Comparison of the efficacy of low anterior resection with primary anastomosis and Hartmann's procedure in advanced primary or recurrent epithelial ovarian cancer

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Abstract

Objective: We compared the efficacy between low anterior resection with primary anastomosis (LARA) and Hartmann's procedure (HP) in advanced primary or recurrent epithelial ovarian cancer (EOC). Study design: We reviewed medical records of 61 patients with advanced primary or recurrent EOC who underwent LARA or HP between January 1998 and August 2008. In 37 patients with primary FIGO stage III-IV EOC, 22 and 15 received LARA and HP, whereas 10 and 14 underwent LARA and HP in 24 patients with recurrent EOC. Results: Postoperative complications (recto-vaginal fistula, leakage at the anastomotic site, postoperative ileus for ≥7 days, wound dehiscence, angina pectoris, acute renal failure, febrile illness, reoperation within 30 days and postoperative death), surgical outcomes (time of operation, estimated blood loss, transfusion, postoperative hospitalization and time to normal diet) were not different between LARA and HP. Progression-free survival (median, 20 vs. 17 months) and overall survivals (median, 70 vs. 36 months) in advanced primary EOC, and surgery-specific survival (median, 32 vs. 17 months) and overall survivals (median, 52 vs. 61 months) in recurrent EOC were also not different between LARA and HP (p > 0.05). Moreover, the recto-sigmoid obstruction after LARA was developed in 9.1% in advanced primary EOC and 10% in recurrent EOC, and the stoma-free rates were high in LARA (90.9% in advanced primary EOC; 90% in recurrent EOC). Conclusions: LARA may be an optimal procedure for bowel surgery without differences in postoperative complication, surgical outcomes and survival when compared with Hartmann's procedure in advanced primary or recurrent EOC. Furthermore, the high stoma-free rate after LARA can improve postoperative quality of life by avoiding the permanent stoma formation.

Original languageEnglish
Pages (from-to)194-198
Number of pages5
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume156
Issue number2
DOIs
StatePublished - Jun 2011

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Survival
Ovarian epithelial cancer
Vaginal Fistula
Anastomotic Leak
Ileus
Angina Pectoris
Sigmoid Colon
Reoperation
Acute Kidney Injury
Blood Transfusion
Disease-Free Survival
Medical Records
Hospitalization
Fever
Quality of Life
Diet
Wounds and Injuries

Keywords

  • Epithelial ovarian cancer
  • Hartmann's procedure
  • Low anterior resection
  • Primary anastomosis

Cite this

@article{c5b813fa795d4ac4a5e0b20948dc1e78,
title = "Comparison of the efficacy of low anterior resection with primary anastomosis and Hartmann's procedure in advanced primary or recurrent epithelial ovarian cancer",
abstract = "Objective: We compared the efficacy between low anterior resection with primary anastomosis (LARA) and Hartmann's procedure (HP) in advanced primary or recurrent epithelial ovarian cancer (EOC). Study design: We reviewed medical records of 61 patients with advanced primary or recurrent EOC who underwent LARA or HP between January 1998 and August 2008. In 37 patients with primary FIGO stage III-IV EOC, 22 and 15 received LARA and HP, whereas 10 and 14 underwent LARA and HP in 24 patients with recurrent EOC. Results: Postoperative complications (recto-vaginal fistula, leakage at the anastomotic site, postoperative ileus for ≥7 days, wound dehiscence, angina pectoris, acute renal failure, febrile illness, reoperation within 30 days and postoperative death), surgical outcomes (time of operation, estimated blood loss, transfusion, postoperative hospitalization and time to normal diet) were not different between LARA and HP. Progression-free survival (median, 20 vs. 17 months) and overall survivals (median, 70 vs. 36 months) in advanced primary EOC, and surgery-specific survival (median, 32 vs. 17 months) and overall survivals (median, 52 vs. 61 months) in recurrent EOC were also not different between LARA and HP (p > 0.05). Moreover, the recto-sigmoid obstruction after LARA was developed in 9.1{\%} in advanced primary EOC and 10{\%} in recurrent EOC, and the stoma-free rates were high in LARA (90.9{\%} in advanced primary EOC; 90{\%} in recurrent EOC). Conclusions: LARA may be an optimal procedure for bowel surgery without differences in postoperative complication, surgical outcomes and survival when compared with Hartmann's procedure in advanced primary or recurrent EOC. Furthermore, the high stoma-free rate after LARA can improve postoperative quality of life by avoiding the permanent stoma formation.",
keywords = "Epithelial ovarian cancer, Hartmann's procedure, Low anterior resection, Primary anastomosis",
author = "Kim, {Hee Seung} and Kim, {Eun Na} and Jeong, {Seung Yong} and Chung, {Hyun Hoon} and Kim, {Yong Beom} and Kim, {Jae Weon} and Park, {Kyu Joo} and Park, {Noh Hyun} and Song, {Yong Sang} and Park, {Jae Gahb} and Kang, {Soon Beom}",
year = "2011",
month = "6",
doi = "10.1016/j.ejogrb.2011.01.003",
language = "English",
volume = "156",
pages = "194--198",
journal = "European Journal of Obstetrics Gynecology and Reproductive Biology",
issn = "0301-2115",
publisher = "Elsevier Ireland Ltd",
number = "2",

