Comparación de la sensibilidad a antibióticos de E coli entre prostatitis aguda bacteriana adquirida en la comunidad y la secundaria a biopsia de próstata

Translated title of the contribution: Comparison of antibiotic susceptibility of Escherichia coli between community-acquired and post-prostate biopsy acute bacterial prostatitis

Min Gu Park, Min Chul Cho, Sung Yong Cho, Jeong Woo Lee

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To compare the antibiotic susceptibility of Escherichia coli (E. coli) between community- acquired acute bacterial prostatitis (CA-ABP) and ABP following transrectal ultrasound-guided prostate biopsy (Bx-ABP). METHODS: A total of 4,383 patients underwent prostate biopsy from January 2005 to June 2014. Among these patients, 34 had Bx-ABP; of which 22 patients had E. coli identified in their urine or blood culture. E. coli was also identified in 91 out of 209 patients with CA-ABP in urine or blood culture. We investigated patient and microbiological characteristics. RESULTS: The Bx-ABP (59.1%) group showed a higher bacteremia prevalence than the CA-ABP group (13.2%) (p<0.001). Significant differences in the antibiotic sensitivity to E. coli between the two groups were observed for fluoroquinolone, cephalothin, and gentamicin. The antibiotic sensitivity of fluoroquinolone in the Bx-ABP group was only 27.3%. Amikacin, imipenem, meropenem, amoxicillin/clavulanic acid, and piperacillin/ tazobactam showed more than 95% antibiotic sensitivity in both groups. Bx-ABP was an independent predictive factor for bacteremia by multivariate analysis. CONCLUSIONS: E. coli in Bx-ABP showed a higher incidence of antibiotic resistance and bacteremia than those in CA-ABP. Carbapenem may be a treatment of choice for patients suspected of having sepsis. Considering the recent emergence of carbapenem-resistant bacteria, piperacillin/tazobactam or amikacin may be considered.

Original languageSpanish
Pages (from-to)1018-1025
Number of pages8
JournalArchivos espanoles de urologia
Volume72
Issue number10
StatePublished - 1 Dec 2020

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Prostatitis
Prostate
Escherichia coli
Anti-Bacterial Agents
Biopsy
Bacteremia
Carbapenems
Amikacin
meropenem
Fluoroquinolones
Urine
Cephalothin
Amoxicillin-Potassium Clavulanate Combination
Imipenem
Microbial Drug Resistance
Gentamicins
Sepsis
Multivariate Analysis
Bacteria
Incidence

Keywords

  • Acute bacterial prostatitis
  • Antibiotic susceptibility
  • Community acquired infection
  • Empirical therapy
  • Escherichia coli
  • Escherichia coli
  • Infección adquirida en la comunidad
  • Post biopsia de próstata
  • Post-prostate biopsy
  • Prostatitis aguda bacteriana
  • Sensibilidad a antibióticos
  • Tratamiento empírico

Cite this

@article{6249b1e750d440b09d7cd4f6c63c61d6,
title = "Comparaci{\'o}n de la sensibilidad a antibi{\'o}ticos de E coli entre prostatitis aguda bacteriana adquirida en la comunidad y la secundaria a biopsia de pr{\'o}stata",
abstract = "OBJECTIVES: To compare the antibiotic susceptibility of Escherichia coli (E. coli) between community- acquired acute bacterial prostatitis (CA-ABP) and ABP following transrectal ultrasound-guided prostate biopsy (Bx-ABP). METHODS: A total of 4,383 patients underwent prostate biopsy from January 2005 to June 2014. Among these patients, 34 had Bx-ABP; of which 22 patients had E. coli identified in their urine or blood culture. E. coli was also identified in 91 out of 209 patients with CA-ABP in urine or blood culture. We investigated patient and microbiological characteristics. RESULTS: The Bx-ABP (59.1{\%}) group showed a higher bacteremia prevalence than the CA-ABP group (13.2{\%}) (p<0.001). Significant differences in the antibiotic sensitivity to E. coli between the two groups were observed for fluoroquinolone, cephalothin, and gentamicin. The antibiotic sensitivity of fluoroquinolone in the Bx-ABP group was only 27.3{\%}. Amikacin, imipenem, meropenem, amoxicillin/clavulanic acid, and piperacillin/ tazobactam showed more than 95{\%} antibiotic sensitivity in both groups. Bx-ABP was an independent predictive factor for bacteremia by multivariate analysis. CONCLUSIONS: E. coli in Bx-ABP showed a higher incidence of antibiotic resistance and bacteremia than those in CA-ABP. Carbapenem may be a treatment of choice for patients suspected of having sepsis. Considering the recent emergence of carbapenem-resistant bacteria, piperacillin/tazobactam or amikacin may be considered.",
keywords = "Acute bacterial prostatitis, Antibiotic susceptibility, Community acquired infection, Empirical therapy, Escherichia coli, Escherichia coli, Infecci{\'o}n adquirida en la comunidad, Post biopsia de pr{\'o}stata, Post-prostate biopsy, Prostatitis aguda bacteriana, Sensibilidad a antibi{\'o}ticos, Tratamiento emp{\'i}rico",
author = "Park, {Min Gu} and Cho, {Min Chul} and Cho, {Sung Yong} and Lee, {Jeong Woo}",
year = "2020",
month = "12",
day = "1",
language = "Spanish",
volume = "72",
pages = "1018--1025",
journal = "Archivos Espanoles de Urologia",
issn = "0004-0614",
publisher = "Iniestares, S.A.",
number = "10",

