Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease

Moritz H. Albrecht, Akos Varga-Szemes, U. Joseph Schoepf, Georg Apfaltrer, Jiaqian Xu, Kwang Nam Jin, Anthony M. Hlavacek, Shahryar M. Chowdhury, Pal Suranyi, Christian Tesche, Carlo N. De Cecco, Davide Piccini, Matthias Stuber, Giulia Ginami, Thomas J. Vogl, Arni Nutting

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives: To evaluate a self-navigated free-breathing three-dimensional (SNFB3D) radial whole-heart MRA technique for assessment of main coronary arteries (CAs) and side branches in patients with congenital heart disease (CHD). Methods: SNFB3D-MRA datasets of 109 patients (20.1±11.8 years) were included. Three readers assessed the depiction of CA segments, diagnostic confidence in determining CA dominance, overall image quality and the ability to freeze cardiac and respiratory motion. Vessel sharpness was quantitatively measured. Results: The percentages of cases with excellent CA depiction were as follows (mean score): left main, 92.6 % (1.92); left anterior descending (LAD), 88.3 % (1.88); right (RCA), 87.8 % (1.85); left circumflex, 82.8 % (1.82); posterior descending, 50.2 % (1.50) and first diagonal, 39.8 % (1.39). High diagnostic confidence for the assessment of CA dominance was achieved in 56.2 % of MRA examinations (mean score, 1.56). Cardiac motion freezing (mean score, 2.18; Pearson’s r=0.73, P<0.029) affected image quality more than respiratory motion freezing (mean score, 2.20; r=0.58, P<0.029). Mean quantitative vessel sharpness of the internal thoracic artery, RCA and LAD were 53.1, 52.5 and 48.7 %, respectively. Conclusions: Most SNFB3D-MRA examinations allow for excellent depiction of the main CAs in young CHD patients; visualisation of side branches remains limited. Key Points: • Self-navigated free-breathing three-dimensional magnetic resonance angiography (SNFB3D-MRA) sufficiently visualises coronary arteries (CAs). • Depiction of main CAs in patients with congenital heart disease is excellent. • Visualisation of CA side branches using SNFB3D-MRA is limited. • SNFB3D-MRA image quality is especially correlated to cardiac motion freezing ability.

Original languageEnglish
Pages (from-to)1267-1275
Number of pages9
JournalEuropean Radiology
Volume28
Issue number3
DOIs
StatePublished - 1 Mar 2018

Fingerprint

Magnetic Resonance Angiography
Heart Diseases
Coronary Vessels
Respiration
Freezing
Mammary Arteries

Keywords

  • Cardiac imaging
  • Congenital heart disease
  • Coronary angiography
  • Magnetic resonance angiography
  • Paediatric radiology

