Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer

J. Choi, Sang Gyun Kim, Jong Pil Im, Joosung Kim, H. C. Jung, I. S. Song

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Background and study aims: This study aimed to compare the diagnostic accuracy of endoscopic ultrasonography (EUS) with that of conventional endoscopy for staging depth of invasion (T staging) in early gastric cancer. Patients and methods: A total of 955 patients with suspected early gastric cancer were prospectively registered. EUS staging was carried out prospectively by a single endoscopist using either miniprobe or radial EUS depending on the endoscopic appearance of the tumor. Conventional endoscopy staging was performed retrospectively by consensus between two endoscopists who were blinded to the EUS staging. Conventional endoscopy staging was conducted on the basis of endoscopic features such as surface nodularity and fold convergence. Patients underwent either surgical (n=586) or endoscopic resection (n=369) with curative intent. The staging accuracy of each test was compared with the pathological staging of the resected specimen. Results: The presence of a T1m tumor was histologically confirmed in 644 cases (67.4%) and that of a T1sm tumor in 311 cases (32.6%). The overall accuracy of EUS staging was 67.4% (644/955) and that of conventional endoscopy staging was 73.7% (704/955) (P<0.001). The accuracy of miniprobe EUS was significantly higher than that of radial EUS (79.5% vs. 59.6%, P<0.001), but did not differ significantly from that of conventional endoscopy (79.0%). Conclusions: EUS does not substantially impact on pretreatment T staging of patients with early gastric cancer compared with conventional endoscopy. Therefore, EUS may not be necessary routinely, and conventional endoscopy may be sufficient for determining the optimal therapeutic strategy, especially in relation to endoscopic resection for early gastric cancer.

Original languageEnglish
Pages (from-to)705-713
Number of pages9
JournalEndoscopy
Volume42
Issue number9
DOIs
StatePublished - 10 Sep 2010

Fingerprint

Endosonography
Endoscopy
Stomach Neoplasms
Neoplasms

Cite this

@article{07cf3b7d10db498596dec2ca6e0b3105,
title = "Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer",
abstract = "Background and study aims: This study aimed to compare the diagnostic accuracy of endoscopic ultrasonography (EUS) with that of conventional endoscopy for staging depth of invasion (T staging) in early gastric cancer. Patients and methods: A total of 955 patients with suspected early gastric cancer were prospectively registered. EUS staging was carried out prospectively by a single endoscopist using either miniprobe or radial EUS depending on the endoscopic appearance of the tumor. Conventional endoscopy staging was performed retrospectively by consensus between two endoscopists who were blinded to the EUS staging. Conventional endoscopy staging was conducted on the basis of endoscopic features such as surface nodularity and fold convergence. Patients underwent either surgical (n=586) or endoscopic resection (n=369) with curative intent. The staging accuracy of each test was compared with the pathological staging of the resected specimen. Results: The presence of a T1m tumor was histologically confirmed in 644 cases (67.4{\%}) and that of a T1sm tumor in 311 cases (32.6{\%}). The overall accuracy of EUS staging was 67.4{\%} (644/955) and that of conventional endoscopy staging was 73.7{\%} (704/955) (P<0.001). The accuracy of miniprobe EUS was significantly higher than that of radial EUS (79.5{\%} vs. 59.6{\%}, P<0.001), but did not differ significantly from that of conventional endoscopy (79.0{\%}). Conclusions: EUS does not substantially impact on pretreatment T staging of patients with early gastric cancer compared with conventional endoscopy. Therefore, EUS may not be necessary routinely, and conventional endoscopy may be sufficient for determining the optimal therapeutic strategy, especially in relation to endoscopic resection for early gastric cancer.",
author = "J. Choi and Kim, {Sang Gyun} and Im, {Jong Pil} and Joosung Kim and Jung, {H. C.} and Song, {I. S.}",
year = "2010",
month = "9",
day = "10",
doi = "10.1055/s-0030-1255617",
language = "English",
volume = "42",
pages = "705--713",
journal = "Endoscopy",
issn = "0013-726X",
publisher = "Georg Thieme Verlag",
number = "9",

}

Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer. / Choi, J.; Kim, Sang Gyun; Im, Jong Pil; Kim, Joosung; Jung, H. C.; Song, I. S.

