Clinical Use of Tamiflu (Oseltamivir)

Mee Soo Chang, Hee Woo Jun

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Oseltamivir (Tamiflu, the trade name) is a neuraminidase inhibitor used for the treatment and prevention of influenza virus infection as well as those of avian influenza infection. The mechanism of action is inhibition of neuraminidase for blocking the release of newly formed virus particles from the infected respiratory epithelial cells and preventing the further spread of the virus. Development of resistance is rare. The adult dose is 75 mg (p.o.) b.i.d. for 5 days for treatment of influenza. The adverse drug reactions of oseltamivir are very rare but in children and adolescents careful monitoring is needed.

Original languageEnglish
Pages (from-to)757-763
Number of pages7
JournalJournal of the Korean Medical Association
Volume51
Issue number8
DOIs
StatePublished - 1 Aug 2008

Fingerprint

Oseltamivir
Neuraminidase
Influenza in Birds
Virus Diseases
Orthomyxoviridae
Drug-Related Side Effects and Adverse Reactions
Virion
Human Influenza
Names
Epithelial Cells
Viruses
Therapeutics
Infection

Keywords

  • Avian influenza
  • Influenza
  • Oseltamivir

Cite this

Chang, Mee Soo ; Jun, Hee Woo. / Clinical Use of Tamiflu (Oseltamivir). In: Journal of the Korean Medical Association. 2008 ; Vol. 51, No. 8. pp. 757-763.
@article{d465b174cc5b4453b326674d298f9d78,
title = "Clinical Use of Tamiflu (Oseltamivir)",
abstract = "Oseltamivir (Tamiflu, the trade name) is a neuraminidase inhibitor used for the treatment and prevention of influenza virus infection as well as those of avian influenza infection. The mechanism of action is inhibition of neuraminidase for blocking the release of newly formed virus particles from the infected respiratory epithelial cells and preventing the further spread of the virus. Development of resistance is rare. The adult dose is 75 mg (p.o.) b.i.d. for 5 days for treatment of influenza. The adverse drug reactions of oseltamivir are very rare but in children and adolescents careful monitoring is needed.",
keywords = "Avian influenza, Influenza, Oseltamivir",
author = "Chang, {Mee Soo} and Jun, {Hee Woo}",
year = "2008",
month = "8",
day = "1",
doi = "10.5124/jkma.2008.51.8.757",
language = "English",
volume = "51",
pages = "757--763",
journal = "Journal of the Korean Medical Association",
issn = "1975-8456",
publisher = "Korean Medical Association",
number = "8",

}

Clinical Use of Tamiflu (Oseltamivir). / Chang, Mee Soo; Jun, Hee Woo.

In: Journal of the Korean Medical Association, Vol. 51, No. 8, 01.08.2008, p. 757-763.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Clinical Use of Tamiflu (Oseltamivir)

AU - Chang, Mee Soo

AU - Jun, Hee Woo

PY - 2008/8/1

Y1 - 2008/8/1

N2 - Oseltamivir (Tamiflu, the trade name) is a neuraminidase inhibitor used for the treatment and prevention of influenza virus infection as well as those of avian influenza infection. The mechanism of action is inhibition of neuraminidase for blocking the release of newly formed virus particles from the infected respiratory epithelial cells and preventing the further spread of the virus. Development of resistance is rare. The adult dose is 75 mg (p.o.) b.i.d. for 5 days for treatment of influenza. The adverse drug reactions of oseltamivir are very rare but in children and adolescents careful monitoring is needed.

AB - Oseltamivir (Tamiflu, the trade name) is a neuraminidase inhibitor used for the treatment and prevention of influenza virus infection as well as those of avian influenza infection. The mechanism of action is inhibition of neuraminidase for blocking the release of newly formed virus particles from the infected respiratory epithelial cells and preventing the further spread of the virus. Development of resistance is rare. The adult dose is 75 mg (p.o.) b.i.d. for 5 days for treatment of influenza. The adverse drug reactions of oseltamivir are very rare but in children and adolescents careful monitoring is needed.

KW - Avian influenza

KW - Influenza

KW - Oseltamivir

UR - http://www.scopus.com/inward/record.url?scp=79953202881&partnerID=8YFLogxK

U2 - 10.5124/jkma.2008.51.8.757

DO - 10.5124/jkma.2008.51.8.757

M3 - Article

AN - SCOPUS:79953202881

VL - 51

SP - 757

EP - 763

JO - Journal of the Korean Medical Association

JF - Journal of the Korean Medical Association

SN - 1975-8456

IS - 8

ER -