Comparison of gynecologic cancer risk factors, incidence and mortality trends between South Korea and Israel, 1999–2013

N. Michaan, Sang Yoon Park, Y. J. Won, M. C. Lim

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

Objective: To discuss possible causes of disparities in incidence and mortality rates of ovarian cancer, uterine cancer and cervical cancer between two diverse populations from east and west Asia Methods: Incidence and mortality data from 1999 to 2013 were extracted from Korean and Israeli cancer registries. Age-standardized rates and annual percent changes were calculated. Trends were analyzed using Joinpoint analysis and discussed with respect to risk factor exposure. Results: Age-standardized rate of ovarian cancer significantly increased in Korea (annual percent change 1.7%) but decreased among Jews (annual percent change −2.15%). Age-standardized rate of uterine cancer increased among both Koreans and Israeli Jews (annual percent changes 5.8 and 1.17%, respectively). Incidence of cervical cancer significantly decreased in Korea (annual percent change −3.8%) while remained stable on Israel. Mortality trends paralleled incidence trends with a significant increase in ovarian cancer and uterine cancer mortality in Korea (annual percent changes 1.2 and 4.6%, respectively) and a drop in cervical cancer mortality from 2002 (annual percent change −5.8%). Among Israeli Jews, uterine cancer mortality increased (annual percent change 1.01%), while ovarian cancer mortality decreased (annual percent change −0.58%). Uterine cancer mortality among Arabs declined (annual percent change −0.5%), while cervical cancer mortality remained unchanged. Conclusions: Gynecologic malignancies show different incidence trends in Korea and Israel. Uterine cancer is rising in both countries and is correlated to changing trends in obesity and dietary habits. Ovarian cancer is rising in Korea but declining among Israeli Jews along with changes in parity, childbearing age, contraceptive use and increasing awareness to BRCA gene carriers and risk reduction salpingo-oophorectomy. Cervical cancer is declining in Korea along with an effective screening program implemented. Mortality trends follow incidence trends in both countries.

Original languageEnglish
Pages (from-to)884-891
Number of pages8
JournalJapanese Journal of Clinical Oncology
Volume48
Issue number10
DOIs
StatePublished - 1 Jan 2018

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Republic of Korea
Israel
Uterine Neoplasms
Korea
Mortality
Incidence
Jews
Uterine Cervical Neoplasms
Ovarian Neoplasms
Neoplasms
Far East
Ovariectomy
Feeding Behavior
Risk Reduction Behavior
Contraceptive Agents
Parity
Registries
Obesity

Keywords

  • Cervical cancer
  • Incidence
  • Israel
  • Korea
  • Ovarian cancer
  • Uterine cancer

Cite this

@article{8bd0c9d2425a4c41b8cfc8141ff84cba,
title = "Comparison of gynecologic cancer risk factors, incidence and mortality trends between South Korea and Israel, 1999–2013",
abstract = "Objective: To discuss possible causes of disparities in incidence and mortality rates of ovarian cancer, uterine cancer and cervical cancer between two diverse populations from east and west Asia Methods: Incidence and mortality data from 1999 to 2013 were extracted from Korean and Israeli cancer registries. Age-standardized rates and annual percent changes were calculated. Trends were analyzed using Joinpoint analysis and discussed with respect to risk factor exposure. Results: Age-standardized rate of ovarian cancer significantly increased in Korea (annual percent change 1.7{\%}) but decreased among Jews (annual percent change −2.15{\%}). Age-standardized rate of uterine cancer increased among both Koreans and Israeli Jews (annual percent changes 5.8 and 1.17{\%}, respectively). Incidence of cervical cancer significantly decreased in Korea (annual percent change −3.8{\%}) while remained stable on Israel. Mortality trends paralleled incidence trends with a significant increase in ovarian cancer and uterine cancer mortality in Korea (annual percent changes 1.2 and 4.6{\%}, respectively) and a drop in cervical cancer mortality from 2002 (annual percent change −5.8{\%}). Among Israeli Jews, uterine cancer mortality increased (annual percent change 1.01{\%}), while ovarian cancer mortality decreased (annual percent change −0.58{\%}). Uterine cancer mortality among Arabs declined (annual percent change −0.5{\%}), while cervical cancer mortality remained unchanged. Conclusions: Gynecologic malignancies show different incidence trends in Korea and Israel. Uterine cancer is rising in both countries and is correlated to changing trends in obesity and dietary habits. Ovarian cancer is rising in Korea but declining among Israeli Jews along with changes in parity, childbearing age, contraceptive use and increasing awareness to BRCA gene carriers and risk reduction salpingo-oophorectomy. Cervical cancer is declining in Korea along with an effective screening program implemented. Mortality trends follow incidence trends in both countries.",
keywords = "Cervical cancer, Incidence, Israel, Korea, Ovarian cancer, Uterine cancer",
author = "N. Michaan and Park, {Sang Yoon} and Won, {Y. J.} and Lim, {M. C.}",
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Comparison of gynecologic cancer risk factors, incidence and mortality trends between South Korea and Israel, 1999–2013. / Michaan, N.; Park, Sang Yoon; Won, Y. J.; Lim, M. C.