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TY - JOUR

T1 - Comparison of the efficacy of low anterior resection with primary anastomosis and Hartmann's procedure in advanced primary or recurrent epithelial ovarian cancer

AU - Kim, Hee Seung

AU - Kim, Eun Na

AU - Jeong, Seung Yong

AU - Chung, Hyun Hoon

AU - Kim, Yong Beom

AU - Kim, Jae Weon

AU - Park, Kyu Joo

AU - Park, Noh Hyun

AU - Song, Yong Sang

AU - Park, Jae Gahb

AU - Kang, Soon Beom

PY - 2011/6

Y1 - 2011/6

N2 - Objective: We compared the efficacy between low anterior resection with primary anastomosis (LARA) and Hartmann's procedure (HP) in advanced primary or recurrent epithelial ovarian cancer (EOC). Study design: We reviewed medical records of 61 patients with advanced primary or recurrent EOC who underwent LARA or HP between January 1998 and August 2008. In 37 patients with primary FIGO stage III-IV EOC, 22 and 15 received LARA and HP, whereas 10 and 14 underwent LARA and HP in 24 patients with recurrent EOC. Results: Postoperative complications (recto-vaginal fistula, leakage at the anastomotic site, postoperative ileus for ≥7 days, wound dehiscence, angina pectoris, acute renal failure, febrile illness, reoperation within 30 days and postoperative death), surgical outcomes (time of operation, estimated blood loss, transfusion, postoperative hospitalization and time to normal diet) were not different between LARA and HP. Progression-free survival (median, 20 vs. 17 months) and overall survivals (median, 70 vs. 36 months) in advanced primary EOC, and surgery-specific survival (median, 32 vs. 17 months) and overall survivals (median, 52 vs. 61 months) in recurrent EOC were also not different between LARA and HP (p > 0.05). Moreover, the recto-sigmoid obstruction after LARA was developed in 9.1% in advanced primary EOC and 10% in recurrent EOC, and the stoma-free rates were high in LARA (90.9% in advanced primary EOC; 90% in recurrent EOC). Conclusions: LARA may be an optimal procedure for bowel surgery without differences in postoperative complication, surgical outcomes and survival when compared with Hartmann's procedure in advanced primary or recurrent EOC. Furthermore, the high stoma-free rate after LARA can improve postoperative quality of life by avoiding the permanent stoma formation.

AB - Objective: We compared the efficacy between low anterior resection with primary anastomosis (LARA) and Hartmann's procedure (HP) in advanced primary or recurrent epithelial ovarian cancer (EOC). Study design: We reviewed medical records of 61 patients with advanced primary or recurrent EOC who underwent LARA or HP between January 1998 and August 2008. In 37 patients with primary FIGO stage III-IV EOC, 22 and 15 received LARA and HP, whereas 10 and 14 underwent LARA and HP in 24 patients with recurrent EOC. Results: Postoperative complications (recto-vaginal fistula, leakage at the anastomotic site, postoperative ileus for ≥7 days, wound dehiscence, angina pectoris, acute renal failure, febrile illness, reoperation within 30 days and postoperative death), surgical outcomes (time of operation, estimated blood loss, transfusion, postoperative hospitalization and time to normal diet) were not different between LARA and HP. Progression-free survival (median, 20 vs. 17 months) and overall survivals (median, 70 vs. 36 months) in advanced primary EOC, and surgery-specific survival (median, 32 vs. 17 months) and overall survivals (median, 52 vs. 61 months) in recurrent EOC were also not different between LARA and HP (p > 0.05). Moreover, the recto-sigmoid obstruction after LARA was developed in 9.1% in advanced primary EOC and 10% in recurrent EOC, and the stoma-free rates were high in LARA (90.9% in advanced primary EOC; 90% in recurrent EOC). Conclusions: LARA may be an optimal procedure for bowel surgery without differences in postoperative complication, surgical outcomes and survival when compared with Hartmann's procedure in advanced primary or recurrent EOC. Furthermore, the high stoma-free rate after LARA can improve postoperative quality of life by avoiding the permanent stoma formation.

KW - Epithelial ovarian cancer

KW - Hartmann's procedure

KW - Low anterior resection

KW - Primary anastomosis

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U2 - 10.1016/j.ejogrb.2011.01.003

DO - 10.1016/j.ejogrb.2011.01.003

M3 - Article

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VL - 156

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EP - 198

JO - European Journal of Obstetrics Gynecology and Reproductive Biology

JF - European Journal of Obstetrics Gynecology and Reproductive Biology

SN - 0301-2115

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ER -