Design modifications of high-flexion TKA do not improve short term clinical and radiographic outcomes

Jai Gon Seo, Young Wan Moon, Moon Jong Chang, Byung Chul Jo, Yong Beom Park, Deuk Soo Lim, Byung Hoon Lee

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Background: The prosthesis of contemporary total knee arthroplasty (TKA) has been modified to provide a more familiar environment for higher flexion angle of the replaced knee. The design modifications continue based on evidence reported in the literature. However, whether these modifications of the prosthesis design lead to improvements in clinical results needs further investigation. We determined whether the prosthesis modifications based on recent evidence improve clinical and radiographic results following high flexion TKA. Methods: 524 patients who underwent primary TKA using two different high flexion prostheses were divided to Group 1 (HF-1) using a high flexion prosthesis, group 2 (HF-2) using the more recently devised high flexion prosthesis, which claims to be adopted from evidence proposed in the literature. Clinical outcomes included ranges of motion (ROM), the Knee Society knee and function score (KSKS and KSFS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC) score, radiologic evaluation, and complication related to surgery. Results: No differences in terms of clinical and radiographic results were observed between the groups at the 2 year follow-up. The mean ROM was 123°and 124° in the HF-1 and HF-2 groups, respectively. KSKS were 90 and 89.1, KSFS were 76.6 and 81.8, and total WOMAC scores were 23.1 and 24.9 in the HF-1 and HF- 2 groups. No differences of the incidences of radiolucency on radiographs (1.4% in HF-1, 2.1% in HF-2) and dislocation (1 case in HF-1 only) was observed. Conclusions: Even if recent modifications in the design of high flexion TKA prosthesis were based on evidence in the literature, they did not provide meaningful improvements in short-term clinical and radiographic outcomes after TKA. Surgeons should consider our findings when choosing a prosthesis for their patients.

Original languageEnglish
Article number433
JournalBMC musculoskeletal disorders
Issue number1
StatePublished - 2014


  • High-flexion knee
  • Outcome scores
  • Range of motion
  • Total knee arthroplasty

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