Cite this

Albrecht, Moritz H. ; Varga-Szemes, Akos ; Schoepf, U. Joseph ; Apfaltrer, Georg ; Xu, Jiaqian ; Jin, Kwang Nam ; Hlavacek, Anthony M. ; Chowdhury, Shahryar M. ; Suranyi, Pal ; Tesche, Christian ; De Cecco, Carlo N. ; Piccini, Davide ; Stuber, Matthias ; Ginami, Giulia ; Vogl, Thomas J. ; Nutting, Arni. / Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease. In: European Radiology. 2018 ; Vol. 28, No. 3. pp. 1267-1275.
@article{fb167667a0184aacaf5277fc07b6e72d,
title = "Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease",
abstract = "Objectives: To evaluate a self-navigated free-breathing three-dimensional (SNFB3D) radial whole-heart MRA technique for assessment of main coronary arteries (CAs) and side branches in patients with congenital heart disease (CHD). Methods: SNFB3D-MRA datasets of 109 patients (20.1±11.8 years) were included. Three readers assessed the depiction of CA segments, diagnostic confidence in determining CA dominance, overall image quality and the ability to freeze cardiac and respiratory motion. Vessel sharpness was quantitatively measured. Results: The percentages of cases with excellent CA depiction were as follows (mean score): left main, 92.6 {\%} (1.92); left anterior descending (LAD), 88.3 {\%} (1.88); right (RCA), 87.8 {\%} (1.85); left circumflex, 82.8 {\%} (1.82); posterior descending, 50.2 {\%} (1.50) and first diagonal, 39.8 {\%} (1.39). High diagnostic confidence for the assessment of CA dominance was achieved in 56.2 {\%} of MRA examinations (mean score, 1.56). Cardiac motion freezing (mean score, 2.18; Pearson’s r=0.73, P<0.029) affected image quality more than respiratory motion freezing (mean score, 2.20; r=0.58, P<0.029). Mean quantitative vessel sharpness of the internal thoracic artery, RCA and LAD were 53.1, 52.5 and 48.7 {\%}, respectively. Conclusions: Most SNFB3D-MRA examinations allow for excellent depiction of the main CAs in young CHD patients; visualisation of side branches remains limited. Key Points: • Self-navigated free-breathing three-dimensional magnetic resonance angiography (SNFB3D-MRA) sufficiently visualises coronary arteries (CAs). • Depiction of main CAs in patients with congenital heart disease is excellent. • Visualisation of CA side branches using SNFB3D-MRA is limited. • SNFB3D-MRA image quality is especially correlated to cardiac motion freezing ability.",
keywords = "Cardiac imaging, Congenital heart disease, Coronary angiography, Magnetic resonance angiography, Paediatric radiology",
author = "Albrecht, {Moritz H.} and Akos Varga-Szemes and Schoepf, {U. Joseph} and Georg Apfaltrer and Jiaqian Xu and Jin, {Kwang Nam} and Hlavacek, {Anthony M.} and Chowdhury, {Shahryar M.} and Pal Suranyi and Christian Tesche and {De Cecco}, {Carlo N.} and Davide Piccini and Matthias Stuber and Giulia Ginami and Vogl, {Thomas J.} and Arni Nutting",
year = "2018",
month = "3",
day = "1",
doi = "10.1007/s00330-017-5035-1",
language = "English",
volume = "28",
pages = "1267--1275",
journal = "European radiology",
issn = "0938-7994",
publisher = "Springer Verlag",
number = "3",

}

Albrecht, MH, Varga-Szemes, A, Schoepf, UJ, Apfaltrer, G, Xu, J, Jin, KN, Hlavacek, AM, Chowdhury, SM, Suranyi, P, Tesche, C, De Cecco, CN, Piccini, D, Stuber, M, Ginami, G, Vogl, TJ & Nutting, A 2018, 'Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease', European Radiology, vol. 28, no. 3, pp. 1267-1275. https://doi.org/10.1007/s00330-017-5035-1

Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease. / Albrecht, Moritz H.; Varga-Szemes, Akos; Schoepf, U. Joseph; Apfaltrer, Georg; Xu, Jiaqian; Jin, Kwang Nam; Hlavacek, Anthony M.; Chowdhury, Shahryar M.; Suranyi, Pal; Tesche, Christian; De Cecco, Carlo N.; Piccini, Davide; Stuber, Matthias; Ginami, Giulia; Vogl, Thomas J.; Nutting, Arni.

In: European Radiology, Vol. 28, No. 3, 01.03.2018, p. 1267-1275.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Coronary artery assessment using self-navigated free-breathing radial whole-heart magnetic resonance angiography in patients with congenital heart disease

AU - Albrecht, Moritz H.

AU - Varga-Szemes, Akos

AU - Schoepf, U. Joseph

AU - Apfaltrer, Georg

AU - Xu, Jiaqian

AU - Jin, Kwang Nam

AU - Hlavacek, Anthony M.

AU - Chowdhury, Shahryar M.

AU - Suranyi, Pal

AU - Tesche, Christian

AU - De Cecco, Carlo N.

AU - Piccini, Davide

AU - Stuber, Matthias

AU - Ginami, Giulia

AU - Vogl, Thomas J.

