Distinct clinical characteristics of unplanned excision in synovial sarcoma

Eun Seok Choi, Ilkyu Han, Hwan-Seong Cho, Hyun Guy Kang, June Hyuk Kim, Han-Soo Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas. Methods: In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years. The clinicopathological characteristics and oncologic outcomes were compared. Results: The unplanned excision group showed longer duration of symptoms before diagnosis (p = 0.023), smaller lesion dimensions (p = 0.001), superficial location (p = 0.049), and predilection in the upper extremities (p = 0.037). Synovial sarcomas were most commonly misdiagnosed as neurogenic tumors (56%) in the upper extremities or as cystic masses (47%) in the lower extremities. Oncological outcomes, including disease-specific survival, metastasis-free survival, or local recurrence were not significantly different between the 2 groups (p = 0.159, p = 0.444, and p = 0.335, respectively). Repeated unplanned excision (p = 0.012) and delayed re-excision (p = 0.038) were significant risk factors for local recurrence in the unplanned excision group. Conclusions: Synovial sarcomas treated with unplanned excision had distinct characteristics. These findings are important for developing diagnostic and therapeutic strategies for synovial sarcoma.

Original languageEnglish
Pages (from-to)254-260
Number of pages7
JournalCiOS Clinics in Orthopedic Surgery
Volume7
Issue number2
DOIs
StatePublished - 1 Jan 2015

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Synovial Sarcoma
Upper Extremity
Recurrence
Survival
Diagnostic Errors
Lower Extremity
Extremities
Neoplasm Metastasis
Neoplasms

Keywords

  • Magnetic resonance imaging
  • Oncologic outcomes
  • Synovial sarcoma

Cite this

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title = "Distinct clinical characteristics of unplanned excision in synovial sarcoma",
abstract = "Background: We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas. Methods: In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years. The clinicopathological characteristics and oncologic outcomes were compared. Results: The unplanned excision group showed longer duration of symptoms before diagnosis (p = 0.023), smaller lesion dimensions (p = 0.001), superficial location (p = 0.049), and predilection in the upper extremities (p = 0.037). Synovial sarcomas were most commonly misdiagnosed as neurogenic tumors (56{\%}) in the upper extremities or as cystic masses (47{\%}) in the lower extremities. Oncological outcomes, including disease-specific survival, metastasis-free survival, or local recurrence were not significantly different between the 2 groups (p = 0.159, p = 0.444, and p = 0.335, respectively). Repeated unplanned excision (p = 0.012) and delayed re-excision (p = 0.038) were significant risk factors for local recurrence in the unplanned excision group. Conclusions: Synovial sarcomas treated with unplanned excision had distinct characteristics. These findings are important for developing diagnostic and therapeutic strategies for synovial sarcoma.",
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Distinct clinical characteristics of unplanned excision in synovial sarcoma. / Choi, Eun Seok; Han, Ilkyu; Cho, Hwan-Seong; Kang, Hyun Guy; Kim, June Hyuk; Kim, Han-Soo.

In: CiOS Clinics in Orthopedic Surgery, Vol. 7, No. 2, 01.01.2015, p. 254-260.

Research output: Contribution to journalArticle

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T1 - Distinct clinical characteristics of unplanned excision in synovial sarcoma

AU - Choi, Eun Seok

AU - Han, Ilkyu

AU - Cho, Hwan-Seong

AU - Kang, Hyun Guy

AU - Kim, June Hyuk

AU - Kim, Han-Soo

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