Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation

Eunbi Ye, Seung Hyun Lee, Jinhwan Baik, Seon Young Ryu, Won Hoon Song, Eue-Keun Choi, Chang Wook Jeong, Sung Min Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Abstract

The sympathetic nervous system was known to play an important role in resistant hypertension. Surgical sympathectomy for renal sympathetic nerve removal were performed since the 1930s. Although effective, it had many serious side effects and complications due to non-selective property. Recently, catheter based RDN system using radiofrequency (RF) ablation was developed and considered promising, however, it failed in sham controlled trial. Therefore, there are needs for safe and effective RDN strategies considering the anatomical structure of the renal arteries and sympathetic nerves. In this paper, we propose a novel surgical instruments for laparoscopic renal denervation (RDN) to treat of resistant hypertension through a 3D realistic model using nephrectomy tissues. Laparoscopic RDN is a new surgical approach to remove renal sympathetic nerves.

Original languageEnglish
Title of host publication40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4524-4527
Number of pages4
ISBN (Electronic)9781538636466
DOIs
StatePublished - 26 Oct 2018
Event40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
Duration: 18 Jul 201821 Jul 2018

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2018-July
ISSN (Print)1557-170X

Other

Other40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
CountryUnited States
CityHonolulu
Period18/07/1821/07/18

Fingerprint

Catheters
Neurology
Denervation
Ablation
Tissue
Kidney
Hypertension
Sympathectomy
Sympathetic Nervous System
Renal Artery
Nephrectomy
Surgical Instruments

Cite this

Ye, E., Lee, S. H., Baik, J., Ryu, S. Y., Song, W. H., Choi, E-K., ... Park, S. M. (2018). Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 (pp. 4524-4527). [8513120] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2018.8513120
Ye, Eunbi ; Lee, Seung Hyun ; Baik, Jinhwan ; Ryu, Seon Young ; Song, Won Hoon ; Choi, Eue-Keun ; Jeong, Chang Wook ; Park, Sung Min. / Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 4524-4527 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
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abstract = "The sympathetic nervous system was known to play an important role in resistant hypertension. Surgical sympathectomy for renal sympathetic nerve removal were performed since the 1930s. Although effective, it had many serious side effects and complications due to non-selective property. Recently, catheter based RDN system using radiofrequency (RF) ablation was developed and considered promising, however, it failed in sham controlled trial. Therefore, there are needs for safe and effective RDN strategies considering the anatomical structure of the renal arteries and sympathetic nerves. In this paper, we propose a novel surgical instruments for laparoscopic renal denervation (RDN) to treat of resistant hypertension through a 3D realistic model using nephrectomy tissues. Laparoscopic RDN is a new surgical approach to remove renal sympathetic nerves.",
author = "Eunbi Ye and Lee, {Seung Hyun} and Jinhwan Baik and Ryu, {Seon Young} and Song, {Won Hoon} and Eue-Keun Choi and Jeong, {Chang Wook} and Park, {Sung Min}",
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Ye, E, Lee, SH, Baik, J, Ryu, SY, Song, WH, Choi, E-K, Jeong, CW & Park, SM 2018, Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation. in 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018., 8513120, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2018-July, Institute of Electrical and Electronics Engineers Inc., pp. 4524-4527, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018, Honolulu, United States, 18/07/18. https://doi.org/10.1109/EMBC.2018.8513120

Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation. / Ye, Eunbi; Lee, Seung Hyun; Baik, Jinhwan; Ryu, Seon Young; Song, Won Hoon; Choi, Eue-Keun; Jeong, Chang Wook; Park, Sung Min.

40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 4524-4527 8513120 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

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AB - The sympathetic nervous system was known to play an important role in resistant hypertension. Surgical sympathectomy for renal sympathetic nerve removal were performed since the 1930s. Although effective, it had many serious side effects and complications due to non-selective property. Recently, catheter based RDN system using radiofrequency (RF) ablation was developed and considered promising, however, it failed in sham controlled trial. Therefore, there are needs for safe and effective RDN strategies considering the anatomical structure of the renal arteries and sympathetic nerves. In this paper, we propose a novel surgical instruments for laparoscopic renal denervation (RDN) to treat of resistant hypertension through a 3D realistic model using nephrectomy tissues. Laparoscopic RDN is a new surgical approach to remove renal sympathetic nerves.

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Ye E, Lee SH, Baik J, Ryu SY, Song WH, Choi E-K et al. Developing a Computational Model of Renal Nerves and Surgical System for Laparoscopic Renal Denervation. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 4524-4527. 8513120. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2018.8513120