In: Endoscopy, Vol. 42, No. 9, 10.09.2010, p. 705-713.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer

AU - Choi, J.

AU - Kim, Sang Gyun

AU - Im, Jong Pil

AU - Kim, Joosung

AU - Jung, H. C.

AU - Song, I. S.

PY - 2010/9/10

Y1 - 2010/9/10

N2 - Background and study aims: This study aimed to compare the diagnostic accuracy of endoscopic ultrasonography (EUS) with that of conventional endoscopy for staging depth of invasion (T staging) in early gastric cancer. Patients and methods: A total of 955 patients with suspected early gastric cancer were prospectively registered. EUS staging was carried out prospectively by a single endoscopist using either miniprobe or radial EUS depending on the endoscopic appearance of the tumor. Conventional endoscopy staging was performed retrospectively by consensus between two endoscopists who were blinded to the EUS staging. Conventional endoscopy staging was conducted on the basis of endoscopic features such as surface nodularity and fold convergence. Patients underwent either surgical (n=586) or endoscopic resection (n=369) with curative intent. The staging accuracy of each test was compared with the pathological staging of the resected specimen. Results: The presence of a T1m tumor was histologically confirmed in 644 cases (67.4%) and that of a T1sm tumor in 311 cases (32.6%). The overall accuracy of EUS staging was 67.4% (644/955) and that of conventional endoscopy staging was 73.7% (704/955) (P<0.001). The accuracy of miniprobe EUS was significantly higher than that of radial EUS (79.5% vs. 59.6%, P<0.001), but did not differ significantly from that of conventional endoscopy (79.0%). Conclusions: EUS does not substantially impact on pretreatment T staging of patients with early gastric cancer compared with conventional endoscopy. Therefore, EUS may not be necessary routinely, and conventional endoscopy may be sufficient for determining the optimal therapeutic strategy, especially in relation to endoscopic resection for early gastric cancer.

AB - Background and study aims: This study aimed to compare the diagnostic accuracy of endoscopic ultrasonography (EUS) with that of conventional endoscopy for staging depth of invasion (T staging) in early gastric cancer. Patients and methods: A total of 955 patients with suspected early gastric cancer were prospectively registered. EUS staging was carried out prospectively by a single endoscopist using either miniprobe or radial EUS depending on the endoscopic appearance of the tumor. Conventional endoscopy staging was performed retrospectively by consensus between two endoscopists who were blinded to the EUS staging. Conventional endoscopy staging was conducted on the basis of endoscopic features such as surface nodularity and fold convergence. Patients underwent either surgical (n=586) or endoscopic resection (n=369) with curative intent. The staging accuracy of each test was compared with the pathological staging of the resected specimen. Results: The presence of a T1m tumor was histologically confirmed in 644 cases (67.4%) and that of a T1sm tumor in 311 cases (32.6%). The overall accuracy of EUS staging was 67.4% (644/955) and that of conventional endoscopy staging was 73.7% (704/955) (P<0.001). The accuracy of miniprobe EUS was significantly higher than that of radial EUS (79.5% vs. 59.6%, P<0.001), but did not differ significantly from that of conventional endoscopy (79.0%). Conclusions: EUS does not substantially impact on pretreatment T staging of patients with early gastric cancer compared with conventional endoscopy. Therefore, EUS may not be necessary routinely, and conventional endoscopy may be sufficient for determining the optimal therapeutic strategy, especially in relation to endoscopic resection for early gastric cancer.

UR - http://www.scopus.com/inward/record.url?scp=77956326773&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1255617

DO - 10.1055/s-0030-1255617

M3 - Article

C2 - 20652857

AN - SCOPUS:77956326773

VL - 42

SP - 705

EP - 713

JO - Endoscopy

JF - Endoscopy

SN - 0013-726X

IS - 9

ER -