 10.3346/jkms.2005.20.4.542

M3 - Article

C2 - 16100441

AN - SCOPUS:24644444853

VL - 20

SP - 542

EP - 547

JO - Journal of Korean medical science

JF - Journal of Korean medical science

SN - 1011-8934

IS - 4

ER -