AU - Nutting, Arni

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Objectives: To evaluate a self-navigated free-breathing three-dimensional (SNFB3D) radial whole-heart MRA technique for assessment of main coronary arteries (CAs) and side branches in patients with congenital heart disease (CHD). Methods: SNFB3D-MRA datasets of 109 patients (20.1±11.8 years) were included. Three readers assessed the depiction of CA segments, diagnostic confidence in determining CA dominance, overall image quality and the ability to freeze cardiac and respiratory motion. Vessel sharpness was quantitatively measured. Results: The percentages of cases with excellent CA depiction were as follows (mean score): left main, 92.6 % (1.92); left anterior descending (LAD), 88.3 % (1.88); right (RCA), 87.8 % (1.85); left circumflex, 82.8 % (1.82); posterior descending, 50.2 % (1.50) and first diagonal, 39.8 % (1.39). High diagnostic confidence for the assessment of CA dominance was achieved in 56.2 % of MRA examinations (mean score, 1.56). Cardiac motion freezing (mean score, 2.18; Pearson’s r=0.73, P<0.029) affected image quality more than respiratory motion freezing (mean score, 2.20; r=0.58, P<0.029). Mean quantitative vessel sharpness of the internal thoracic artery, RCA and LAD were 53.1, 52.5 and 48.7 %, respectively. Conclusions: Most SNFB3D-MRA examinations allow for excellent depiction of the main CAs in young CHD patients; visualisation of side branches remains limited. Key Points: • Self-navigated free-breathing three-dimensional magnetic resonance angiography (SNFB3D-MRA) sufficiently visualises coronary arteries (CAs). • Depiction of main CAs in patients with congenital heart disease is excellent. • Visualisation of CA side branches using SNFB3D-MRA is limited. • SNFB3D-MRA image quality is especially correlated to cardiac motion freezing ability.

AB - Objectives: To evaluate a self-navigated free-breathing three-dimensional (SNFB3D) radial whole-heart MRA technique for assessment of main coronary arteries (CAs) and side branches in patients with congenital heart disease (CHD). Methods: SNFB3D-MRA datasets of 109 patients (20.1±11.8 years) were included. Three readers assessed the depiction of CA segments, diagnostic confidence in determining CA dominance, overall image quality and the ability to freeze cardiac and respiratory motion. Vessel sharpness was quantitatively measured. Results: The percentages of cases with excellent CA depiction were as follows (mean score): left main, 92.6 % (1.92); left anterior descending (LAD), 88.3 % (1.88); right (RCA), 87.8 % (1.85); left circumflex, 82.8 % (1.82); posterior descending, 50.2 % (1.50) and first diagonal, 39.8 % (1.39). High diagnostic confidence for the assessment of CA dominance was achieved in 56.2 % of MRA examinations (mean score, 1.56). Cardiac motion freezing (mean score, 2.18; Pearson’s r=0.73, P<0.029) affected image quality more than respiratory motion freezing (mean score, 2.20; r=0.58, P<0.029). Mean quantitative vessel sharpness of the internal thoracic artery, RCA and LAD were 53.1, 52.5 and 48.7 %, respectively. Conclusions: Most SNFB3D-MRA examinations allow for excellent depiction of the main CAs in young CHD patients; visualisation of side branches remains limited. Key Points: • Self-navigated free-breathing three-dimensional magnetic resonance angiography (SNFB3D-MRA) sufficiently visualises coronary arteries (CAs). • Depiction of main CAs in patients with congenital heart disease is excellent. • Visualisation of CA side branches using SNFB3D-MRA is limited. • SNFB3D-MRA image quality is especially correlated to cardiac motion freezing ability.

KW - Cardiac imaging

KW - Congenital heart disease

KW - Coronary angiography

KW - Magnetic resonance angiography

KW - Paediatric radiology

UR - http://www.scopus.com/inward/record.url?scp=85029000571&partnerID=8YFLogxK

U2 - 10.1007/s00330-017-5035-1

DO - 10.1007/s00330-017-5035-1

M3 - Article

C2 - 28887662

AN - SCOPUS:85029000571

VL - 28

SP - 1267

EP - 1275

JO - European radiology

JF - European radiology

SN - 0938-7994

IS - 3

ER -