Clinical outcomes of surgical treatment for primary chest wall soft tissue sarcoma

Seung Hwan Yoon, Joon Chul Jung, In Kyu Park, Samina Park, Chang Hyun Kang, Young Tae Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: This study investigated the clinical outcomes of surgical treatment of primary chest wall soft tissue sarcoma (CW-STS). Methods: Thirty-one patients who underwent surgery for CW-STS between 2000 and 2015 were retrospectively reviewed. The disease-free and overall survival rates were estimated using the Kaplan-Meier method, and prognostic factors were analyzed using a Cox proportional hazards model. Results: The median follow-up duration was 65.6 months. The most common histologic type of tumor was malignant fibrous histiocytoma (29%). The resection extended to the soft tissue in 14 patients, while it reached full thickness in 17 patients. Complete resection was achieved in 27 patients (87.1%). There were 5 cases of local recurrence, 3 cases of distant metastasis, and 5 cases of combined recurrence. The 5-year disease-free rate was 49%. Univariate analysis indicated that incomplete resection (p < 0.001) and stage (p=0.062) were possible risk factors for recurrence. Multivariate analysis determined that incomplete resection (p=0.013) and stage (p=0.05) were significantly associated with recurrence. The overall 5- and 10-year survival rates were 86.8% and 64.3%, respectively. No prognostic factor for survival was identified. Conclusion: Long-term primary CW-STS surgery outcomes were found to be favorable. Incomplete microscopic resection and stage were risk factors for recurrence.

Original languageEnglish
Pages (from-to)148-154
Number of pages7
JournalKorean Journal of Thoracic and Cardiovascular Surgery
Volume52
Issue number3
DOIs
StatePublished - 1 Jan 2019

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Thoracic Wall
Sarcoma
Recurrence
Survival Rate
Malignant Fibrous Histiocytoma
Proportional Hazards Models
Disease-Free Survival
Multivariate Analysis
Neoplasm Metastasis
Survival
Neoplasms

Keywords

  • Chest wall
  • Recurrence
  • Sarcoma

Cite this

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title = "Clinical outcomes of surgical treatment for primary chest wall soft tissue sarcoma",
abstract = "Background: This study investigated the clinical outcomes of surgical treatment of primary chest wall soft tissue sarcoma (CW-STS). Methods: Thirty-one patients who underwent surgery for CW-STS between 2000 and 2015 were retrospectively reviewed. The disease-free and overall survival rates were estimated using the Kaplan-Meier method, and prognostic factors were analyzed using a Cox proportional hazards model. Results: The median follow-up duration was 65.6 months. The most common histologic type of tumor was malignant fibrous histiocytoma (29{\%}). The resection extended to the soft tissue in 14 patients, while it reached full thickness in 17 patients. Complete resection was achieved in 27 patients (87.1{\%}). There were 5 cases of local recurrence, 3 cases of distant metastasis, and 5 cases of combined recurrence. The 5-year disease-free rate was 49{\%}. Univariate analysis indicated that incomplete resection (p < 0.001) and stage (p=0.062) were possible risk factors for recurrence. Multivariate analysis determined that incomplete resection (p=0.013) and stage (p=0.05) were significantly associated with recurrence. The overall 5- and 10-year survival rates were 86.8{\%} and 64.3{\%}, respectively. No prognostic factor for survival was identified. Conclusion: Long-term primary CW-STS surgery outcomes were found to be favorable. Incomplete microscopic resection and stage were risk factors for recurrence.",
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Clinical outcomes of surgical treatment for primary chest wall soft tissue sarcoma. / Yoon, Seung Hwan; Jung, Joon Chul; Park, In Kyu; Park, Samina; Kang, Chang Hyun; Kim, Young Tae.

In: Korean Journal of Thoracic and Cardiovascular Surgery, Vol. 52, No. 3, 01.01.2019, p. 148-154.

Research output: Contribution to journalArticle

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T1 - Clinical outcomes of surgical treatment for primary chest wall soft tissue sarcoma

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AU - Jung, Joon Chul

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AU - Kang, Chang Hyun

AU - Kim, Young Tae

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