Diagnostic performance of virtual gastroscopy using MDCT in early gastric cancer compared with 2D axial CT: Focusing on interobserver variation

Jung Hoon Kim, Won Eun Hyo, Ho Choi Jae, Sook Hong Seong, Weechang Kang, Ho Auh Yong

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

OBJECTIVE. The objective of our study was to assess the diagnostic performance of virtual gastroscopy using MDCT for the detection of early gastric cancer (EGC) compared with 2D axial CT, focusing on interobserver reliability. MATERIALS AND METHODS. During an 11-month period, we performed CT examinations of 94 consecutive patients with EGC and a control group composed of 68 patients without EGC. Three radiologists retrospectively interpreted the 2D axial CT and virtual gastroscopy images. Diagnostic performances were compared within each observer using the area under the receiver operating characteristic curve (A.). Sensitivity and specificity were also calculated for each individual observer. The simple kappa statistic was used to evaluate interobserver reliability in the detection of EGC. RESULTS. The diagnostic performance for overall lesion detection in patients with EGC was significantly higher with virtual gastroscopy (Az = 0.829-0.885) than with 2D axial CT (Az = 0.734-0.793) (p < 0.001). The sensitivity and specificity of virtual gastroscopy for EGC were 78.7-84.0% and 83.8-91.2%, respectively. The sensitivity and specificity of 2D axial CT for EGC were 62.8-69.2% and 83.8-92.7%, respectively. Virtual gastroscopy showed a higher sensitivity for EGC than 2D axial CT (p < 0.001). The interobserver reliabilities showed moderate to substantial agreement (κ = 0.40-0.74 for 2D axial CT, κ = 0.57-0.71 for virtual gastroscopy). CONCLUSION. Virtual gastroscopy showed excellent results with a good interobserver reliability for the detection of EGC compared with 2D axial CT.

Original languageEnglish
Pages (from-to)299-305
Number of pages7
JournalAmerican Journal of Roentgenology
Volume189
Issue number2
DOIs
StatePublished - 1 Aug 2007

Fingerprint

Gastroscopy
Observer Variation
Stomach Neoplasms
Sensitivity and Specificity
ROC Curve
Control Groups

Keywords

  • 2D CT
  • Gastric cancer
  • MDCT
  • Oncologic imaging
  • Virtual gastroscopy

Cite this

Kim, Jung Hoon ; Hyo, Won Eun ; Jae, Ho Choi ; Seong, Sook Hong ; Kang, Weechang ; Yong, Ho Auh. / Diagnostic performance of virtual gastroscopy using MDCT in early gastric cancer compared with 2D axial CT : Focusing on interobserver variation. In: American Journal of Roentgenology. 2007 ; Vol. 189, No. 2. pp. 299-305.
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abstract = "OBJECTIVE. The objective of our study was to assess the diagnostic performance of virtual gastroscopy using MDCT for the detection of early gastric cancer (EGC) compared with 2D axial CT, focusing on interobserver reliability. MATERIALS AND METHODS. During an 11-month period, we performed CT examinations of 94 consecutive patients with EGC and a control group composed of 68 patients without EGC. Three radiologists retrospectively interpreted the 2D axial CT and virtual gastroscopy images. Diagnostic performances were compared within each observer using the area under the receiver operating characteristic curve (A.). Sensitivity and specificity were also calculated for each individual observer. The simple kappa statistic was used to evaluate interobserver reliability in the detection of EGC. RESULTS. The diagnostic performance for overall lesion detection in patients with EGC was significantly higher with virtual gastroscopy (Az = 0.829-0.885) than with 2D axial CT (Az = 0.734-0.793) (p < 0.001). The sensitivity and specificity of virtual gastroscopy for EGC were 78.7-84.0{\%} and 83.8-91.2{\%}, respectively. The sensitivity and specificity of 2D axial CT for EGC were 62.8-69.2{\%} and 83.8-92.7{\%}, respectively. Virtual gastroscopy showed a higher sensitivity for EGC than 2D axial CT (p < 0.001). The interobserver reliabilities showed moderate to substantial agreement (κ = 0.40-0.74 for 2D axial CT, κ = 0.57-0.71 for virtual gastroscopy). CONCLUSION. Virtual gastroscopy showed excellent results with a good interobserver reliability for the detection of EGC compared with 2D axial CT.",
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Diagnostic performance of virtual gastroscopy using MDCT in early gastric cancer compared with 2D axial CT : Focusing on interobserver variation. / Kim, Jung Hoon; Hyo, Won Eun; Jae, Ho Choi; Seong, Sook Hong; Kang, Weechang; Yong, Ho Auh.

In: American Journal of Roentgenology, Vol. 189, No. 2, 01.08.2007, p. 299-305.

Research output: Contribution to journalArticle

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AU - Kim, Jung Hoon

AU - Hyo, Won Eun

AU - Jae, Ho Choi

AU - Seong, Sook Hong

AU - Kang, Weechang

AU - Yong, Ho Auh

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N2 - OBJECTIVE. The objective of our study was to assess the diagnostic performance of virtual gastroscopy using MDCT for the detection of early gastric cancer (EGC) compared with 2D axial CT, focusing on interobserver reliability. MATERIALS AND METHODS. During an 11-month period, we performed CT examinations of 94 consecutive patients with EGC and a control group composed of 68 patients without EGC. Three radiologists retrospectively interpreted the 2D axial CT and virtual gastroscopy images. Diagnostic performances were compared within each observer using the area under the receiver operating characteristic curve (A.). Sensitivity and specificity were also calculated for each individual observer. The simple kappa statistic was used to evaluate interobserver reliability in the detection of EGC. RESULTS. The diagnostic performance for overall lesion detection in patients with EGC was significantly higher with virtual gastroscopy (Az = 0.829-0.885) than with 2D axial CT (Az = 0.734-0.793) (p < 0.001). The sensitivity and specificity of virtual gastroscopy for EGC were 78.7-84.0% and 83.8-91.2%, respectively. The sensitivity and specificity of 2D axial CT for EGC were 62.8-69.2% and 83.8-92.7%, respectively. Virtual gastroscopy showed a higher sensitivity for EGC than 2D axial CT (p < 0.001). The interobserver reliabilities showed moderate to substantial agreement (κ = 0.40-0.74 for 2D axial CT, κ = 0.57-0.71 for virtual gastroscopy). CONCLUSION. Virtual gastroscopy showed excellent results with a good interobserver reliability for the detection of EGC compared with 2D axial CT.

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KW - Oncologic imaging

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