}

TY - JOUR

T1 - Comparación de la sensibilidad a antibióticos de E coli entre prostatitis aguda bacteriana adquirida en la comunidad y la secundaria a biopsia de próstata

AU - Park, Min Gu

AU - Cho, Min Chul

AU - Cho, Sung Yong

AU - Lee, Jeong Woo

PY - 2020/12/1

Y1 - 2020/12/1

N2 - OBJECTIVES: To compare the antibiotic susceptibility of Escherichia coli (E. coli) between community- acquired acute bacterial prostatitis (CA-ABP) and ABP following transrectal ultrasound-guided prostate biopsy (Bx-ABP). METHODS: A total of 4,383 patients underwent prostate biopsy from January 2005 to June 2014. Among these patients, 34 had Bx-ABP; of which 22 patients had E. coli identified in their urine or blood culture. E. coli was also identified in 91 out of 209 patients with CA-ABP in urine or blood culture. We investigated patient and microbiological characteristics. RESULTS: The Bx-ABP (59.1%) group showed a higher bacteremia prevalence than the CA-ABP group (13.2%) (p<0.001). Significant differences in the antibiotic sensitivity to E. coli between the two groups were observed for fluoroquinolone, cephalothin, and gentamicin. The antibiotic sensitivity of fluoroquinolone in the Bx-ABP group was only 27.3%. Amikacin, imipenem, meropenem, amoxicillin/clavulanic acid, and piperacillin/ tazobactam showed more than 95% antibiotic sensitivity in both groups. Bx-ABP was an independent predictive factor for bacteremia by multivariate analysis. CONCLUSIONS: E. coli in Bx-ABP showed a higher incidence of antibiotic resistance and bacteremia than those in CA-ABP. Carbapenem may be a treatment of choice for patients suspected of having sepsis. Considering the recent emergence of carbapenem-resistant bacteria, piperacillin/tazobactam or amikacin may be considered.

AB - OBJECTIVES: To compare the antibiotic susceptibility of Escherichia coli (E. coli) between community- acquired acute bacterial prostatitis (CA-ABP) and ABP following transrectal ultrasound-guided prostate biopsy (Bx-ABP). METHODS: A total of 4,383 patients underwent prostate biopsy from January 2005 to June 2014. Among these patients, 34 had Bx-ABP; of which 22 patients had E. coli identified in their urine or blood culture. E. coli was also identified in 91 out of 209 patients with CA-ABP in urine or blood culture. We investigated patient and microbiological characteristics. RESULTS: The Bx-ABP (59.1%) group showed a higher bacteremia prevalence than the CA-ABP group (13.2%) (p<0.001). Significant differences in the antibiotic sensitivity to E. coli between the two groups were observed for fluoroquinolone, cephalothin, and gentamicin. The antibiotic sensitivity of fluoroquinolone in the Bx-ABP group was only 27.3%. Amikacin, imipenem, meropenem, amoxicillin/clavulanic acid, and piperacillin/ tazobactam showed more than 95% antibiotic sensitivity in both groups. Bx-ABP was an independent predictive factor for bacteremia by multivariate analysis. CONCLUSIONS: E. coli in Bx-ABP showed a higher incidence of antibiotic resistance and bacteremia than those in CA-ABP. Carbapenem may be a treatment of choice for patients suspected of having sepsis. Considering the recent emergence of carbapenem-resistant bacteria, piperacillin/tazobactam or amikacin may be considered.

KW - Acute bacterial prostatitis

KW - Antibiotic susceptibility

KW - Community acquired infection

KW - Empirical therapy

KW - Escherichia coli

KW - Escherichia coli

KW - Infección adquirida en la comunidad

KW - Post biopsia de próstata

KW - Post-prostate biopsy

KW - Prostatitis aguda bacteriana

KW - Sensibilidad a antibióticos

KW - Tratamiento empírico

UR - http://www.scopus.com/inward/record.url?scp=85076056603&partnerID=8YFLogxK

M3 - Article

C2 - 31797804

AN - SCOPUS:85076056603

VL - 72

SP - 1018

EP - 1025

JO - Archivos Espanoles de Urologia

JF - Archivos Espanoles de Urologia

SN - 0004-0614

IS - 10

ER -