Clinicopathologic characteristics of interval gastric cancer in Korea

Mi Sung Park, Ji Young Yoon, Hyunsoo Chung, Hyuk Lee, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background/Aims: Interval gastric cancer (IGC) is defined as cancer that is diagnosed between the time of screening and postscreening esophagogastroduodenoscopy (EGD). Unfortunately, little is known about the characteristics of IGC in Korea, a country with a high incidence of gastric cancer. The aim of this study was to evaluate the clinicopathologic characteristics of IGCs in Korea. Methods: From January 2006 to July 2011, a total of 81,762 subjects underwent screening EGD at Yonsei University Health Promotion Center, Seoul, Korea. We defined missed cancer as cancer diagnosed within 1 year of screening EGD and latent cancer as cancer diag-nosed more than 1 year after EGD. Results: A total of 16 IGC patients (17 lesions; three missed cancers and 14 latent cancers) were identified, with a mean age of 60.68 years and a mean interval time of 19.64 months. IGCs tended to be undifferentiated (12/17, 70.6%), located in the lower body of the stomach (12/17, 70.6%) and exhibited flat/depressed endoscopic morphology (11/17, 64.7%). The patients with missed cancer were generally younger than the patients with latent cancer (51.3 years vs 62.8 years, p=0.037), and the patients with undifferentiated cancer were significantly younger than those with differentiated cancer (57.0 years vs 68.8 years, p=0.008). Conclusions: IGCs tended to be undifferentiated, located in the lower body of the stomach, and exhibited flat/depressed endoscopic morphology.

Original languageEnglish
Pages (from-to)167-173
Number of pages7
JournalGut and Liver
Volume9
Issue number2
DOIs
StatePublished - 1 Jan 2015

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Korea
Stomach Neoplasms
Digestive System Endoscopy
Neoplasms
Stomach
Health Promotion

Keywords

  • Histopathology
  • Interval gastric cancer
  • Latent gastric cancer
  • Missed gastric cancer

Cite this

Park, M. S., Yoon, J. Y., Chung, H., Lee, H., Park, J. C., Shin, S. K., ... Lee, Y. C. (2015). Clinicopathologic characteristics of interval gastric cancer in Korea. Gut and Liver, 9(2), 167-173. https://doi.org/10.5009/gnl13425
Park, Mi Sung ; Yoon, Ji Young ; Chung, Hyunsoo ; Lee, Hyuk ; Park, Jun Chul ; Shin, Sung Kwan ; Lee, Sang Kil ; Lee, Yong Chan. / Clinicopathologic characteristics of interval gastric cancer in Korea. In: Gut and Liver. 2015 ; Vol. 9, No. 2. pp. 167-173.
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Park, MS, Yoon, JY, Chung, H, Lee, H, Park, JC, Shin, SK, Lee, SK & Lee, YC 2015, 'Clinicopathologic characteristics of interval gastric cancer in Korea', Gut and Liver, vol. 9, no. 2, pp. 167-173. https://doi.org/10.5009/gnl13425

Clinicopathologic characteristics of interval gastric cancer in Korea. / Park, Mi Sung; Yoon, Ji Young; Chung, Hyunsoo; Lee, Hyuk; Park, Jun Chul; Shin, Sung Kwan; Lee, Sang Kil; Lee, Yong Chan.

In: Gut and Liver, Vol. 9, No. 2, 01.01.2015, p. 167-173.

Research output: Contribution to journalArticle

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T1 - Clinicopathologic characteristics of interval gastric cancer in Korea

AU - Park, Mi Sung

AU - Yoon, Ji Young

AU - Chung, Hyunsoo

AU - Lee, Hyuk

AU - Park, Jun Chul

AU - Shin, Sung Kwan

AU - Lee, Sang Kil

AU - Lee, Yong Chan

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Y1 - 2015/1/1

N2 - Background/Aims: Interval gastric cancer (IGC) is defined as cancer that is diagnosed between the time of screening and postscreening esophagogastroduodenoscopy (EGD). Unfortunately, little is known about the characteristics of IGC in Korea, a country with a high incidence of gastric cancer. The aim of this study was to evaluate the clinicopathologic characteristics of IGCs in Korea. Methods: From January 2006 to July 2011, a total of 81,762 subjects underwent screening EGD at Yonsei University Health Promotion Center, Seoul, Korea. We defined missed cancer as cancer diagnosed within 1 year of screening EGD and latent cancer as cancer diag-nosed more than 1 year after EGD. Results: A total of 16 IGC patients (17 lesions; three missed cancers and 14 latent cancers) were identified, with a mean age of 60.68 years and a mean interval time of 19.64 months. IGCs tended to be undifferentiated (12/17, 70.6%), located in the lower body of the stomach (12/17, 70.6%) and exhibited flat/depressed endoscopic morphology (11/17, 64.7%). The patients with missed cancer were generally younger than the patients with latent cancer (51.3 years vs 62.8 years, p=0.037), and the patients with undifferentiated cancer were significantly younger than those with differentiated cancer (57.0 years vs 68.8 years, p=0.008). Conclusions: IGCs tended to be undifferentiated, located in the lower body of the stomach, and exhibited flat/depressed endoscopic morphology.

AB - Background/Aims: Interval gastric cancer (IGC) is defined as cancer that is diagnosed between the time of screening and postscreening esophagogastroduodenoscopy (EGD). Unfortunately, little is known about the characteristics of IGC in Korea, a country with a high incidence of gastric cancer. The aim of this study was to evaluate the clinicopathologic characteristics of IGCs in Korea. Methods: From January 2006 to July 2011, a total of 81,762 subjects underwent screening EGD at Yonsei University Health Promotion Center, Seoul, Korea. We defined missed cancer as cancer diagnosed within 1 year of screening EGD and latent cancer as cancer diag-nosed more than 1 year after EGD. Results: A total of 16 IGC patients (17 lesions; three missed cancers and 14 latent cancers) were identified, with a mean age of 60.68 years and a mean interval time of 19.64 months. IGCs tended to be undifferentiated (12/17, 70.6%), located in the lower body of the stomach (12/17, 70.6%) and exhibited flat/depressed endoscopic morphology (11/17, 64.7%). The patients with missed cancer were generally younger than the patients with latent cancer (51.3 years vs 62.8 years, p=0.037), and the patients with undifferentiated cancer were significantly younger than those with differentiated cancer (57.0 years vs 68.8 years, p=0.008). Conclusions: IGCs tended to be undifferentiated, located in the lower body of the stomach, and exhibited flat/depressed endoscopic morphology.

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KW - Interval gastric cancer

KW - Latent gastric cancer

KW - Missed gastric cancer

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