In: Japanese Journal of Clinical Oncology, Vol. 48, No. 10, 01.01.2018, p. 884-891.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Comparison of gynecologic cancer risk factors, incidence and mortality trends between South Korea and Israel, 1999–2013

AU - Michaan, N.

AU - Park, Sang Yoon

AU - Won, Y. J.

AU - Lim, M. C.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Objective: To discuss possible causes of disparities in incidence and mortality rates of ovarian cancer, uterine cancer and cervical cancer between two diverse populations from east and west Asia Methods: Incidence and mortality data from 1999 to 2013 were extracted from Korean and Israeli cancer registries. Age-standardized rates and annual percent changes were calculated. Trends were analyzed using Joinpoint analysis and discussed with respect to risk factor exposure. Results: Age-standardized rate of ovarian cancer significantly increased in Korea (annual percent change 1.7%) but decreased among Jews (annual percent change −2.15%). Age-standardized rate of uterine cancer increased among both Koreans and Israeli Jews (annual percent changes 5.8 and 1.17%, respectively). Incidence of cervical cancer significantly decreased in Korea (annual percent change −3.8%) while remained stable on Israel. Mortality trends paralleled incidence trends with a significant increase in ovarian cancer and uterine cancer mortality in Korea (annual percent changes 1.2 and 4.6%, respectively) and a drop in cervical cancer mortality from 2002 (annual percent change −5.8%). Among Israeli Jews, uterine cancer mortality increased (annual percent change 1.01%), while ovarian cancer mortality decreased (annual percent change −0.58%). Uterine cancer mortality among Arabs declined (annual percent change −0.5%), while cervical cancer mortality remained unchanged. Conclusions: Gynecologic malignancies show different incidence trends in Korea and Israel. Uterine cancer is rising in both countries and is correlated to changing trends in obesity and dietary habits. Ovarian cancer is rising in Korea but declining among Israeli Jews along with changes in parity, childbearing age, contraceptive use and increasing awareness to BRCA gene carriers and risk reduction salpingo-oophorectomy. Cervical cancer is declining in Korea along with an effective screening program implemented. Mortality trends follow incidence trends in both countries.

AB - Objective: To discuss possible causes of disparities in incidence and mortality rates of ovarian cancer, uterine cancer and cervical cancer between two diverse populations from east and west Asia Methods: Incidence and mortality data from 1999 to 2013 were extracted from Korean and Israeli cancer registries. Age-standardized rates and annual percent changes were calculated. Trends were analyzed using Joinpoint analysis and discussed with respect to risk factor exposure. Results: Age-standardized rate of ovarian cancer significantly increased in Korea (annual percent change 1.7%) but decreased among Jews (annual percent change −2.15%). Age-standardized rate of uterine cancer increased among both Koreans and Israeli Jews (annual percent changes 5.8 and 1.17%, respectively). Incidence of cervical cancer significantly decreased in Korea (annual percent change −3.8%) while remained stable on Israel. Mortality trends paralleled incidence trends with a significant increase in ovarian cancer and uterine cancer mortality in Korea (annual percent changes 1.2 and 4.6%, respectively) and a drop in cervical cancer mortality from 2002 (annual percent change −5.8%). Among Israeli Jews, uterine cancer mortality increased (annual percent change 1.01%), while ovarian cancer mortality decreased (annual percent change −0.58%). Uterine cancer mortality among Arabs declined (annual percent change −0.5%), while cervical cancer mortality remained unchanged. Conclusions: Gynecologic malignancies show different incidence trends in Korea and Israel. Uterine cancer is rising in both countries and is correlated to changing trends in obesity and dietary habits. Ovarian cancer is rising in Korea but declining among Israeli Jews along with changes in parity, childbearing age, contraceptive use and increasing awareness to BRCA gene carriers and risk reduction salpingo-oophorectomy. Cervical cancer is declining in Korea along with an effective screening program implemented. Mortality trends follow incidence trends in both countries.

KW - Cervical cancer

KW - Incidence

KW - Israel

KW - Korea

KW - Ovarian cancer

KW - Uterine cancer

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U2 - 10.1093/jjco/hyy111

DO - 10.1093/jjco/hyy111

M3 - Review article

VL - 48

SP - 884

EP - 891

JO - Japanese journal of clinical oncology

JF - Japanese journal of clinical oncology

SN - 0368-2811

IS - 10

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