Differential kinematic features of the hyoid bone during swallowing in patients with Parkinson's disease

Woo Hyung Lee, Min Hyuk Lim, Hyung Seok Nam, Yoon Jae Kim, Han Gil Seo, Moon Suk Bang, Min Yong Seong, Byung-Mo Oh, Sungwan Kim

Research output: Contribution to journalArticleResearchpeer-review

Abstract

This study aimed to investigate spatiotemporal characteristics of the hyoid bone during swallowing in patients with Parkinson's disease (PD) and dysphagia. Spatiotemporal data of the hyoid bone was obtained from videofluoroscopic images of 69 subjects (23 patients with PD, 23 age- and sex-matched healthy elderly controls, and 23 healthy young controls). Normalized profiles of displacement/velocity were analyzed during different periods (percentile) of swallowing using functional regression analysis, and the maximal values were compared between the groups. Maximal horizontal displacement and velocity were significantly decreased during the initial backward (P = 0.006 and P < 0.001, respectively) and forward (P = 0.008 and P < 0.001, respectively) motions in PD patients compared to elderly controls. Maximal vertical velocity was significantly lower in PD patients than in elderly controls (P = 0.001). No significant difference was observed in maximal displacement and velocity in both horizontal and vertical planes between the healthy elderly and young controls, although horizontal displacement was significantly decreased during the forward motion (51st–57th percentiles) in the elderly controls. In conclusion, reduced horizontal displacement and velocity of the hyoid bone during the forward motion would be due to combined effects of disease and aging, whereas those over the initial backward motion may be considered specific to patients with PD.

Original languageEnglish
Pages (from-to)57-64
Number of pages8
JournalJournal of Electromyography and Kinesiology
Volume47
DOIs
StatePublished - 1 Aug 2019

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Hyoid Bone
Deglutition
Biomechanical Phenomena
Parkinson Disease
Deglutition Disorders
Regression Analysis

Keywords

  • Deglutition
  • Functional data
  • Hyoid bone
  • Motion analysis
  • Parkinson's disease

Cite this

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title = "Differential kinematic features of the hyoid bone during swallowing in patients with Parkinson's disease",
abstract = "This study aimed to investigate spatiotemporal characteristics of the hyoid bone during swallowing in patients with Parkinson's disease (PD) and dysphagia. Spatiotemporal data of the hyoid bone was obtained from videofluoroscopic images of 69 subjects (23 patients with PD, 23 age- and sex-matched healthy elderly controls, and 23 healthy young controls). Normalized profiles of displacement/velocity were analyzed during different periods (percentile) of swallowing using functional regression analysis, and the maximal values were compared between the groups. Maximal horizontal displacement and velocity were significantly decreased during the initial backward (P = 0.006 and P < 0.001, respectively) and forward (P = 0.008 and P < 0.001, respectively) motions in PD patients compared to elderly controls. Maximal vertical velocity was significantly lower in PD patients than in elderly controls (P = 0.001). No significant difference was observed in maximal displacement and velocity in both horizontal and vertical planes between the healthy elderly and young controls, although horizontal displacement was significantly decreased during the forward motion (51st–57th percentiles) in the elderly controls. In conclusion, reduced horizontal displacement and velocity of the hyoid bone during the forward motion would be due to combined effects of disease and aging, whereas those over the initial backward motion may be considered specific to patients with PD.",
keywords = "Deglutition, Functional data, Hyoid bone, Motion analysis, Parkinson's disease",
author = "Lee, {Woo Hyung} and Lim, {Min Hyuk} and Nam, {Hyung Seok} and Kim, {Yoon Jae} and Seo, {Han Gil} and Bang, {Moon Suk} and Seong, {Min Yong} and Byung-Mo Oh and Sungwan Kim",
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Differential kinematic features of the hyoid bone during swallowing in patients with Parkinson's disease. / Lee, Woo Hyung; Lim, Min Hyuk; Nam, Hyung Seok; Kim, Yoon Jae; Seo, Han Gil; Bang, Moon Suk; Seong, Min Yong; Oh, Byung-Mo; Kim, Sungwan.

In: Journal of Electromyography and Kinesiology, Vol. 47, 01.08.2019, p. 57-64.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Differential kinematic features of the hyoid bone during swallowing in patients with Parkinson's disease

AU - Lee, Woo Hyung

AU - Lim, Min Hyuk

AU - Nam, Hyung Seok

AU - Kim, Yoon Jae

AU - Seo, Han Gil

AU - Bang, Moon Suk

AU - Seong, Min Yong

AU - Oh, Byung-Mo

AU - Kim, Sungwan

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N2 - This study aimed to investigate spatiotemporal characteristics of the hyoid bone during swallowing in patients with Parkinson's disease (PD) and dysphagia. Spatiotemporal data of the hyoid bone was obtained from videofluoroscopic images of 69 subjects (23 patients with PD, 23 age- and sex-matched healthy elderly controls, and 23 healthy young controls). Normalized profiles of displacement/velocity were analyzed during different periods (percentile) of swallowing using functional regression analysis, and the maximal values were compared between the groups. Maximal horizontal displacement and velocity were significantly decreased during the initial backward (P = 0.006 and P < 0.001, respectively) and forward (P = 0.008 and P < 0.001, respectively) motions in PD patients compared to elderly controls. Maximal vertical velocity was significantly lower in PD patients than in elderly controls (P = 0.001). No significant difference was observed in maximal displacement and velocity in both horizontal and vertical planes between the healthy elderly and young controls, although horizontal displacement was significantly decreased during the forward motion (51st–57th percentiles) in the elderly controls. In conclusion, reduced horizontal displacement and velocity of the hyoid bone during the forward motion would be due to combined effects of disease and aging, whereas those over the initial backward motion may be considered specific to patients with PD.

AB - This study aimed to investigate spatiotemporal characteristics of the hyoid bone during swallowing in patients with Parkinson's disease (PD) and dysphagia. Spatiotemporal data of the hyoid bone was obtained from videofluoroscopic images of 69 subjects (23 patients with PD, 23 age- and sex-matched healthy elderly controls, and 23 healthy young controls). Normalized profiles of displacement/velocity were analyzed during different periods (percentile) of swallowing using functional regression analysis, and the maximal values were compared between the groups. Maximal horizontal displacement and velocity were significantly decreased during the initial backward (P = 0.006 and P < 0.001, respectively) and forward (P = 0.008 and P < 0.001, respectively) motions in PD patients compared to elderly controls. Maximal vertical velocity was significantly lower in PD patients than in elderly controls (P = 0.001). No significant difference was observed in maximal displacement and velocity in both horizontal and vertical planes between the healthy elderly and young controls, although horizontal displacement was significantly decreased during the forward motion (51st–57th percentiles) in the elderly controls. In conclusion, reduced horizontal displacement and velocity of the hyoid bone during the forward motion would be due to combined effects of disease and aging, whereas those over the initial backward motion may be considered specific to patients with PD.

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